Cristina CosteirapersName, Maria Anjos DixepersName, Ana QueridopersName, Ana RochapersName, Joel VitorinopersName, Cátia SantospersName, Carlos LaranjeirapersName (2024date). “Death Unpreparedness Due to the COVID-19 Pandemic: A Concept Analysis..” Healthcaretitle·j.
Object of study — death unpreparednessterm·dom due to the COVID-19term·key pandemic
Research question — what antecedents, attributes and consequences define death unpreparednessterm·dom in a pandemic
Contribution — a full definition of death unpreparednessterm·dom in a global pandemic scenario
phenomenon · claim-type · cross-domain-transfer · mechanism · claim-relation · replication-status · limitation — grounded in the full text| phenomenon | unpreparedness for COVID-19 deaths carried conceptual, theoretical and practical ambiguities — “The concept needs to be clarified because the unpreparedness for COVID-19 deaths has conceptual, theoretical, and practical ambiguities and complexities” | |
| claim-type | existence — “Concept-defining attributes emerged as clusters of differentiating characteristics, from the perspective of the individual, relational, and contextual spheres” | |
| method — evidence | — “A concept analysis using Walker and Avant’s [ 28 ] strategic method was used to define and elucidate the phenomenon of unpreparedness for death during the COVID-19 pandemic” | |
| object of study — evidence | — “This study aims to analyze the concept map of death unpreparedness due to the COVID-19 pandemic, capturing the relationships among the attributes, antecedents, consequences, and empirical indicators” | |
| research question — evidence | — “In this regard, our main research question is, “What antecedents, attributes, and consequents define the death unpreparedness concept in a global pandemic scenario like COVID-19” | |
| contribution — evidence | — “This study contributed a full definition of death unpreparedness in a global pandemic scenario such as COVID-19” | |
| mechanism | uncertainty and suddenness The pandemic's sudden, uncertain reality kept people from finishing life's tasks and so from readiness for death. — “The uncertainty and suddenness of the new reality implied difficulties in finishing life’s tasks, solving issues with family and friends, and making peace with the inevitable, thus making it difficult to be prepared for death” | mechanisms[0] |
| mechanism | funeral postponement Banned or postponed funerals caused family suffering rooted in religious and cultural beliefs. — “When death occurred, the impossibility of funeral ceremonies or their postponement until 6 months after death [ 60 ] caused family suffering due to religious and cultural beliefs” | mechanisms[1] |
| builds-on | Walker and Avant, concept analysis method — “This method was chosen because it allows an iterative analysis that helps to remediate the lack of consensus over the concept’s key attributes” | claim_relations[0] |
| builds-on | Worden, task model of grieving — “Contrary to an individual perspective of the grieving process, Worden’s approach defends that this process implies the mourner’s active investment and that time by itself is not enough for integrating grief” | claim_relations[1] |
| sense | death unpreparedness (individual) - illness factors, distress at separation and scant grief literacy — “(1) Individual domain: emerging as a phenomenological experience of the dying person and their families, including the attributes, (a) disease-related factors, (b) separation distress, and (c) paucity of death and grief literacy” | senses[0] |
| sense | death unpreparedness (relational) - dying alone, weak communication, existential questions — “(2) Relational domain: referring to (a) dying alone, the intrapersonal experience, (b) poor interpersonal communication and the interpersonal experience, and (c) transcendence facing existential issues experienced by the dying person, family, and healthcare professionals” | senses[1] |
| sense | death unpreparedness (contextual) - disrupted mourning and care, and pandemic stigma — “(3) Contextual domain: encompassing the care, rules, and regulations contributing to death unpreparedness such as (a) disrupted collective mourning and grieving, (b) disrupted compassionate care, and (c) the pandemic’s social stigma” | senses[2] |
| relation | preparedness for caregiving —distinct-from→ preparedness for death — Two operationalizations of preparedness are distinguished in the literature: death preparedness and caregiving preparedness. While “preparedness for caregiving” pertains to a patient’s level of readiness to undertake caregiving responsibilities, “preparedness for death” concerns the readiness of a loved one’s family members to face their demise — “Two operationalizations of preparedness are distinguished in the literature: death preparedness and caregiving preparedness. While “preparedness for caregiving” pertains to a patient’s level of readiness to undertake caregiving responsibilities, “preparedness for death” concerns the readiness of a loved one’s family members to face their demise” | concept_edges[0] |
| weight | preparedness for caregiving —distinct-from→ preparedness for death — 0.75 — “Two operationalizations of preparedness are distinguished in the literature: death preparedness and caregiving preparedness. While “preparedness for caregiving” pertains to a patient’s level of readiness to undertake caregiving responsibilities, “preparedness for death” concerns the readiness of a loved one’s family members to face their demise” | concept_edges[0] |
| effect direction | negative death attitudes —causes→ spiritual well-being — reduces — “Other events that precede death preparedness and can induce an absence of spiritual well-being [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudes from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation” | concept_edges[1] |
| relation | negative death attitudes —causes→ spiritual well-being — Other events that precede death preparedness and can induce an absence of spiritual well-being [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudes from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation — “Other events that precede death preparedness and can induce an absence of spiritual well-being [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudes from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation” | concept_edges[1] |
| weight | negative death attitudes —causes→ spiritual well-being — 0.5 — “Other events that precede death preparedness and can induce an absence of spiritual well-being [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudes from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation” | concept_edges[1] |
| effect direction | communication —causes→ emotional strain — reduces — “Improving communication within a pandemic might potentially alleviate the emotional strain experienced by both impacted families and healthcare professionals” | concept_edges[2] |
| relation | communication —causes→ emotional strain — Improving communication within a pandemic might potentially alleviate the emotional strain experienced by both impacted families and healthcare professionals — “Improving communication within a pandemic might potentially alleviate the emotional strain experienced by both impacted families and healthcare professionals” | concept_edges[2] |
| weight | communication —causes→ emotional strain — 0.45 — “Improving communication within a pandemic might potentially alleviate the emotional strain experienced by both impacted families and healthcare professionals” | concept_edges[2] |
| relation | HCPs —same-as→ Healthcare Professionals — This period was characterized by sudden and rapid changes in the process of dying and grieving, not only for people who were dying but also for their families, informal caregivers, and even Healthcare Professionals (HCPs) — “This period was characterized by sudden and rapid changes in the process of dying and grieving, not only for people who were dying but also for their families, informal caregivers, and even Healthcare Professionals (HCPs)” | concept_edges[3] |
| weight | HCPs —same-as→ Healthcare Professionals — 0.9 — “This period was characterized by sudden and rapid changes in the process of dying and grieving, not only for people who were dying but also for their families, informal caregivers, and even Healthcare Professionals (HCPs)” | concept_edges[3] |
| relation | PGS —same-as→ Pandemic Grief Scale — The Pandemic Grief Scale (PGS), composed of five items, evaluates the presence of problematic grief symptoms in individuals who have experienced the loss of a loved one during the COVID-19 pandemic — “The Pandemic Grief Scale (PGS), composed of five items, evaluates the presence of problematic grief symptoms in individuals who have experienced the loss of a loved one during the COVID-19 pandemic” | concept_edges[4] |
