Relating Introspective Accuracy to Individual Differences in Brain Structure

Fleming, Weil, Nagy, Dolan, Rees · Science · 2010 · neuroscience · 10.1126/science.1191883 · record Fleming2010-relating-introspective-accuracy-to-individua
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Where this record's text came from. faceted 2026-08 by reading the locally held text (xml); every evidence string verified as an exact substring of that text before merging. Claim relations is empty as a finding, not an omission: this Science report cites all prior work by bracketed numeral only (e.g. '( 16 - 18 )', '( 11 )'), so nowhere in the article text does it relate its claim to a NAMED prior study, and rule 7 forbids inferring a relation from a bare citation. method is recorded as structural-mri because the study used voxel-based morphometry and diffusion tensor imaging, not functional MRI; no term in the suggested method list covers structural neuroimaging, and labelling it 'fmri' would be false. Spacing inside the XML-derived text ('d’ and B roc', '( A roc )') is the source's own and was copied exactly. 2026-08-12 and 2026-08-15 schema-0.3 passes: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
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Other fields define these differently the same word, defined another way in another discipline
confidence 5 fields

Tags on this paper

Every tag the record carries, each linking to every other paper in the corpus that carries it. A tag appears here whether or not its words occur in the article — the spans below are only the ones a sentence in this paper licenses. Of the 16 concept tags on this paper, none is grounded in a quoted sentence. All carry the tagger's gloss of what the term means in this paper, which is not something the article can license.
metacognitive sensitivity introspective A roc B roc d’ Type II receiver operating characteristic anterior prefrontal cortex gray matter volume fractional anisotropy diffusion tensor imaging genu of the corpus callosum staircase procedure inferior temporal gyrus confidence dorsolateral prefrontal cortex test-retest reliability anterior prefrontal cortex supports introspective accuracy by carrying out second-order operations that integrate supramodal perceptual information with the decision output, thereby linking performance to confidence metacognitive ability depends not only on local prefrontal grey matter but on the integrity of the reciprocal fibre projections running into and out of that region metacognitive ability ratings of confidence overall brain size and gender fractional anisotropy of white matter objective task performance receiver operating characteristic (Type II ROC) analysis Type II receiver operating characteristic (ROC) curves correlation Pearson’s r coefficient of determination / model fit test-retest (split-half) reliability multiple-comparison correction corrected for multiple comparisons nuisance covariates in a regression model regressors of no interest signal-detection sensitivity and criterion d’ and c Pearson correlation multiple comparisons correction coefficient of determination receiver operating characteristic neuroimaging
Method, as described: structural-mri

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second readingalternativesan independent re-reading of a facet, recorded whether or not it agrees
relation to other workclaim_relationshow this paper stands to another: agrees, contradicts, extends, qualifies
claim typeclaim_typethe shape of the claim: existence, mechanism, method, critique, prediction, null
concept edgeconcept_edgesan asserted relation between two concepts, with the sentence asserting it
content tagcontent_tagsa finding, definition, quantity, statistic or variable named in the paper
controlcontrolsan experiment run to eliminate a rival explanation
limitationlimitationswhat the paper says its evidence cannot support
mechanismmechanismshow the reported effect is said to come about
methodmethodhow the paper produced its evidence
object of studyobject_of_studywhat the paper is about — the thing it investigates
phenomenonphenomenonthe effect or regularity under study
sensesensesa distinct use of a term, quoted where the paper fixes it

The paper

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Every tag on this page

alternatives 1 · claim_relations 3 · claim_type 1 · concept_edges 9 · content_tags 50 · controls 1 · limitations 7 · mechanisms 7 · method 1 · object_of_study 1 · phenomenon 1 · senses 5

Relations on this page carry a quotation for the claim. Where a relation was separately evidenced — and so tested against the vocabulary for its type — the row says so; none of 9 relations here carry that mark. The rest are the tagger’s reading of the sentence quoted beside them.

