Choice-specific sequences in parietal cortex during a virtual-navigation decision task — TEI-tagged view

Harvey, Coen, Tank · 2012 · neuroscience · doi:10.1038/nature10918 · full text at the source · TEI xml · tagged edition · index · concepts · authors
Where this record's text came from. faceted 2026-08 by reading the locally held text (xml); every evidence string verified as an exact substring of that text before merging. Method is a problem for the controlled vocabulary: the primary technique is two-photon calcium imaging of GCaMP3 in behaving mice, which is not one of the listed method values. 'electrophysiology' was recorded as the nearest listed term, and the quoted evidence is deliberately the paper's own extracellular electrophysiological confirmation rather than the imaging sentence, so the tag and its quote agree. The verbatim imaging sentence, if a finer vocabulary is later adopted, is: "We used two-photon microscopy to image layer 2/3 PPC neurons expressing the genetically-encoded calcium indicator GCaMP3, which increases in fluorescence intensity in response to action potential firing 35 (Methods)." Prior work is cited only by number, so relation targets are described. 2026-08-12 and 2026-08-15 schema-0.3 passes: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
14 quotations on this page contain a reference number where the paper printed a superscript. This journal style prints citations as raised numerals — parameters12,13 — and the extraction flattened them into the line, so the sentence reads parameters 12 , 13 . The digits are citation markers and not part of what the author wrote. The quotes keep them for the same reason they keep every other extraction fault: a quote is reproduced exactly or it proves nothing.
Other fields define these differently the same word, defined another way in another discipline
principal component analysis 5 fields · working memory 4 fields
Tags on this paper every tag the record carries, whether or not the words occur in the text below — a number is how many papers in the corpus carry that tag; a tag with no number is unique to this paper
posterior parietal cortex7 PPC13 sequence of neuronal activation sustained firing rate changes low-dimensional2 high-dimensional3 recurrent attractor network models neuronal circuit trajectory choice-specific cells task-modulated cells muscimol3 GCaMP32 virtual T-maze place cells13 functional columns center-of-mass2 principal component analysis37 electrophysiology110

Our tag layer for this paper

Cross-disciplinary analysis
content-tags & facets: phenomenon · claim-type · cross-domain-transfer · mechanism · claim-relation · replication-status · limitation — grounded in the full text
phenomenonchoice-specific neuronal sequences in posterior parietal cortex— “When the activity patterns of all the choice-specific, task-modulated cells were ordered according to the time profile of their Ca 2+ transients, the active periods across cells were staggered relative to one another in time forming a sequence of neuronal activation covering the entire trial length ( Fig. 2c–d , Supplementary Fig. 7c ).”
claim-typeexistence— “Distinct sequences of neurons were triggered on trials with opposite behavioral choices and defined divergent, choice-specific trajectories through a state space of neuronal population activity.”
method — evidence— “Similar choice-specific, task-modulated activity patterns were observed in extracellular electrophysiological recordings ( Supplementary Figs. 10–11 ).”
object of study — evidence— “The posterior parietal cortex (PPC) plays an important role in many cognitive behaviors; however, the neural circuit dynamics underlying PPC function are not well understood.”
research question — evidence— “We explored whether PPC dynamics are best described in terms of cell classes or high-dimensional dynamics. During a navigation-based decision task the dynamics were high-dimensional: neurons were active in choice-specific sequences in which information moves from one neuronal population to another across time in the task; although the…
contribution — evidence— “During working memory decision tasks the PPC may therefore perform computations through sequence-based circuit dynamics, rather than long-lived stable states, implemented using anatomically intermingled microcircuits.”