| weight | PGS —same-as→ Pandemic Grief Scale — 0.9 — “The Pandemic Grief Scale (PGS), composed of five items, evaluates the presence of problematic grief symptoms in individuals who have experienced the loss of a loved one during the COVID-19 pandemic” | concept_edges[4] |
| replication | not-applicable | |
| limitation | Articles in Chinese were excluded, which left out experiences from the pandemic's epicenter. — “By excluding articles written in Chinese that refer to experience on the topic, we excluded experiences from the epicenter of COVID-19” | limitations[0] |
| limitation | Article quality was not assessed and interrater reliability was not estimated. — “Furthermore, we did not assess the methodologic quality of the articles (i.e., heterogenous samples; incomplete information, and low evidence level) nor did we estimate interrater reliability using the kappa statistic” | limitations[1] |
| limitation | Walker and Avant's approach gives no strategy for delineating the uses of a concept. — “A limitation of using Walker and Avant’s approach [ 28 ] is the absence of a specific strategy suggested for delineating the applications of the concept” | limitations[2] |
finding · quantity · variable · definition · key-term — grounded in the full text| finding | Unpreparedness for death in COVID-19 is shaped by individual, relational and contextual aspects. — “This concept analysis demonstrates that the unpreparedness for death during COVID-19 is conditioned by individual, relational, and contextual aspects” | content_tags.findings[0] |
| finding | The transition leads either to growth and acceptance or to a misadjusted loss with prolonged grief risk. — “This transition often evolves in two opposite ways: (1) post-traumatic growth and death acceptance, or (2) a misadjusted loss process with a high risk of prolonged grief” | content_tags.findings[1] |
| quantity | 203; 52; 151; 73 — — “The initial search retrieved 203 articles. After removing the 52 duplicates, 151 articles remained to be reviewed by title and abstract. This review excluded 78 articles. A full review of 73 articles was performed” | content_tags.quantities[0] |
| quantity | 44.1%; 41.2%; 8.8%; 5.9% — — “Among the retrieved studies, 44.1% were quantitative research, 41.2% were qualitative research, 8.8% were mixed-methods studies, and 5.9% were narrative reviews” | content_tags.quantities[1] |
| key-terms | death unpreparedness, death preparedness, unexpected death, grief, COVID-19, concept analysis |
| concept | death unpreparedness — a transition in which the processes of information, communication, and relationship between the dying person, family, and HCP are compromised — “The concept of death unpreparedness is defined as a transition in which the processes of information, communication, and relationship between the dying person, family, and HCP are compromised” | concepts[0] |
| concept | unpreparedness — the lack of preparation to face expected responsibilities — “Relatedly, the term “unpreparedness” is defined as the lack of preparation to face expected responsibilities” | concepts[1] |
| concept | unexpected death — death that occurs suddenly and sooner than expected — “However, some catastrophic events can disrupt this possibility and generate an unexpected death, defined as death that occurs suddenly and sooner than expected” | concepts[2] |
| concept | death preparedness — a transition process facilitated by communication with a healthcare provider, which leads to awareness and/or acceptance of end-of-life, as evidenced by the implementation of a plan — “Before COVID-19, death preparedness was conceptualized as a transition process facilitated by communication with a healthcare provider, which leads to awareness and/or acceptance of end-of-life, as evidenced by the implementation of a plan” | concepts[3] |
| concept | emotional preparedness for death — emotionally embracing one’s dying role, being realistic about one’s current circumstances, giving up on unlikely scenarios of survival, and closing, reconciling, and repairing interpersonal links with loved ones to prepare them for life without oneself — “Emotional preparedness for death implies emotionally embracing one’s dying role, being realistic about one’s current circumstances, giving up on unlikely scenarios of survival, and closing, reconciling, and repairing interpersonal links with loved ones to prepare them for life without oneself” | concepts[4] |
| concept | preparedness for caregiving — a patient’s level of readiness to undertake caregiving responsibilities — “Two operationalizations of preparedness are distinguished in the literature: death preparedness and caregiving preparedness. While “preparedness for caregiving” pertains to a patient’s level of readiness to undertake caregiving responsibilities, “preparedness for death” concerns the readiness of a loved one’s family members to face their demise” | concepts[5] |
| concept | preparedness for death — the readiness of a loved one’s family members to face their demise — “Two operationalizations of preparedness are distinguished in the literature: death preparedness and caregiving preparedness. While “preparedness for caregiving” pertains to a patient’s level of readiness to undertake caregiving responsibilities, “preparedness for death” concerns the readiness of a loved one’s family members to face their demise” | concepts[6] |
| concept | uncertainty in illness — the cognitive processes through which individuals interpret events associated with illness and derive meaning from them — “The concept of uncertainty in illness refers to the cognitive processes through which individuals interpret events associated with illness and derive meaning from them” | concepts[7] |
| concept | negative death attitudes — not defined in this paper's own words; attitudes toward death, left by earlier experiences, that precede unpreparedness — “Other events that precede death preparedness and can induce an absence of spiritual well-being [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudes from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation” | concepts[8] |
| concept | spiritual well-being — not defined in this paper's own words; a state whose absence some antecedents of unpreparedness can bring about — “Other events that precede death preparedness and can induce an absence of spiritual well-being [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudes from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation” | concepts[9] |
| concept | communication — not defined in this paper's own words; exchange between families, patients and professionals, strained by pandemic rules — “Improving communication within a pandemic might potentially alleviate the emotional strain experienced by both impacted families and healthcare professionals” | concepts[10] |
| concept | emotional strain — not defined in this paper's own words; the emotional load on bereaved families and professionals — “Improving communication within a pandemic might potentially alleviate the emotional strain experienced by both impacted families and healthcare professionals” | concepts[11] |
| concept | Healthcare Professionals — not defined in this paper's own words; the clinical staff caring for the dying and their families — “This period was characterized by sudden and rapid changes in the process of dying and grieving, not only for people who were dying but also for their families, informal caregivers, and even Healthcare Professionals (HCPs)” | concepts[12] |
| concept | HCPs — Healthcare Professionals — “This period was characterized by sudden and rapid changes in the process of dying and grieving, not only for people who were dying but also for their families, informal caregivers, and even Healthcare Professionals (HCPs)” | concepts[13] |
| concept | Pandemic Grief Scale — not defined in this paper's own words; a five-item self-report scale of problematic grief after a pandemic loss — “The Pandemic Grief Scale (PGS), composed of five items, evaluates the presence of problematic grief symptoms in individuals who have experienced the loss of a loved one during the COVID-19 pandemic” | concepts[14] |
| concept | PGS — Pandemic Grief Scale — “The Pandemic Grief Scale (PGS), composed of five items, evaluates the presence of problematic grief symptoms in individuals who have experienced the loss of a loved one during the COVID-19 pandemic” | concepts[15] |
Full text — tagged
Death Unpreparednessterm·dom Due to the COVID-19term·key Pandemic: A Concept Analysisterm·key.