facettagfieldconf.whose words
object_of_studyIndividual differences in metacognitive sensitivity - how well a person's confidence tracks their own correctness - and whether those differences sit in brain structure.
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object_of_studythe paper's words
claim_typeexistence
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claim_typethe paper's words
phenomenonmetacognitive sensitivity
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phenomenonthe paper's words
methodneuroimaging
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also in: neuroimaging
methodthe paper's words
mechanismsmechanisms
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mechanisms[0]the tagger's words
mechanismsmechanisms
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mechanisms[1]the tagger's words
mechanismsHolding objective performance constant by staircasing difficulty per participant isolates metacognitive variation from perceptual variation
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mechanisms[2]the tagger's words
mechanismsType II ROC turns trial-by-trial confidence ratings into a single individual-level number, which is what makes a structural correlation possible at all
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mechanisms[3]the tagger's words
mechanismsAnterior prefrontal cortex is proposed as the site because it performs second-order operations on internally generated information, which is what metacognition requires
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mechanisms[4]the tagger's words
mechanismsThe white matter result is predicted from the grey matter one rather than found independently: if the region matters, its connections should too
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mechanisms[5]the tagger's words
mechanismsThe tract implicated carries fibres to and from exactly the prefrontal regions identified in the grey matter analysis, which is what makes the two results one result
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mechanisms[6]the tagger's words
limitationsThe design is correlational and cannot establish that the brain-structure/metacognition covariation is causal.
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what this limits: the structure-metacognition relationship: AS WITH ANY CORRELATIONAL METHOD, WE CANNOT ESTABLISH WHETHER THE COVARIATION ... REFLECTS A CAUSAL ROLE
limitations[0]the tagger's words
limitationsThe absence of structural correlates for objective performance and confidence bias may be an artefact of a design that deliberately minimised variability in those measures.
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what this limits: the null results for objective performance and confidence bias, which the design produced: OUR DESIGN DELIBERATELY MINIMISING VARIABILITY IN BOTH d' AND B_roc IN ORDER TO ISOLATE THE NEURAL CORRELATES OF INTROSPECTIVE ABILITY
limitations[1]the tagger's words
limitationsThe authors state plainly that the method cannot establish causation
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duplicate of: limitations[0] · what this limits: the same scope as limitations[0] - the method cannot establish causation
limitations[2]the tagger's words
limitationsThirty-two participants, for whole-brain structural correlations with a behavioural trait
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what this limits: the whole-brain structural analysis: WE STUDIED 32 HEALTHY HUMAN PARTICIPANTS, for correlations between grey matter volume and a behavioural trait
limitations[3]the tagger's words
limitationsThe design deliberately suppressed variance in performance and confidence bias, so the absence of structural correlates for those may be a consequence of the design rather than a finding
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duplicate of: limitations[1] · what this limits: the same scope as limitations[1] - the absence of structural correlates for d' and B_roc is a consequence of suppressing their variance on purpose
limitations[4]the tagger's words
limitationsThe left-hemisphere homologue and a second temporal cluster did not survive whole-brain correction and are reported in supplementary tables
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what this limits: the laterality of the finding: the homologous left anterior prefrontal region DID NOT SURVIVE CORRECTION FOR MULTIPLE COMPARISONS ACROSS THE BRAIN VOLUME
limitations[5]the tagger's words
limitationsWhether the anatomy is innate or the trace of experience is left open, and the two have very different implications
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what this limits: any developmental or trait reading of the anatomy: OUR PRESENT FINDINGS MAY REFLECT INNATE DIFFERENCES IN ANATOMY, OR ALTERNATIVELY REFLECT THE EFFECTS OF EXPERIENCE AND LEARNING
limitations[6]the tagger's words
controlscontrol analyses re-running the structural correlation while holding stimulus contrast - the staircase's converged value - constant
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eliminates: PERCEPTUAL ability as the confound behind an apparently INTROSPECTIVE one: a good perceiver's staircase settles at low contrast, so grey-matter correlates of metacognitive accuracy could be correlates of seeing well · outcome: held
controls[0]0.95the tagger's words
sensesmetacognitive ability - as an INDIVIDUAL-level trait: one number per person, which is the only level at which a structural correlation can be computed
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senses[0]1.0the tagger's words
sensesconfidence - as a TRIAL-level rating: what participants report after each decision, and the raw material rather than the measure
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senses[1]1.0the tagger's words
sensesmetacognition - sensitivity (A roc): how well confidence separates correct from incorrect, the quantity of interest
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senses[2]1.0the tagger's words
sensesmetacognition - bias (B roc): the tendency to use high or low confidence overall, which is a different thing and was checked to be uncorrelated
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senses[3]1.0the tagger's words
sensesperformance - objective (d’): how accurate the perceptual decisions were, deliberately held near constant so it cannot explain the result
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senses[4]1.0the tagger's words
