Late maturation of backward masking in auditory cortex

Mattingly, Donell, Rosen · Journal of Neurophysiology · 2018 · neuroscience · 10.1152/jn.00114.2018 · record Mattingly2018-late-maturation-of-backward-masking-in-audit
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Where this record's text came from. faceted 2026-08 by reading the locally held text (html); every evidence string verified as an exact substring of that text before merging. Claim type is 'mechanism' because the paper's stated result is what drives cortical masking (suppressed signal-evoked firing plus reduced dynamic range) and why juveniles are masked more; an 'existence' reading is also available from 'This study is the first to assess whether backward masking of tone detection occurs at the level of primary auditory cortex for standard, onset-responsive neurons'. The facets cannot capture the paper's methodological argument about analysis windows - it contrasts a narrow tone-only window (ToneWin) with a whole-trial window (TrialWin) and reports that the longer window better matches human psychophysical threshold shifts, which is a distinct secondary contribution about how to build a neurometric. The inhibition-timing account offered for the developmental difference is explicitly speculative in the text and so was not recorded as a claim. Citation parentheses carry internal spaces from the PMC extraction and are quoted exactly. 2026-08-13 and 2026-08-14 schema-0.3 passes: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
How to read this page. The article itself is not reproduced here — this paper is not cleared for redistribution, so what follows is the tag layer alone. The evidence sentences are withheld with the article. The table at the foot lists every tag the record carries; each row names the facet it belongs to, and the whose words column says whether the tag records the paper's own wording or the tagger's sentence about the paper. Every tag links to each other paper in the corpus carrying it. The machine-readable edition of the same thing is the TEI file beside this one, where the tags live in standOff, and the article is at its publisher via the link below. When we have changed our mind. Some entries in the table begin with a word in capitals and the reason for it. EVIDENCE CORRECTED — the finding still stands, but we had quoted the wrong sentence from the paper, and the quotation has been replaced with the right one. RETRACTED — the entry itself was wrong; it stays on the page, marked, with the reason, rather than being deleted. WITHDRAWN AND REPLACED — the entry was wrong, and a corrected version of it appears in the entries below. Each mark carries its own reason, in brackets, because the reasons differ from one entry to the next. An entry we have WITHDRAWN is removed from this page and kept in the record, with its reason. A line reading Audit and a date is a later re-reading of the entry against its whole sentence: DOUBTFUL means it was kept, and the reason says what is loose about it. Quotation marks inside the tagger's sentence. Where a tag is the tagger's own sentence, a phrase in quotation marks inside it is borrowed from the paper — the tagger's wording around it is not. The paper's own sentence is the evidence quote for that row; on this page it is withheld with the article, and the article is at its publisher. Nothing inside quotation marks anywhere on this page is ours: if it is quoted, it is the paper's. Whose words a concept carries. A concept entry records a term the paper itself uses, so the term, the sense given for it, and its evidence are the paper's own words, quoted where the paper fixes them. This is the opposite of a sense entry in the tag table, which is the tagger's sentence about how the paper uses a term. Where a concept entry could not be grounded in the paper's words, the entry says so on its own row.
Other fields define these differently the same word, defined another way in another discipline
principal component analysis 5 fields · integration 3 fields · population 3 fields · perception 3 fields · threshold 2 fields · anesthesia 2 fields · and 6 more →