Abstract The COVID-19term·key pandemic imposed changes upon the capacity of healthcare systems, with significant repercussions on healthcare provision, particularly at end-of-life. This study aims to analyze the concept map of death unpreparednessterm·dom due to the COVID-19term·key pandemic, capturing the relationships among the attributes, antecedents, consequences, and empirical indicators. Walker and Avant’s method was used to guide an analysis of this concept. A literature search was performed systematically, between May 2022 and August 2023, using the following electronic databases on the Elton Bryson Stephens Company (EBSCO) host platform: Medical Literature Analysis and Retrieval System Online (Medline), Psychological Information Database (PsycINFO), Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete, Cochrane Library, and Nursing and Allied Health Collection. Thirty-four articles were retrieved. The unexpected and unpredictable impositions associated with inexperience and unskillfulness in dealing with COVID-19term·key configured challenges for healthcare professionalsterm·dom, family/caregivers, and even the dying person. Nine key attributes emerged in three main domains: (1) Individual: (a) disease-related conditions, (b) separation distress, and (c) scarcity of death and griefterm·key literacy; (2) Relational: (a) Dying alone, (b) poor communicationterm·dom, and (c) existential issues; and (3) Contextual: (a) disrupted collective mourning and grieving, (b) disrupted compassionate care and, (c) pandemic social stigma. This study contributed a full definition of death unpreparednessterm·dom in a global pandemic scenario such as COVID-19term·key. In this sense, feeling unprepared or unready for death brought new challenges to the bioecological resources of those affected. It is essential to embrace strategies capable of providing emotional and spiritual support in the dying process and to respect patient wishes. The lessons learned from COVID-19term·key should be applied to events with a comparable impact to minimize their consequences.
Keywords: preparedness for deathterm·dom, COVID-19term·key, end of life, concept analysisterm·key 1. Introduction The COVID-19term·key disease brought several changes to daily life, even within the death process. The sum of deaths reported by the World Health Organization [WHO] was exceedingly high, reaching 6,956,900 deaths by 9 September 2023 [ 1 , 2 ].
This period was characterized by sudden and rapid changes in the process of dying and grieving, not only for people who were dying but also for their families, informal caregivers, and even Healthcare Professionalsterm·dom (HCPsterm·dom) [ 3 , 4 ]. This global fact changed how populations lived and experienced the death process. Changes in the places of death, the situations of solitary dying created by the sanitary measures, and the impossibility of saying goodbye and performing traditional funeral rites hindered the mourning and griefterm·key process [ 5 , 6 , 7 ]. According to Worden [ 8 ], the grieving process involves four griefterm·key tasks necessary for a critical, irrepressible, and singular adaptation to the new reality: (i) accepting the reality of the loss; (ii) processing the pain of griefterm·key; (iii) adjusting to a world without the dead person; and (iv) finding a way to remember the dead person while embarking on the rest of one’s journey through life. Contrary to an individual perspective of the grieving process, Worden’s approach defends that this process implies the mourner’s active investment and that time by itself is not enough for integrating griefterm·key. More recently, griefterm·key interventions defend an integrative approach based on individual models of griefterm·key, griefterm·key tasks, crisis coping, and family theories of interaction applied to griefterm·key and loss. These should consider several specific aspects of all those involved and identify factors related to the two major sources of distress: traumatic and relational aspects of end-of-life (EoL) caregiving [ 9 , 10 , 11 , 12 , 13 ].
With COVID-19term·key, the possibility of solving the griefterm·key tasks and experiencing death suffered drastic changes. The uncertainty and suddenness of the new reality implied difficulties in finishing life’s tasks, solving issues with family and friends, and making peace with the inevitable, thus making it difficult to be prepared for death [ 14 , 15 ].
Death preparednessterm·dom is a dynamic and complex concept. Incorporating information and attitudes into an integrated awareness and acceptance of one’s impending death is required for cognitive, emotional, and practical preparation for death [ 16 , 17 ]. Emotional preparedness for deathterm·dom implies emotionally embracing one’s dying role, being realistic about one’s current circumstances, giving up on unlikely scenarios of survival, and closing, reconciling, and repairing interpersonal links with loved ones to prepare them for life without oneself [ 18 ]. Numerous research studies have looked at the links between patients’ psychological well-being, quality of life at the EoL, and preparedness for deathterm·dom [ 19 , 20 ]. Evidence also suggests that death preparednessterm·dom fosters a good quality of care [ 21 ].
Two operationalizations of preparedness are distinguished in the literature: death preparednessterm·dom and caregiving preparedness. While “preparedness for caregivingterm·dom” pertains to a patient’s level of readiness to undertake caregiving responsibilities, “preparedness for deathterm·dom” concerns the readiness of a loved one’s family members to face their demise [ 22 ]. Although research has been conducted on both constructs, evaluating, discussing, and promoting death preparednessterm·dom remains a difficult task for policymakers, scholars, and HCPsterm·dom.