transferfrom dynamical systems and invertebrate neuroscience: the state-space trajectory view of population activity, taken explicitly from work on behavioural choice in the leech nervous system— “Our results motivate consideration of a conceptual framework for decision-making and working memory in which sensory information used for the decision activates a neuronal sequence of activity. The sequence begins in a choice-independent state, which could be mediated by neurons that are not choice-specific ( Supplementary Fig. 7b ), and then…transfers[0]
transferfrom computational models of memory: feedforward architectures and liquid state machines, offered as possible implementations— “During working memory decision tasks the PPC may therefore perform computations through sequence-based circuit dynamics, rather than long-lived stable states, implemented using anatomically intermingled microcircuits.”transfers[1]
mechanismA decision is reached when the evolving activity sequence intersects one of the choice-specific trajectories in population state space— “A decision is proposed to be reached when the sequence of activity intersects a choice-specific trajectory; different decisions involve intersections with different trajectories.”mechanisms[0]
mechanismGrowing state-space separation between the two choice trajectories over the trial progressively raises the barrier to reversing a decision— “Changing decisions would occur through transitions between trajectories, but as time progresses in the task, the state space distance between trajectories increases, in effect creating a larger barrier to change.”mechanisms[1]
mechanismThe parietal cortex switches between sustained-activity and sequence-based dynamical regimes according to the spatiotemporal demands of the behavioral task— “A possible explanation for heterogeneity and sequences in our experiments versus stereotypy and low-dimensional dynamics, which have been emphasized in previous recordings and models of PPC activity 1 , 13 – 18 , 20 – 21 , is that the PPC adopts different dynamics depending on the demands of the behavioral task.”mechanisms[2]
mechanisminformation moves from one neuronal population to another across the trial, each cell active for only a fraction of it— “We explored whether PPC dynamics are best described in terms of cell classes or high-dimensional dynamics. During a navigation-based decision task the dynamics were high-dimensional: neurons were active in choice-specific sequences in which information moves from one neuronal population to another across time in the task; although the…mechanisms[3]
mechanisma proposed framework: the sequence starts choice-independent, then moves toward one choice-specific trajectory, and the growing state-space distance between trajectories acts as a barrier to changing the decision— “Our results motivate consideration of a conceptual framework for decision-making and working memory in which sensory information used for the decision activates a neuronal sequence of activity. The sequence begins in a choice-independent state, which could be mediated by neurons that are not choice-specific ( Supplementary Fig. 7b ), and then…mechanisms[4]
mechanismchoice can be decoded from about 65 neurons within 250 microns, above chance in cue, delay and turn periods— “It was possible, from the activity of a small population of neurons located in close anatomical proximity (~65 neurons separated by < 250 µm), to predict the mouse’s choice on single correct…mechanisms[5]
mechanismfunctionally distinct subnetworks are anatomically interlaced, implying highly specific synaptic connectivity rather than spatial clusteringmechanisms[6]
mechanismthe mouse PPC is located first by retrograde and anterograde labelling, since the region had not been characterised in this species
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mechanisms[7]
mechanismnecessity established by muscimol inactivation, with a visually-guided version of the task as the control for visual and motor deficits
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mechanisms[8]
mechanismtrials aligned to cue offset, turn onset and trial end, because running speed and turn position varied across trials and mice
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mechanisms[9]
extends previous work on spatial intermixing of response properties in sensory cortex, motor cortex and hippocampus (refs 12, 31–32)
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claim_relations[0]
contradicts models predicting spatial clustering of similar response patterns and connectivity from axonal-dendritic overlap (refs 46–47)
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claim_relations[1]
builds-on studies identifying cortical sequences of activity states during working memory tasks (refs 27–30)
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claim_relations[2]
extends the trajectory account of behavioural choice first developed for the leech nervous system (ref. 37)
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claim_relations[3]
contradicts the account of PPC as classes of cells with sustained activity spanning whole task periods
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claim_relations[4]
contradicts models predicting spatial clustering of similar response patterns, as in functional columns
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claim_relations[5]
extends reports of cortical activity sequences during working memory in prefrontal cortex and hippocampus
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claim_relations[6]
distinguishes-from hippocampal place cells, since PPC cells did not encode location on a linear track
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claim_relations[7]