Tags on this paper

Every tag the record carries, each linking to every other paper in the corpus that carries it. A tag appears here whether or not its words occur in the article — the spans below are only the ones a sentence in this paper licenses. Of the 46 concept tags on this paper, 4 are grounded in a quoted sentence. All carry the tagger's gloss of what the term means in this paper, which is not something the article can license.
backward masking forward masking masker tone noise signal threshold detection dynamic range suppression firing baseline neurometric window ToneWin TrialWin psychophysical perception juvenile adult children development maturation ACx cortex inferior colliculus cochlear nucleus inhibition excitation latency population cell neuron pooling lower envelope variability anesthesia urethane awake temporal integration speech BF multiunit correlation spontaneous Inhibition evoked by the masker arrives with a shorter latency than excitation, so it can reach back and suppress the response to the tone that preceded it. In immature cortex the inhibitory response to the masker is larger and slower to decay, so it truncates more of the preceding excitatory tone response and amplifies firing-rate suppression in juveniles. Juveniles integrate over a longer listening window, which pulls more masker-driven firing into the comparison baseline, shrinking the dynamic range and raising masked thresholds. Unrefined inhibition in cortex or in presynaptic regions lets an off-frequency noise masker suppress juvenile responses more than adult ones. ToneWin and TrialWin analysis windows encoding time window threshold shift pooling neurometric lower envelope principle masker level tone level age group masked tone threshold shift tone-evoked firing rate suppression Mann-Whitney U test Mann-Whitney U -tests for across-unit comparisons Wilcoxon signed-rank test The Wilcoxon signed-rank test Spearman rank correlation Spearman’s nonparametric rank correlation Fisher's exact test Fisher’s exact tests of elevation differences ANCOVA (nonparametric ranked mixed model) bootstrap confidence interval principal component analysis sorted into single (SU) or multiunits (MU) on the basis of spike shape and principal component analysis standard error variances are reported as SE percentiles / box plot summary electrophysiology

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relation to other workclaim_relationshow this paper stands to another: agrees, contradicts, extends, qualifies
claim typeclaim_typethe shape of the claim: existence, mechanism, method, critique, prediction, null
concept edgeconcept_edgesan asserted relation between two concepts, with the sentence asserting it
conceptconceptsan idea the paper works with, quoted where the paper uses it
content tagcontent_tagsa finding, definition, quantity, statistic or variable named in the paper
contributioncontributionwhat the paper claims to add
controlcontrolsan experiment run to eliminate a rival explanation
limitationlimitationswhat the paper says its evidence cannot support
mechanismmechanismshow the reported effect is said to come about
methodmethodhow the paper produced its evidence
object of studyobject_of_studywhat the paper is about — the thing it investigates
phenomenonphenomenonthe effect or regularity under study
research questionresearch_questionthe question the paper sets itself
sensesensesa distinct use of a term, quoted where the paper fixes it
transfertransfersa method or concept carried in from another field
unrecordable relationunhoused_relationsa relation the paper asserts that this vocabulary cannot express, with the reason

The paper

The full text is not reproduced here. This article is not cleared for redistribution, so the page carries the tag layer only. Its evidence sentences are withheld; the grounding status remains with each tag, and the article itself is at https://doi.org/10.1152/jn.00114.2018. The reading view exists for the papers whose licence permits it.

Every tag on this page

alternatives 3 · claim_relations 9 · claim_type 1 · concept_edges 11 · concepts 4 · content_tags 85 · contribution 1 · controls 1 · limitations 10 · mechanisms 8 · method 1 · object_of_study 1 · phenomenon 1 · research_question 1 · senses 15 · transfers 5 · unhoused_relations 1

Relations on this page carry a quotation for the claim. Where a relation was separately evidenced — and so tested against the vocabulary for its type — the row says so; none of 11 relations here carry that mark. The rest are the tagger’s reading of the sentence quoted beside them.