High levels of pre-loss griefterm·key promoted poor post-loss adaptation by caregivers of cancer patients [ 23 ]. Conversely, high levels of preparedness were a protective factor against poor adjustment to death. Since these factors influence postmortem adjustment, it is crucial to examine the predictors of death preparednessterm·dom and pre-loss griefterm·key in order to gain insight into the bereavement process and develop specialized interventions to stabilize death preparednessterm·dom and pre-loss griefterm·key [ 22 ]. The pandemic scenario highlighted these concerns. While many studies presume that COVID-19term·key had a detrimental influence on the bereavement process [ 24 ], few studies evaluated the effect of COVID-19term·key on death preparednessterm·dom. Grieving during the pandemic became disorganized because COVID-19term·key deaths were more unexpected and traumatic than other types of deaths [ 25 ].
Research Problem The sudden nature of the COVID-19term·key pandemic altered the processes of death and death preparednessterm·dom, preventing the socialization of death, and determining, in many cases, a high risk of traumatic griefterm·key for surviving family members [ 26 , 27 ].
The concept needs to be clarified because the unpreparednessterm·dom for COVID-19term·key deaths has conceptual, theoretical, and practical ambiguities and complexities. The purpose of this concept analysisterm·key was to develop and clarify the definition of death unpreparednessterm·dom due to COVID-19term·key by describing the connections to related principles and suggesting future implications for practice, research, and education in similar critical events.
In addition to the severity of the situation, the high mortality resulting from the lack of preparedness during the COVID-19term·key pandemic teaches us numerous valuable lessons. With the current state of globalization and interconnectedness, COVID-19term·key was not the first and will not be the last pandemic that humanity must face. During the COVID-19term·key pandemic, significant progress in science and medicine allowed us to detect and manage diseases in ways that earlier pandemics could not have conceived. Stakeholders must exhibit agility and responsiveness to changes. Therefore, an in-depth clarification of death unpreparednessterm·dom experienced during COVID-19term·key, from the perspective of patients, family caregivers, and professionals, will contribute to learning from experience and better preventing the phenomenon. In this regard, our main research question is, “What antecedents, attributes, and consequents define the death unpreparednessterm·dom concept in a global pandemic scenario like COVID-19term·key?”
2. Materials and Methods 2.1. Study Design A concept analysisterm·key using Walker and Avant’s [ 28 ] strategic method was used to define and elucidate the phenomenon of unpreparednessterm·dom for death during the COVID-19term·key pandemic. Those authors opined that concept analysisterm·key is a scientific investigation of a concept to find out its meaning and misconceptions.
Walker and Avant [ 28 ] (p. 8) proposed eight iterative steps involved in concept analysisterm·key: “(1) the selection of a concept; (2) the determination of the analysis purpose; (3) the identification of all possible uses of the concept; (4) the creation of the defining attributes; (5) identification of a model case of the concept; (6) identification of borderline and contrary cases; (7) identification of antecedents and consequences; and, (8) the definition of empirical referents”.
This method was chosen because it allows an iterative analysis that helps to remediate the lack of consensus over the concept’s key attributes [ 28 , 29 ]. Although the model’s stages imply they are sequential, the authors [ 28 ] suggest they are iterative, which means revisiting or returning to former steps as data emerges.
2.2. Study Details In this concept analysisterm·key, we reviewed the relevant published literature. The database research took place between May 2022 and September 2022 and was updated in August 2023. The search for relevant articles was guided by an expert librarian using the following databases through the Elton Bryson Stephens Company (EBSCO) host platform: Medical Literature Analysis and Retrieval System Online (Medline), Psychological Information Database (PsycINFO), Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete, Cochrane Library, and Nursing and Allied Health Collection. The terms were searched individually using the Boolean term OR and then combined using the Boolean term AND. In some instances, truncation, denoted by an asterisk (*), was used to include numerous suffixes within the retrieved search result. Articles were incorporated into the initial screening if the search term was present in both the title and abstract. The search method was derived from the Medline database and applied to additional databases. The following search string was used with a combination of free text and controlled vocabulary: ((“COVID-19term·key” [MeSH term] OR “COVID-19term·key” [Title/Abstract] OR “SARS-CoV-2” [Title/Abstract] OR “Coronavirus Disease-19” [Title/Abstract] OR “COVID-19term·key Pandemics” [Title/Abstract]) AND (“Death” [MeSH term] OR “Death*” [Title/Abstract] OR “Dying Process” [Title/Abstract] OR “Dying Care” [Title/Abstract] OR “Griefterm·key” [MeSH term] “Griefterm·key” [Title/Abstract] OR “Bereavement” [MeSH term] OR “Bereave*” [Title/Abstract] OR “Personal Loss” [Title/Abstract] OR “Preparedness of death” [Title/Abstract] OR “End-of-Life” [Title/Abstract] OR “mourn*” [Title/Abstract] OR “Attitude to Death” [MeSH term] OR “Attitude to Death” [Title/Abstract])).
In the first step, all articles collected were verified to see if they were duplicated and removed in those cases. Furthermore, two independent reviewers (C.C and C.S.) conducted a screening of titles and abstracts to evaluate their suitability based on the inclusion criteria established for the review. The potentially relevant articles were obtained in full text. They were then distributed between four reviewers (A.Q., M.A.D., A.R., and J.V.) who thoroughly evaluated the whole text following the inclusion criteria. In instances where disagreements emerged amongst the reviewers throughout each phase of the selection process, a resolution was sought via the involvement of a third reviewer (C.L.). The references of the identified papers were further examined to locate relevant research.
Articles found during the search were added to reference management software (Mendeley, Elsevier, Amsterdam, The Netherlands, v2.107.0). Data were organized in an Excel spreadsheet that included publication type, study location, design, aims, participants, and key findings. A qualitative thematic analysis [ 30 ], as an iterative process of coding, was used to identify and delineate antecedents, attributes, and consequences. This was an ongoing process of systematically arranging and rearranging data until a complete and relevant set of descriptors was created. This option was useful because the concept under analysis was expected to be unclear in the available literature, given the sudden pandemic reality. Using a synthesis matrix, we summarized the main themes and then categorized them according to the concept analysisterm·key.