qualifies drift-diffusion and recurrent winner-take-all models of decision-making
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claim_relations[8]
reconciles the primate literature reporting persistent activity, by proposing the task demands select the dynamics
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claim_relations[9]
sensesequence here means each neuron active for only a fraction of a task period with different cells active at different times - explicitly opposed to a class of cells sharing one time course
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senses[0]
sensehigh-dimensional vs low-dimensional is used as the criterion separating the two accounts: low-dimensional means each cell's activity is an amplitude-scaled copy of one prototypical time series
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senses[1]
sensedelay cell, cue cell and response cell are treated as possibly artifactual categories - the paper finds the three groups but shows sequences inside each one
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senses[2]
sensemouse PPC is a stipulated object: the region was located by its afferents, efferents and position relative to visual and somatosensory cortex, then declared to be PPC
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senses[3]
senseneuronal circuit trajectory - the population state as a point in an n-dimensional space with one dimension per neuron
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senses[4]
controltwo versions of the virtual T-maze differing ONLY in the cue period and the reward location — held — rules out everything the two mazes share - the visual environment, the running, the task structure - leaving the cue and the reward as the only thing a difference in neural activity can be about
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controls[0]
differs inmodels predicting spatial clustering of similar response patterns and connectivity from axonal-dendritic overlap (refs 46–47) — spatial clustering and connectivity rule: the opposing models EMPHASIZED THE SPATIAL CLUSTERING OF SIMILAR RESPONSE PATTERNS, AS IN FUNCTIONAL COLUMNS, AND PROPOSE CONNECTIVITY DEFINED BY AXONAL-DENDRITIC OVERLAP WITHOUT FINE-SCALE SPECIFICITY
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claim_relations[1]
differs inthe account of PPC as classes of cells with sustained activity spanning whole task periods — homogeneous classes against sequences: CLASSES OF CELLS WITH HOMOGENEOUS ACTIVITY PATTERNS WERE NOT PRESENT. RATHER, CHOICE-SPECIFIC SEQUENCES OF NEURONS WERE ACTIVATED IN ALL BEHAVIORAL PERIODS
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claim_relations[4]
differs inmodels predicting spatial clustering of similar response patterns, as in functional columns — the same parameter as item 1 - spatial clustering, AS IN FUNCTIONAL COLUMNS, against fine-scale specificity
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claim_relations[5]
differs inhippocampal place cells, since PPC cells did not encode location on a linear track — THE AXIS IS A SPECIFIC TASK THAT SEPARATES THEM. 'It seems unlikely that PPC neurons only provided location information in A CONTEXT-DEPENDENT MANNER, LIKE HIPPOCAMPAL PLACE CELLS, BECAUSE UNLIKE PLACE CELLS PPC NEURONS DID NOT ENCODE SPATIAL LOCATION DURING A LINEAR TRACK TASK.' The distinction is drawn by a task the alternative account predicts they would pass - so the axis names the experiment that discriminates, not a property of either population.
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claim_relations[7]
differs indrift-diffusion and recurrent winner-take-all models of decision-making — what the dynamics settle into: DECISIONS ARE REACHED WHEN THE ACTIVITY APPROACHES A CHOICE-SPECIFIC FIXED POINT WITH WORKING MEMORY MAINTAINED AS STABLE ACTIVITY AT THAT POINT, and THE TRAJECTORIES ARE DEFINED BY RELATIVELY HOMOGENEOUS changes - against a sequence
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claim_relations[8]
differs inthe primate literature reporting persistent activity, by proposing the task demands select the dynamics — the task the animal was doing: THE PPC ADOPTS DIFFERENT DYNAMICS DEPENDING ON THE DEMANDS OF THE BEHAVIORAL TASK, which is offered as the explanation for HETEROGENEITY AND SEQUENCES IN OUR EXPERIMENTS VERSUS STEREOTYPY AND LOW-DIMENSIONAL DYNAMICS
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claim_relations[9]
auditlow-dimensional —operationalised-as→ recurrent attractor network models — Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but low-dimensional dynamics 'CAN BE REPRODUCED in' recurrent attractor models; operationalised-as is loose.
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concept_edges[1]
notelow-dimensional —operationalised-as→ recurrent attractor network models — the model is what makes the dimensionality claim testable - each cell an amplitude-scaled copy of one time series
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concept_edges[1]
weightlow-dimensional —operationalised-as→ recurrent attractor network models — 0.9
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concept_edges[1]
edgechoice-specific cells —part-of→ task-modulated cells
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concept_edges[3]
differs inPPC —distinct-from→ place cells — THE AXIS IS A NEGATIVE TEST USED TO RULE OUT AN ALTERNATIVE. 'It seems unlikely that PPC neurons only provided location information in A CONTEXT-DEPENDENT MANNER, LIKE HIPPOCAMPAL PLACE CELLS, BECAUSE UNLIKE PLACE CELLS PPC NEURONS DID NOT ENCODE SPATIAL LOCATION DURING A LINEAR TRACK TASK.' The comparison is not offered as a finding about PPC - it is offered as the reason a competing interpretation fails, so the axis is what the alternative would have predicted.