alternativesclaim_type: existence
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a second reading reaching the same value. Recorded: existence — note: a second reading reaching the same value from a different sentence. Not applied - a person decides.
alternatives.claim_typethe tagger's words
claim_relationssupports → lesion studies showing deficits in subjective report after anterior prefrontal damage
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claim_relations[0]the tagger's words
claim_relationssupports → theta-burst TMS work showing metacognitive sensitivity can be impaired while performance is spared
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claim_relations[1]the tagger's words
claim_relationsextends → the body of work linking individual differences in language, decision making and memory to healthy brain anatomy
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claim_relations[2]the tagger's words
concept_edgesEVIDENCE CORRECTED (RE-GROUNDED) · A roc —distinct-from→ B roc
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EVIDENCE CORRECTED: RE-GROUNDED. The old span named neither parameter. This sentence names both and states that the separation was BUILT INTO THE DESIGN - variability in d' and B roc was deliberately minimised 'in order to isolate' the neural correlates of A roc. — strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but gray matter did not correlate with d' or with overall confidence (B roc); distinct-from is loose.
also in: A roc · B roc
concept_edges[2]the tagger's words
concept_edgesEVIDENCE CORRECTED (RE-GROUNDED) · A roc —distinct-from→ d’
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EVIDENCE CORRECTED: RE-GROUNDED. Same sentence as [2], and for the same reason: the design deliberately minimised variability in d' in order to isolate A roc, which is a stronger ground for a distinction than an observed difference would be. — strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but A roc and task performance were UNCORRELATED; distinct-from rests on a null correlation.
also in: A roc · d’
concept_edges[3]the tagger's words
concept_edgesfractional anisotropy —part-of→ diffusion tensor imaging
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strength of the relation: 1
concept_edges[6]the tagger's words
concept_edgesstaircase procedure —operationalised-as→ d’
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strength of the relation: 0.9 Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span links staircase convergence to perceptual ability; operationalised-as d' is loose.
concept_edges[8]the tagger's words
concept_edgesinferior temporal gyrus —contrasted-with→ anterior prefrontal cortex
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strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the inferior temporal gyrus showed a NEGATIVE correlation beside the primary positive one; contrasted-with is loose.
concept_edges[9]the tagger's words
concept_edgesdorsolateral prefrontal cortex —causes→ metacognitive sensitivity
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strength of the relation: 0.8
concept_edges[10]the tagger's words
concept_edgesintrospective —same-as→ metacognitive sensitivity
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strength of the relation: 1
concept_edges[11]the tagger's words
concept_edgesA roc —distinct-from→ B roc
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strength of the relation: 1 · note: RE-GROUNDS another row of this record: the old span named ONE endpoint. Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the design minimised variability in d' and B roc to isolate A roc; distinct-from is loose.
also in: A roc · B roc
concept_edges[14]0.9the tagger's words
concept_edgesA roc —distinct-from→ d’
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strength of the relation: 1 · note: RE-GROUNDS another row of this record: the old span named ONE endpoint. Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span explains a null structural result by the design; distinct-from is loose.
also in: A roc · d’
concept_edges[15]0.9the tagger's words
content_tagsreceiver operating characteristic (Type II ROC) analysis
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content_tags.statistics[0]the tagger's words
content_tagscorrelation
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also in: correlation
content_tags.statistics[1]the tagger's words
content_tagscoefficient of determination / model fit
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content_tags.statistics[2]the tagger's words
content_tagstest-retest (split-half) reliability
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content_tags.statistics[3]the tagger's words
content_tagsmultiple-comparison correction
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content_tags.statistics[4]the tagger's words
content_tagsnuisance covariates in a regression model
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content_tags.statistics[5]the tagger's words
content_tagssignal-detection sensitivity and criterion
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content_tags.statistics[6]the tagger's words
content_tagsPearson correlation
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content_tags.statistics[7]the tagger's words
content_tagstest-retest reliability
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content_tags.statistics[8]the tagger's words
content_tagsmultiple comparisons correction
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content_tags.statistics[9]the tagger's words
content_tagscoefficient of determination
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content_tags.statistics[10]the tagger's words
content_tagsreceiver operating characteristic
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content_tags.statistics[11]the tagger's words
content_tagsIndividual metacognitive accuracy varied widely even though objective task performance was held constant, and the two measures were unrelated.
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content_tags.findings[0]the tagger's words
content_tagsMetacognitive accuracy is stable within a person, as shown by split-half test-retest agreement.
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content_tags.findings[1]the tagger's words
content_tagsGrey matter volume in right anterior prefrontal cortex (BA 10) predicted how accurate a person's introspective judgements were.