Since this is not a systematic review, we did not assess the methodological quality or risk of bias of the included articles, in line with Walker and Avant’s concept analysisterm·key method [ 28 ].
2.3. Eligibility Criteria The inclusion criteria consisted of the following: (1) peer-reviewed articles in English, Portuguese, or Spanish languages; (2) any primary study design (quantitative, qualitative, and mixed-method studies) or secondary study (literature reviews and narrative reviews) containing information about the concept of being unprepared for death due to the COVID-19term·key pandemic; (3) involved one or more representatives of dying people, families, and health professionals; and (4) published in the last three years, between December 2019 and May 2023 (the World Health Organization announced the end of the global pandemic on 5 May 2023).
Exclusion criteria included the gray literature (books, theses, and dissertations), letters to the editor, conference proceedings, and opinion papers.
3. Results The initial search retrieved 203 articles. After removing the 52 duplicates, 151 articles remained to be reviewed by title and abstract. This review excluded 78 articles. A full review of 73 articles was performed. Among these, 41 were excluded because of the type of study (letters to the editor and opinion papers), no focus on the topic, or the data collection before COVID-19term·key, resulting in 32 articles. Two additional articles were retrieved by searching the article bibliographies. In the end, a total of 34 articles were included in the concept analysisterm·key. The results of the search are shown in a flow diagram (see Figure 1 ).
Flow diagram illustrating selection of sources.
Among the retrieved studies, 44.1% were quantitative research, 41.2% were qualitative research, 8.8% were mixed-methods studies, and 5.9% were narrative reviews. Most of the studies (55.9%) were developed in European countries and were focused on bereaved relatives (68.8%). Lastly, 61.8% of the articles were published in 2021, 26.5% were published in 2022, 8.8% were published in 2020, and 2.9% were published in 2023. An overview of included sources is provided in Supplementary Table S1 .
3.1. Definitions and Uses of the Concept The adjective “unprepared” implies being unready or lacking a plan for some activity, purpose, or event. Relatedly, the term “unpreparednessterm·dom” is defined as the lack of preparation to face expected responsibilities [ 31 ].
The encounter with death and the accompanying phase of grieving are significant sources of stress and change in an individual and family’s life trajectory. It can be effectively managed by proactive planning [ 19 ]. However, some catastrophic events can disrupt this possibility and generate an unexpected deathterm·dom, defined as death that occurs suddenly and sooner than expected. An abrupt event resulting in untimely death is accompanied by an element of surprise that implies a lack of knowledge and skill to face the new situation (inexperience and unskillfulness in dealing with death). Unexpected deathsterm·dom are frequently catastrophic events that have significant socioemotional consequences for all. Because the assessment of unexpected events can only be made retrospectively (rather than prospectively), the dying person, families, and HCPsterm·dom are unprepared to face death and the dying process. Lastly, because these events are unpredictable, the etiology is frequently unknown and its course is poorly documented, making this topic more difficult to investigate. Any sort of sudden and/or traumatic death presents significant challenges to the emotional, physical, and spiritual resources of bereaved people.
3.2. Attributes According to the Walker and Avant Model [ 28 ], the process of defining attributes is “the heart” of concept analysisterm·key. The extended literature analysis revealed the most common terms associated with death unpreparednessterm·dom from the perspective of the dying person, family caregivers, and HCPsterm·dom.
Nine key attributes emerged from the literature, experienced in three domains (see Table 1 ): (1) Individual domain: emerging as a phenomenological experience of the dying person and their families, including the attributes, (a) disease-related factors, (b) separation distress, and (c) paucity of death and griefterm·key literacy; (2) Relational domain: referring to (a) dying alone, the intrapersonal experience, (b) poor interpersonal communicationterm·dom and the interpersonal experience, and (c) transcendence facing existential issues experienced by the dying person, family, and healthcare professionalsterm·dom; (3) Contextual domain: encompassing the care, rules, and regulations contributing to death unpreparednessterm·dom such as (a) disrupted collective mourning and grieving, (b) disrupted compassionate care, and (c) the pandemic’s social stigma.
Concept-defining attributes emerged as clusters of differentiating characteristics, from the perspective of the individual, relational, and contextual spheres.
3.3. Antecedents The antecedents comprise the events that precede the concept of interest [ 28 ]. Based on the antecedents, one can identify the different contexts in which a definition may be used. The present research synthesized antecedents related to the concept of preparedness for deathterm·dom during COVID-19term·key into individual and collective domains.
The individual domains that precede the preparedness for deathterm·dom during COVID-19term·key, and interfere with how people construct the concept, are different depending on gender [ 33 ], age [ 58 ], and specific cultural, spiritual, and religious beliefs that can help develop resilience in stressful situations related to health and griefterm·key [ 34 , 40 , 49 , 59 ]. Other events that precede death preparednessterm·dom and can induce an absence of spiritual well-beingterm·dom [ 35 ] include bereavement by a friend’s death [ 43 ], negative death attitudesterm·dom from previous experiences [ 35 , 42 , 46 , 55 , 60 ], and death confrontation.
The concept is preceded by contextual domains: the place of death [ 35 , 47 , 51 , 59 ]; quarantine measures, such as social distancing policies to control contagion and travel prohibitions [ 32 , 34 , 36 , 39 , 40 , 47 , 48 , 50 , 60 , 61 ]; unpredictability, the unexpected increase in death numbers [ 33 , 60 ]; and lockdowns on contacts and visits [ 47 , 48 , 57 , 60 ], which impede the resolution of previous conflicts [ 33 ]. When death occurred, the impossibility of funeral ceremonies or their postponement until 6 months after death [ 60 ] caused family suffering due to religious and cultural beliefs [ 34 ].
Changes in a professional context interfered with non-preparedness for death during COVID-19term·key, such as unpredictability [ 62 ], broader changes [ 54 ] in the workplace and teamwork associated with the rapid opening of new services, changes in prescription patterns, changes in working hours, inconsistent training, changes in human and care resources, and a lack of support for patients and families in the community [ 62 ].
3.4. Consequences Significant strains are placed on the bereaved or healthcare professionalterm·dom’s emotional, physical, and spiritual resources in the event of a sudden death caused by COVID-19term·key. Thus, death unpreparednessterm·dom due to COVID-19term·key has numerous repercussions for the bereaved family and frontline HCPsterm·dom (see Table 2 ).