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concept_edges[4]
notePPC —distinct-from→ place cells — argued from a negative result on a linear track, not from a positive dissociation
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concept_edges[4]
weightPPC —distinct-from→ place cells — 0.9
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concept_edges[4]
outcome (stated by the tagger, no quotation)control — heldcontrols[0]
for which uselimitation — every decision-related claim in the paper: OUR BEHAVIORAL PARADIGM DID NOT ISOLATE THE DECISION-MAKING PROCESS
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limitations[0]
for which uselimitation — the functional role of the sequences: SEQUENCES MAY THEREFORE PLAY A ROLE IN SOME ASPECT OF DECISION-RELATED PROCESSES, BUT FURTHER EXPERIMENTS WILL BE NECESSARY
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limitations[1]
for which uselimitation — the spatial-organisation result: the weak distance dependence of pairwise correlation may be an optical artefact rather than real spatial structure
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limitations[2]
for which uselimitation — the generality of the sequence result: DIFFERENT REGIONS OR LAYERS OF THE PPC MAY HAVE DIFFERING ACTIVITY DYNAMICS, OR THE DYNAMICS OF RODENT AND PRIMATE PPC CIRCUITS MAY DIFFER
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limitations[3]
for which uselimitation — any role for the sequences in the decision itself: OUR BEHAVIORAL PARADIGM DID NOT ISOLATE THE DECISION-MAKING PROCESS
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limitations[4]
duplicate oflimitation — limitations[2]
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limitations[5]
for which uselimitation — the same scope as limitations[2] - the weak distance-correlation relationship may be overlapping fluorescence rather than real spatial organisation
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limitations[5]
for which uselimitation — the disagreement with the primate literature, which is left unresolved among four alternatives: SEQUENCES ... MAY BE PRESENT IN THE PRIMATE PPC DURING TRADITIONAL TASKS BUT HAVE YET TO BE IDENTIFIED
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limitations[6]
for which uselimitation — what an active cell in the sequence encodes: NAVIGATION, MEMORY, AND CHOICE INFORMATION MAY BE COMBINED IN THE SEQUENCES, and spatial and temporal progression through the task are highly correlated
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limitations[7]
for which uselimitation — every use of the label 'mouse PPC' and every cross-species comparison built on it: BECAUSE THE LOCATION OF THE MOUSE PPC HAS NOT BEEN CHARACTERIZED, WE FIRST PERFORMED RETROGRADE AND ANTEROGRADE LABELING EXPERIMENTS TO LOCATE IT ANATOMICALLY ... CONSISTENT WITH THE RAT AND PRIMATE PPC
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limitations[8]
replicationuntested
limitationThe task confounds the decision with ongoing navigation, so the decision process itself was not isolated.
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limitations[0]
limitationWhether the sequences serve decision-related processes remains to be tested.
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limitations[1]
limitationThe weak distance-dependence of pairwise correlation may be an optical artefact rather than real spatial organisation.
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
limitations[2]
limitationThe result may not generalise across PPC regions, layers or species.
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limitations[3]
limitationthe paradigm does not isolate decision-making, so the role of sequences in the decision itself is untested
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limitations[4]
limitationthe weak distance-correlation relationship may be overlapping fluorescence rather than real spatial organisation, and the paper declines to choose
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limitations[5]
limitationfour rival explanations are offered for why this result differs from the primate literature and none is selected
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limitations[6]
limitationspatial and temporal progression through the task were highly correlated, so what the active cell encodes cannot be separated
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limitations[7]
limitationthe mouse PPC is a stipulated region, defined by projection pattern and position rather than by any functional criterion
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limitations[8]
Content tags
content-observations: finding · quantity · variable · definition · key-term — grounded in the full text
findingIndividual parietal neurons were each active only briefly, and their brief activations were staggered in time so that the population formed a sequence spanning the whole trial.
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content_tags.findings[0]
findingDifferent sequences of neurons ran on left- versus right-choice trials, making the sequences choice-specific.
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content_tags.findings[1]
findingSilencing the posterior parietal cortex with muscimol dropped memory-guided task accuracy to near chance without changing how many trials the mice ran.
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content_tags.findings[2]
findingThe same inactivation did not significantly affect a visually-guided version of the task.
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content_tags.findings[3]
findingCells preferring left versus right choices were anatomically intermingled rather than spatially segregated, since pair selectivity difference did not vary with inter-cell distance.