facettagfieldconf.whose words
object_of_studythe cortical basis of auditory backward masking, and whether its unusually long maturation in children is visible in cortical responses
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object_of_studythe paper's words
research_questionwhether standard onset-responsive cortical neurons show backward masking at all, and whether juveniles show more of it than adults
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research_questionthe paper's words
contributionbackward masking is present in ordinary cortical neurons, arises from both suppressed tone firing and a reduced dynamic range, and is larger in juveniles - mainly through the suppression
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contributionthe paper's words
claim_typemechanism
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claim_typethe paper's words
phenomenonauditory backward masking
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phenomenonthe paper's words
methodelectrophysiology
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methodthe paper's words
mechanismsmechanisms
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mechanisms[0]the tagger's words
mechanismsmechanisms
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mechanisms[1]the tagger's words
mechanismsmechanisms
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mechanisms[2]the tagger's words
mechanismsmechanisms
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mechanisms[3]the tagger's words
mechanismsmasking arises from a reduction of the signal response together with a higher comparative baseline, which narrows the dynamic range available for detection
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mechanisms[4]1.0the tagger's words
mechanismsand a shorter latency for inhibition than for excitation lets the later masker suppress the earlier tone, which also explains why a suppressed masker response masks less
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mechanisms[5]1.0the tagger's words
mechanismsso the cortical effect may be inherited from earlier regions, with cortex possibly adding to it by reducing rebound excitation
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mechanisms[6]0.8the tagger's words
mechanismsand the immature version is attributed to inhibition that decays more slowly and summates more in young neurons
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mechanisms[7]0.8the tagger's words
limitationsRecordings were made under anesthesia, which complicates extrapolation to psychophysics.
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what this limits: the comparison with psychophysics only: ANESTHESIA IS ONE CONCERN IN EXTENDING OUR NEURAL RESPONSES TO PSYCHOPHYSICAL COMPARISONS
limitations[0]the tagger's words
limitationsIt is unknown whether the nervous system actually reads out only the narrow tone-response window the analysis assumes.
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what this limits: the readout assumption behind every ToneWin result: IT IS UNKNOWN WHETHER THE NERVOUS SYSTEM IS ANALYZING ACTIVITY ONLY WITHIN THIS WINDOW
limitations[1]the tagger's words
limitationsThe population neurometric pools every recorded cell, which is both its strength and its weakness.
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what this limits: every population-neurometric result: IT POOLS INFORMATION ACROSS ALL CELLS TO MAKE A DECISION FOR OR AGAINST TONE DETECTION - stated by the authors as strength and limitation
limitations[2]the tagger's words
limitationsIncluding non-responsive neurons should degrade the pooled neurometric, and whether that degradation is age-dependent is unknown.
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what this limits: the absolute level of the neurometric, and the age comparison it feeds: PERFORMANCE ... SHOULD BE REDUCED BY INCORPORATING RESPONSES FROM NONRESPONSIVE NEURONS, BUT WHETHER THIS EFFECT WOULD VARY ACROSS AGE is unknown
limitations[3]the tagger's words
limitationsSingle units and multiunits were pooled because multiunits dominated the dataset.
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what this limits: any claim resting on single-unit resolution: Quotation withheld
limitations[4]the tagger's words
limitationsit is unknown whether the nervous system analyses only the narrow window, and finding out would require trial-by-trial mapping of activity onto behavioral choice
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what this limits: the same scope as limitations[1] - the analysis window is the experimenter's, not shown to be the nervous system's
limitations[5]1.0the tagger's words
limitationsthe population neurometric pools every cell, which is both its strength and its limitation, and sits against the rival principle that only the most sensitive neurons matter
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what this limits: the same scope as limitations[2] - the pooled neurometric
limitations[6]1.0the tagger's words
limitationsand because every neuron was tested at its own best frequency, the pooled measure is optimistic in a way the paper spells out
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what this limits: the absolute performance of the neurometric, which is optimistic by construction: BECAUSE ALL NEURONS ... WERE PRESENTED WITH STIMULI AT BF, OUR NEUROMETRIC DOES NOT REFLECT THE SITUATION WHERE A DOWNSTREAM INTEGRATOR NEURON WOULD ALSO RECEIVE INPUT FROM other cells
limitations[7]1.0the tagger's words
limitationsanesthesia is named as a concern for the comparison with psychophysics, with urethane chosen to keep the cortex closest to the awake state
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what this limits: the same scope as limitations[0] - the psychophysical comparison, with urethane chosen deliberately
limitations[8]1.0the tagger's words
limitationsand the authors' own earlier null on the best neurons suggests the difference may lie in how the information is used rather than in how it is encoded