Consequences of death unpreparednessterm·dom due to COVID-19term·key.
Approaching their EoL, most individuals do not make provisions for the type of health care they would prefer; consequently, they have a diminished chance of experiencing the type of demise they envision. An individual whose demise was anticipated to take several months of gradual deterioration may ultimately pass away unexpectedly. They have been expected to deteriorate progressively, yet, remain healthy until their untimely demise. Those near such fatalities may not perceive them as sudden at all, especially if the deceased was suffering. Notably, preparing to provide care for family members who are gravely ill entails developing an understanding of death, safeguarding against adverse health outcomes, and reducing the burden of bereavement.
3.5. Empirical Referents Without a standardized measurement instrument, death unpreparednessterm·dom is a difficult concept to evaluate, according to the reviewed literature. In the pre-pandemic world, an instrument composed of a single item was used to capture death preparednessterm·dom. Respondents were asked, “If your loved one were to die soon, how prepared would you be for his/her death?”. Response options were “not at all,” “somewhat,” and “very” [ 16 , 17 ]. This instrument’s utility has not been validated during the pandemic period. To mitigate this issue, additional novel tools should be developed, specifically those that adopt a multidimensional perspective encompassing the physical, psychological, familial, social, spiritual, and cultural aspects of death unpreparednessterm·dom in the face of abrupt illnesses and unforeseen circumstances.
In parallel, other instruments capture concepts that may have some proximity to our core concept, namely: (1) The Pandemic Grief Scaleterm·mth (PGSterm·mth), composed of five items, evaluates the presence of problematic griefterm·key symptoms in individuals who have experienced the loss of a loved one during the COVID-19term·key pandemic [ 43 , 57 ]; (2) The Traumatic Griefterm·key Inventory Self Report Plus (TGI-SR+) measures griefterm·key severity [ 66 ]. This 22-item scale evaluates current criteria for Prolonged Griefterm·key Disorder as per DSM-5-TR and ICD-11 [ 36 ]; (3) The ‘Care of the Dying Evaluation’ (CODE™) questionnaire focuses on quality of care and family support during the last days of life [ 55 ]; and (4) The Work and Social Adjustment Scale (WSAS) assesses functional impairment experienced due to a COVID-19term·key loss [ 57 ].
3.6. Case Examples Walker and Avant’s approach [ 28 ] demands the identification of a case model and borderline and contrary cases. Although we used real-life examples, ethical approval was not required since this study did not obtain private identifiable information or patient consent. The construction of each type of case is outlined below.
3.6.1. Case Model A case model is an example that illustrates all the concept’s attributes [ 28 ]. Mr. J. is an 83-year-old man, who lives with his wife of the same age in a village. Both are practicing Catholics. He has two children who emigrated to France. He visits them for a month in the summer. He has a family (nephews and brothers) who live nearby and provide support. Although Mr. J. suffers from several comorbidities associated with a chronic disease, he remains autonomous in his daily activities.
During the 2nd wave of COVID-19term·key, Mr. J. presents an acute myocardial infarction and is accompanied by the emergency medical team to the emergency room of the nearby hospital. His children are informed but do not consider the possibility of death. On admission to the hospital, he tested negative for SARS-CoV-2. Clinical stability is achieved, and he is conscious and oriented. Due to restrictions, face-to-face visits are not allowed, but the family (niece and wife) talk to him by phone. Mr. J. does not understand the family’s absence and expresses concern for his wife who is alone at home.
Due to the lack of differentiated care, he is transferred to a central hospital to perform cardiac catheterization. This takes place without incident, and he returns to the previous hospital. As there are no complications, a discharge plan is formulated. The day before discharge, he began to present a fever and worsened respiratory symptoms, suggestive of COVID-19term·key, which was confirmed. Following a sudden and rampant worsening, he is transferred to the Intensive Care Unit (ICU). His clinical situation continues to decline, and the family is contacted to say goodbye.
The niece contacts the children, who are incredulous and displeased at the lack of timely information about the patient. They seek a virtual visit, which is refused due to a lack of resources. They try to come from France that day but find it very difficult to leave the country. The wife says she is praying for the improvement of her husband’s condition and refuses to visit for fear of catching COVID, as she also has several comorbidities. The niece visits Mr. J. but finds him sedated and ventilated and feels she can no longer communicate with him. The niece is disturbed by the scenario, showing uncontrollable crying and marked anxiety, “But he’s already dead... what do I do now!” [sic]. The visit is carried out with all the protective equipment, but the niece, when prevented from touching her uncle, showed intense feelings of self-blame (sadness, anguish, helplessness, distress, remorse, etc.).
That same night, Mr. J. died without the possibility of receiving a visit from his children, or religious support. The information is transmitted by telephone, during which the professionals express regret for the difficulty in communicationterm·dom and guarantee that Mr. J. and his relatives’ wishes will be satisfied.
Three days after the death, the funeral takes place without the usual farewells and funeral rites or the possibility of significant persons contacting the corpse (impossibility of an open coffin). The wife finds it difficult to accept that Mr. J. has died: “I don’t even know if it’s my husband who is in the coffin, they gave me back the clothes I sent to the funeral home... this is not dignified!” [sic].
The widow is left without close family support. Over time, and due to the traumatic loss, she exhibits disruptive behavior, manifested by daily visits to the cemetery, neglecting self-care, disbelief, and negative thoughts about the future.
The widow often expresses the desire to be comforted by the people of her community, justifying her absence from the community by the village’s installed fear that the whole family could be infected by SARS-CoV-2 (false belief).
This case is a model of being unprepared for death and represents the vast majority of the attributes that characterize the concept [ 28 ].
3.6.2. Borderline Case A borderline case is similar to the concept of interest but does not include all its defining attributes [ 28 ]. Mr. C. is a 41-year-old married salesman with a three-year-old son. He goes on a business trip to Milan in early March 2020 and, one week after his return, he presents a high fever and acute respiratory distress. He waits a week at home, but given his worsening symptoms, he is taken to a central hospital, admitted to the pulmonology service, and subsequently diagnosed with COVID-19term·key. Given the risk of transmission, isolation measures, and visitation restrictions are initiated. Given the sudden and threatening character of the disease, Mr. C. manifests multiple family, financial, and professional concerns.