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content_tags.findings[4]
findingA small, anatomically local population of neurons was enough to decode the animal's upcoming choice above chance throughout the cue, delay and turn periods.
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content_tags.findings[5]
findingDifferences in the animals' running trajectories between left and right trials could not account for the choice-specific activity.
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content_tags.findings[6]
findingThe sequential ordering was not an artifact of sorting, because shuffled data produced no comparable sequences.
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content_tags.findings[7]
findingactivity forms a sequence spanning the entire trial, with cells staggered in time
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content_tags.findings[8]
findingdifferent sequences run on left and right choice trials
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content_tags.findings[9]
findingthe sequences survive shuffling controls, so they are not an artifact of sorting cells by peak time
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content_tags.findings[10]
findingcells fall into cue, delay and turn groups, but each group contains a sequence rather than a class
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content_tags.findings[11]
findingno classes of cells with homogeneous activity patterns were present
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content_tags.findings[12]
findingleft- and right-choice-preferring cells were anatomically intermixed
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content_tags.findings[13]
findingmuscimol in PPC drops memory-guided performance to chance without affecting trial rate
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content_tags.findings[14]
findingthe same inactivation leaves the visually-guided version of the task intact
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content_tags.findings[15]
findingrunning trajectory parameters could not explain the choice-specific activity
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content_tags.findings[16]
findingpassive viewing and a linear track produced far less location-specific activity than the real task
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content_tags.findings[17]
findingindividual trajectories switched between the mean correct left and right choice trajectories, most often during the delay
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.findings[18]
quantity83 ± 9% — mean behavioral accuracy of mice on the memory-guided T-maze task
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[0]
quantity54 ± 5% — fraction of trials correct after bilateral muscimol inactivation of PPC (near the 50% chance level)
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[1]
quantity~71% — proportion of task-modulated cells that were choice-specific
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[2]
quantityn = 404 cells from 6 mice — total number of choice-specific, task-modulated cells pooled across animals
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[3]
quantity< 100 micrometers — the microcircuit length scale over which functionally distinct cells were anatomically intermixed
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[4]
quantity63% of error trials, 20% of correct trials — share of trials on which the population trajectory switched selectivity during the delay or late cue period
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[5]
quantitysimulated runs: 1.3%, linear track: 5.8%, T-maze: 32.3% — fraction of neurons with significant location-specific activity increases in each of the three conditions
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[6]
quantity~65 neurons separated by < 250 µm — size and anatomical spread of the neuronal population sufficient to decode choice above chance
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[7]
quantity83 plus or minus 9% correct, p < 0.0001 vs 50% — behavioural accuracy
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[8]
quantityabout 65 cells per field of view, range 37 to 94 — simultaneous imaging yield
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[9]
quantityabout 73% of highly active cells were task-modulated — proportion carrying task signal
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[10]
quantityabout 71% of task-modulated cells were choice-specific — proportion distinguishing left from right
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[11]
quantity11 plus or minus 8% of trial time points with a transient — how briefly each cell is active
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[12]
quantitysimulated runs 1.3%, linear track 5.8%, T-maze 32.3% — fraction of cells with location-specific activity, the control comparison
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[13]
quantitycue 5.1 plus or minus 2.6 s, delay 4.2 plus or minus 1.2 s, turn 3.0 plus or minus 1.8 s — task period durations
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[14]
quantityEVIDENCE CORRECTED (RE-GROUNDED - THE POINTER WAS WRONG, NOT THE CLAIM) · no injections 87 plus or minus 7%, saline 85 plus or minus 5%, muscimol 54 plus or minus 5% — the inactivation effect
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[15]
retractedquantity — RE-GROUNDED - THE POINTER WAS WRONG, NOT THE CLAIM. The old evidence was verbatim, anchored and correctly cut, and it contained NONE of this claim's numbers (54, 85, 87). The paper states the claim in one sentence elsewhere and the tagger did not use it. the project, 2026-08-23: 'WE HAVE SPENT THE DAY VERIFYING THAT QUOTES ARE REAL AND NONE OF IT ASKS WHETHER THEY ARE RELEVANT.' Confirmed by reading the claim, the old span and the candidate together; the candidate carries every number AND the claim's own content words.content_tags.quantities[15]
variablePPC inactivation (independent)
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.variables[1]
variableneuronal activity (dependent)
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.variables[2]
variableanatomical distance (independent)
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.variables[5]
variabletrial-type selectivity
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.variables[6]
variabletrajectory selectivity index
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.variables[9]
definitionchoice-specific cells
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.definitions[0]
definitionneuronal circuit trajectory
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content_tags.definitions[1]
definitionactivity state of the circuit
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.definitions[2]
definitiont COM
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.definitions[3]
definitiontrajectory selectivity index
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.definitions[4]
definitionneuronal circuit trajectory
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content_tags.definitions[5]
definitionlow-dimensional dynamics
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content_tags.definitions[6]
definitiontask-modulated cells
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.definitions[7]
key-termsposterior parietal cortex, choice-specific, sequence, working memory, state space, neuronal circuit trajectory, low-dimensional, high-dimensional, recurrent attractor network models, task-modulated, muscimol, GCaMP3, virtual T-maze, place cells, functional columns, microcircuit, principal component analysis, delay period, liquid state machines, motifs
Statistics — cross-field join keys
field-invariant statistical terms, used in their statistical sense (gated on a number / symbol / test). A p-value or a standard deviation means the SAME thing in physics, biology, psychology and sociology — so these are the strongest cross-field join keys. Grounded verbatim.