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content_tags.findings[2]the tagger's words
content_tagsThat prefrontal grey matter effect was specific to metacognition: the same region's volume tracked neither perceptual sensitivity nor overall confidence bias.
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content_tags.findings[3]the tagger's words
content_tagsLeft inferior temporal gyrus grey matter showed the opposite, negative relationship with metacognitive sensitivity.
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content_tags.findings[4]the tagger's words
content_tagsWhite matter integrity in the genu of the corpus callosum, which carries anterior prefrontal fibres, also scaled with metacognitive accuracy.
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content_tags.findings[5]the tagger's words
content_tagsmetacognitive ability varied widely across people while objective performance was held constant, and the two were uncorrelated
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content_tags.findings[6]the tagger's words
content_tagsthe individual differences were stable across a split-half check
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content_tags.findings[7]the tagger's words
content_tagsmetacognitive ability correlated with grey matter volume in right anterior prefrontal cortex, surviving whole-brain correction
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content_tags.findings[8]the tagger's words
content_tagsthat same grey matter did not correlate with objective performance or with confidence bias
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content_tags.findings[9]the tagger's words
content_tagswhite matter integrity in the genu of the corpus callosum also tracked metacognitive ability
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content_tags.findings[10]the tagger's words
content_tagsleft inferior temporal gyrus showed the opposite, a negative structural correlation
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content_tags.findings[11]the tagger's words
content_tagsThe anterior prefrontal grey-matter and FA correlations held when controlling for task parameters, which themselves showed no correlations.
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content_tags.findings[12]the tagger's words
content_tagsmetacognitive ability
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content_tags.definitions[1]the tagger's words
content_tagsfractional anisotropy
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content_tags.definitions[3]the tagger's words
content_tagsmetacognitive sensitivity
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content_tags.definitions[4]the tagger's words
content_tagsmetacognitive ability
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content_tags.definitions[5]the tagger's words
content_tagsA roc
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also in: A roc
content_tags.definitions[6]the tagger's words
content_tagsfractional anisotropy
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content_tags.definitions[7]the tagger's words
content_tagsfractional anisotropy
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content_tags.variables[2]the tagger's words
content_tagsratings of confidence
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content_tags.variables[3]the tagger's words
content_tagsoverall brain size and gender
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content_tags.variables[5]the tagger's words
content_tagsmetacognitive ability
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content_tags.variables[7]the tagger's words
content_tagsgray matter volume
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content_tags.variables[8]the tagger's words
content_tagsfractional anisotropy of white matter
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content_tags.variables[9]the tagger's words
content_tagsoverall brain size and gender
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content_tags.variables[10]the tagger's words
content_tagsobjective task performance
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content_tags.variables[11]the tagger's words
content_tags32 — number of healthy human participants scanned and tested
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content_tags.quantities[0]the tagger's words
content_tags71% — the accuracy level at which each participant's perceptual difficulty was held by staircasing
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content_tags.quantities[1]the tagger's words
content_tagsmean R 2 = 0.97 ± 0.023 — goodness of fit of the Type II ROC model to individual participants' confidence data
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content_tags.quantities[2]the tagger's words
content_tagsA roc = 0.55 – 0.75 — range of individual metacognitive accuracy scores against a 70-74% constant objective performance range
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content_tags.quantities[3]the tagger's words
content_tagsr = 0.69, P = 0.00001 — split-half test-retest reliability of the A roc metacognitive measure
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content_tags.quantities[4]the tagger's words
content_tagst max = 4.8 — peak voxel statistic for the grey matter correlation with metacognitive ability in BA 10
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content_tags.quantities[5]the tagger's words
content_tags32 healthy human participants — the whole sample for a whole-brain structural analysis
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content_tags.quantities[6]the tagger's words
content_tags71% — the accuracy each participant was staircased to, so performance could not explain the result
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content_tags.quantities[7]the tagger's words
content_tagsA roc = 0.55 – 0.75 — the spread of metacognitive ability across individuals
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content_tags.quantities[8]the tagger's words
content_tagsr = 0.69, P = 0.00001 — split-half stability of the individual measure
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content_tags.quantities[9]the tagger's words
content_tagsmean R 2 = 0.97 ± 0.023 — fit of the ROC model to participants' confidence data
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content_tags.quantities[10]the tagger's words

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