Already manifesting tiredness, he calls his wife by cell phone and says, “I will be fine, for you and our boy” [sic]. He also refers to concerns about the payment of taxes and access codes to accounts, providing his wife with guidance. After saying goodbye, he cries copiously and expresses to the nurse that he does not want to leave his family with problems to solve. He adds, “I’m not ready to die and I hope I don’t die like this” [sic]. Mr. C.’s health condition worsens, and it is necessary to intubate and sedate him. Given the service’s heavy workload, the family is not informed immediately. A day after being admitted to the Intensive Care Unit (ICU), Mr. C. dies. He was unable to say goodbye to his family as he wished. The family is contacted and informed about Mr. C.’s sudden death and that, due to the State of Emergency, no funeral rites can be performed. The family reacts to this news with dismay. The healthcare professionalterm·dom justifies the lack of previous contact by referring to the virus’ unknown behavior and the constraints associated with the increasing number of infections.
This is the borderline case, highlighting about 50% of the attributes [ 28 ] of non-preparedness: unpredictability and sudden character; separation distress; poor quality of communicationterm·dom between family and professionals; lack of team strategies; and absence of rituals. However, Mr. C. is aware of his condition, tries to make plans, and communicates his wishes and concerns to family and professionals.
3.6.3. Contrary Case According to Walker and Avant, a contrary example is a case that does not exemplify the concept under analysis [ 28 ]. Mrs. M. is an autonomous elderly woman with comorbidities, living in a nursing home, and having family support from her three children. In March 2021, she began to have respiratory distress compatible with a moderate SARS-CoV-2 infection. Tests confirm she has COVID-19term·key, and she is admitted to a hospital unit. During hospitalization, she is accompanied by a multidisciplinary team. The course of the disease is irregular, and in periods of greater stability, she manifests a desire to return home. The team is sensitive to these wishes and family members are mobilized to plan a possible return home. Given the restrictions during the pandemic’s 2nd wave, family members communicate with Mrs. M. via video call. In one of these conversations, she expresses her willingness to confess and speak openly about her death. The medical team convenes a family conference to discuss advanced care planning. She verbalizes: “I don’t want to be a burden for my family... I know that death is coming, and I don’t want to suffer.” [sic]. Given this manifestation, she returns home, thus respecting Mrs. M.’s preferences. The minimum safety conditions are ensured, with the agreement of the care teams and family. The home team stipulates pleasurable activities and ensures family visits through the bedroom window (since it is on the ground floor) with the use of intercoms. Faced with a worsening condition, Mrs. M. refuses to return to the hospital. This information is shared with her children. Mrs. M. asks to see her grandchildren through the window. She shares her decisions with her children, says goodbye, and reviews guidelines about her end-of-life wishes.
This case refers to the opposite model, including the following attributes regarding the preparation for death: awareness and preparation for death through interactions between the patient, family, and health team, as well as acceptance of death with a plan for the dying process.
3.7. Operative Definition The concept of death unpreparednessterm·dom is defined as a transition in which the processes of information, communicationterm·dom, and relationship between the dying person, family, and HCPterm·dom are compromised. This process anticipates a lack of awareness about preparing for death and difficulty accepting the loss. Often the dying person and their family are not included in the EoL decision-making process. The key components of the concept include uncertainty and unpredictability given the virus’ unknown behavior, the rapid decline generating separation distress, and the incapacity to fulfill wishes and death preferences, determining changes to farewell dying rituals. This transition often evolves in two opposite ways: (1) post-traumatic growth and death acceptance, or (2) a misadjusted loss process with a high risk of prolonged griefterm·key.
The constant use of military metaphors and harsh language in medicine should be discarded since they fundamentally reinforce fear, stigma, and anxiety [ 67 ]. Given this effect and because metaphors are pervasive in human cognition and behavior, we picked an ecological metaphor to emphasize the caring, healing, and humanizing dimensions of healthcare. For better understanding, we use the dandelion symbolism to represent the concept of death unpreparednessterm·dom (see Figure 2 ). Dandelions are renowned for their capacity to flourish in difficult environments. Like dandelions, human beings can access their inner fortitude, endure life’s trials, and overcome adversity. In various cultures, dandelions are a potent symbol of fortitude, hope, determination, and the capacity to surmount challenges due to their remarkable resilience. However, when bioecological domains (personal, relational, or contextual factors) behave as obstacles, some negative consequences emerge, particularly related to worse bereavement outcomes. After a sudden “hurricane”, like a pandemic, some dandelion seeds collapse, but others survive, land, and grow, typically when the environmental conditions are favorable (e.g., support of others). By embracing the dandelion’s symbolism, we can develop an appreciation for these tenacious blossoms and their potent bioecological message of fortitude in the face of adversity, such as a pandemic.
Conceptual representation of death unpreparednessterm·dom due to a pandemic scenario.
4. Discussion This concept analysisterm·key demonstrates that the unpreparednessterm·dom for death during COVID-19term·key is conditioned by individual, relational, and contextual aspects. Non-preparedness for death is related to a state in which an individual or a community is not ready psychologically, emotionally, or spiritually to deal with death and loss. Before COVID-19term·key, this concept was coped with differently [ 26 ]. COVID-19term·key has drastically changed daily life in different ways, exposing major weaknesses around the world [ 68 , 69 ] and generating uncertainties in patients, families, caregivers, professionals, and the community itself. This implied changes in how they perceive, experience, and prepare for death and dying [ 70 , 71 ].
Before COVID-19term·key, death preparednessterm·dom was conceptualized as a transition process facilitated by communicationterm·dom with a healthcare provider, which leads to awareness and/or acceptance of end-of-life, as evidenced by the implementation of a plan [ 19 ]. After COVID-19term·key, the measures quickly imposed to face the disease’s uncertainty constrained communicationterm·dom between patients/families and healthcare professionalsterm·dom and made it impossible to implement a plan, thereby changing the concept of death preparednessterm·dom [ 72 ].
The concept of uncertainty in illnessterm·dom refers to the cognitive processes through which individuals interpret events associated with illness and derive meaning from them. This concept is characterized by the inability to ascertain the significance of illness-related events, which occurs when decision-makers are unable to definitively assign value to objects or events, or accurately predict outcomes [ 73 , 74 ]. This theory encompasses information obtained from the field of nursing as well as other disciplines. It focuses on clinical phenomena seen in clinical settings and aims to explain the process of assigning meaning to the experience of illness [ 73 ]. This lack of preparedness can impose negative consequences for people who are dying and their family/friends who have to deal with EoL issues and with loss and griefterm·key.