t-test p
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.statistics[0]
principal component analysis as written: principal component analysis (PCA)
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content_tags.statistics[1]
correlation as written: Pearson’s correlations
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content_tags.statistics[2]
rank correlation ρ as written: Spearman’s correlation
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content_tags.statistics[3]
Kolmogorov-Smirnov test p as written: KS test
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content_tags.statistics[4]
multiple regression as written: multiple regression analysis
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content_tags.statistics[5]
factor analysis / dimensionality reduction as written: factor analysis for dimensionality reduction
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content_tags.statistics[6]
classifier (decoding accuracy) as written: a classifier based on the distance from an individual trial trajectory
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content_tags.statistics[7]
shuffle / permutation control as written: shuffled versions of the dataset
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content_tags.statistics[8]
Spearman's correlation of pair difference against distance
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content_tags.statistics[9]
shuffled dataset control
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.statistics[10]
multiple regression on running parameters
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.statistics[11]
principal component analysis
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.statistics[12]
Second readings
a facet read a second time, independently, from its own sentence — and whether the two readings agree
claim typeexistence — a second reading reaching the same value; recorded: existence
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
alternatives.claim_type
methodtwo-photon imaging of GCaMP3 in layer 2/3 PPC of head-restrained mice navigating a virtual T-maze, with muscimol inactivation and open-loop and linear-track controls — a second reading DIFFERING from the recorded value; recorded: electrophysiology
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
alternatives.method
phenomenonsequential population dynamics during working memory and decision — a second reading DIFFERING from the recorded value; recorded: choice-specific neuronal sequences in posterior parietal cortex
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
alternatives.phenomenon

When we have changed our mind. Some entries in the table begin with a word in capitals and the reason for it. EVIDENCE CORRECTED — the finding still stands, but we had quoted the wrong sentence from the paper, and the quotation has been replaced with the right one. RETRACTED — the entry itself was wrong; it stays on the page, marked, with the reason, rather than being deleted. WITHDRAWN AND REPLACED — the entry was wrong, and a corrected version of it appears in the entries below. Each mark carries its own reason, in brackets, because the reasons differ from one entry to the next. An entry we have WITHDRAWN is removed from this page and kept in the record, with its reason. A line reading Audit and a date is a later re-reading of the entry against its whole sentence: DOUBTFUL means it was kept, and the reason says what is loose about it. Quotation marks inside the tagger's sentence. Where a tag is the tagger's own sentence, a phrase in quotation marks inside it is borrowed from the paper — the tagger's wording around it is not. The paper's own sentence is the evidence quote for that row; on this page it is withheld with the article, and the article is at its publisher. Nothing inside quotation marks anywhere on this page is ours: if it is quoted, it is the paper's. Whose words a concept carries. A concept entry records a term the paper itself uses, so the term, the sense given for it, and its evidence are the paper's own words, quoted where the paper fixes them. This is the opposite of a sense entry in the tag table, which is the tagger's sentence about how the paper uses a term. Where a concept entry could not be grounded in the paper's words, the entry says so on its own row.

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