Not being prepared for death is a potential problem for all persons involved, implying psychosocial consequences, such as stress, anxiety, depression, and fear [ 33 , 46 , 50 ], and the consequences of death, such as prolonged griefterm·key symptoms [ 33 , 47 , 55 ]. The evidence indicates new ways of communicationterm·dom, compassionate professional support, and effective remote communicationterm·dom [ 40 , 47 , 51 , 52 , 53 , 55 , 57 , 64 ].
Enhancing familial relationships is unlikely to significantly extend a patient’s lifespan, but it may enhance their overall quality of life. Improving communicationterm·dom within a pandemic might potentially alleviate the emotional strainterm·dom experienced by both impacted families and healthcare professionalsterm·dom. It is essential to encourage open and compassionate conversations about EoL matters, to provide support in coping with the emotional and spiritual aspects of dying, and to guarantee that patients’ wishes are respected.
All the experience gathered about death and dying with COVID-19term·key should be a lesson for the future, of health professionals, health managers, families, informal caregivers, and the general community.
4.1. Study Limitations A limitation of using Walker and Avant’s approach [ 28 ] is the absence of a specific strategy suggested for delineating the applications of the concept. Nevertheless, the use of a comprehensive literature review in our study mitigated this constraint.
There are diverse cultural aspects surrounding death and dying, and different ways to grieve around the world. This makes it difficult to describe a normalized idea about attitudes and behaviors regarding bereavement. By excluding articles written in Chinese that refer to experience on the topic, we excluded experiences from the epicenter of COVID-19term·key. Only a few of the available articles were focused on affected people. Furthermore, we did not assess the methodologic quality of the articles (i.e., heterogenous samples; incomplete information, and low evidence level) nor did we estimate interrater reliability using the kappa statistic.
Notwithstanding these limitations, the present analysis can help develop a wide language that encompasses the concept. By basing the constructed cases in this analysis on real-world scenarios, a greater degree of realism was achieved.
4.2. Implications for Practice HCPsterm·dom have a crucial and significant role in delivering both health and psychological care during a pandemic. Enhancing communicationterm·dom and involving families in care choices are crucial strategies for mitigating the trauma often associated with death experiences [ 32 , 47 , 55 ]. The intent is to ensure the secure organization of family visits in healthcare settings. In cases where physical visits are not feasible, alternative methods of remote communicationterm·dom should be employed to connect families and loved ones. These communicationterm·dom methods should also support collaborative efforts among healthcare teams, families, and patients [ 40 , 44 , 63 ].
Despite restrictions, HCPsterm·dom should explore families’ ways of finding meaningful connections and of saying goodbye [ 40 , 48 ], promoting active family engagement to advocate wishes/preferences, and attending unfinished business [ 3 , 55 , 57 ].
Additional investment is required to enhance the availability of customized bereavement support services to effectively address the varied needs and backgrounds of those who have experienced loss. This includes the provision of culturally sensitive and crisis/contextually competent care, as well as the implementation of group-based support programs that cater to individuals with common experiences and traits. To proactively engage communities and increase knowledge of available support choices, it is recommended that information on griefterm·key and bereavement services be provided [ 45 , 75 , 76 ].
The promotion of self-care and reflection, along with the provision of psychological support, is crucial within healthcare teams [ 3 ]. To address this need, we recommend the development of training programs focused on mental health promotion and resilience skills [ 41 ].
5. Conclusions In summary, COVID-19term·key brought new challenges for emotional, physical, and spiritual resources affecting the preparedness for deathterm·dom. Death unpreparednessterm·dom emerged as a transition and a process characterized by uncertainty and unpredictability throughout the disease, generating separation distress and incapacity to manage existential issues to assure a good death. This transition may manifest in two contrasting outcomes: (1) post-traumatic development and acceptance of death, or (2) a maladaptive grieving process with a heightened susceptibility to extended suffering. It is essential to embrace strategies capable of providing emotional and spiritual support in the dying process and respect patients’ wishes, namely in catastrophic scenarios. In this sense, disaster management training will equip HCPsterm·dom to discuss EoL priorities and the dying process with patients suddenly affected by a life-threatening infectious illness; to inform patients’ families of their deaths; and to ensure patients are well-informed about the EoL, if applicable. Lessons learned from COVID-19term·key should be present in similar events with a comparable impact to minimize their consequences.
Supplementary Materials The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/healthcare12020188/s1 , Table S1. Characteristics of the studies included in the review (n = 34).
Click here for additional data file.
Author Contributions Conceptualization, C.C., A.Q. and C.L.; methodology, C.C., A.Q., M.A.D. and C.L.; validation, C.C., A.Q. and C.L.; formal analysis, C.C., M.A.D., A.Q., A.R., J.V., C.S. and C.L.; investigation, C.C., M.A.D., A.Q., A.R., J.V., C.S. and C.L.; resources, C.C., M.A.D., A.Q., A.R., J.V. and C.L; data curation, C.L.; writing—original draft preparation, C.C., M.A.D., A.Q., A.R., J.V. and C.L.; writing—review and editing, A.Q. and C.L; visualization, C.C., M.A.D., A.Q., A.R., J.V. and C.L.; supervision, C.L.; project administration, C.L. All authors have read and agreed to the published version of the manuscript.
Institutional Review Board Statement Not applicable.
Informed Consent Statement Not applicable.
Data Availability Statement All data generated or analyzed during this study are included in this article.
Conflicts of Interest The authors declare no conflict of interest. The funders had no role in the design of the study, in the collection, analyses, or interpretation of data, in the writing of the manuscript, or in the decision to publish the results.
Funding Statement This work was supported by FCT—Fundação para a Ciência e a Tecnologia, I.P. (UIDB/05704/2020 and UIDP/05704/2020) and by the Scientific Employment Stimulus—Institutional Call—[ https://doi.org/10.54499/CEECINST/00051/2018/CP1566/CT0012 , accessed on 30 December 2023].
Footnotes References Associated Data Supplementary Materials Click here for additional data file.
Data Availability Statement All data generated or analyzed during this study are included in this article.