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what this limits: the interpretation of the age effect: the authors' own earlier study OBSERVED NO AGE DIFFERENCE IN THE THRESHOLDS OF THE BEST NEURONS, so the difference may be in pooling rather than in single-neuron sensitivity
limitations[9]1.0the tagger's words
transfersThe two-alternative forced-choice detection procedure and threshold-shift logic of human masking experiments is carried over to single-unit spike counts as a neurometric, so that neural thresholds can be compared directly with psychometric ones.
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transfers[0]the tagger's words
transfersthe masked-versus-unmasked threshold comparison, reproduced in the neurometric so the two can be put side by side
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transfers[1]1.0the tagger's words
transfersthe encoding time window as an explicit parameter, and the requirement to choose one
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transfers[2]1.0the tagger's words
transferspopulation coding, which assumes that all active neurons contribute to perception, against the lower envelope principle, which assumes that perception is driven by the most sensitive neurons
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transfers[3]1.0the tagger's words
transfersthe relative-timing-of-inhibition account of masking
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transfers[4]1.0the tagger's words
controlsa SECOND analysis window spanning the entire trial, beside the assumption-bearing one
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eliminates: the choice of time window as the driver of the result - a window chosen to capture an expected effect will find it · outcome (stated by the tagger, no quotation): held
controls[0]0.9the tagger's words
conceptsmasker
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also in: masker
concepts[2]the paper's words
conceptsthreshold
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also in: threshold
concepts[6]the paper's words
conceptsdynamic range
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also in: dynamic range
concepts[8]the paper's words
conceptsjuvenile
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also in: juvenile
concepts[18]the paper's words
unhoused_relationsMUs → analysis
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AN ANALYST DECISION WITH ITS REASON GIVEN: because multiunits dominated the data set, all single units and multiunits were POOLED for analysis. The composition is 15 SU / 27 MU in adults and 10 SU / 30 MU in juveniles, so the pooling decision is load-bearing for every comparison that follows. No edge type records a choice the analysts made.
unhoused_relations[0]the tagger's words
sensesTHE ANALYSIS WINDOW IS A CHOICE, AND THE REASONS ARE GIVEN BEFORE THE RESULT: a brief window isolates backward masking uncontaminated by forward masking, a longer one includes the masker response because behavioral reaction times fall well after masker onset
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senses[0]1.0the tagger's words
sensesAND THE TWO WINDOWS GIVE DIFFERENT NUMBERS: about 18 to 43 dB of threshold shift in the longer window against 13 to 16 dB in the narrow one, with human psychophysics at 20 to 35 dB
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senses[1]1.0the tagger's words
sensesTHE CORRECT WINDOW CANNOT BE DETERMINED FROM THIS DATA: it would require trial-by-trial mapping of neural activity onto behavioral choice, and IN LIEU OF SUCH DATA the longer window is chosen for two stated reasons
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senses[2]1.0the tagger's words
senseswith both reasons named - detection is measured against the masker alone, and the behavioral reaction time falls well after the masker begins
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senses[3]1.0the tagger's words
sensesA STRENGTH AND A LIMITATION IN ONE SENTENCE: the population neurometric pools every cell, which sits against the rival principle that perception is driven by the most sensitive neurons alone
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senses[4]1.0the tagger's words
sensesAND THE DIRECTION OF THE OWN BIAS IS SPELLED OUT: because every neuron was tested at its own best frequency, the pooled measure omits the poorly tuned cells a real integrator would receive, and would perform worse if they were included
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senses[5]1.0the tagger's words
sensesTHE VARIABILITY IS ITSELF A POINT OF CORRESPONDENCE: masked thresholds are quite variable IN CONCURRENCE WITH the psychophysical data, where more measures per participant are needed than for forward masking
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senses[6]1.0the tagger's words
sensesA CORRELATE THAT IS NOT THE CAUSE, SAID PLAINLY: masking correlated with tone-evoked suppression but could occur in its absence, and thus was not the sole driver
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senses[7]1.0the tagger's words
sensesTHE METHOD IS ALIGNED TO THE LITERATURE IT WILL BE COMPARED WITH: stimuli were delivered monaurally to parallel the majority of psychophysical backward masking studies
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senses[8]1.0the tagger's words
sensesand the inclusion rule is set by the perceptual phenomenon rather than by the recording - only units responding reliably to short tones, because backward masking is reliable only for short tones
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senses[9]1.0the tagger's words
sensesA POOLING DECISION JUSTIFIED BY THE COMPOSITION OF THE SAMPLE: single and multi-units were pooled BECAUSE multi-units dominated the data set
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senses[10]1.0the tagger's words
sensesTHE anesthetic IS JUSTIFIED BY MECHANISM RATHER THAN WAVED AWAY: urethane acts modestly on multiple receptor systems and allows desynchronised cortical activity, unlike ketamine or pentobarbital
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senses[11]1.0the tagger's words
sensesAND THE AUTHORS' OWN EARLIER NULL COMPLICATES THE STORY: no age difference in the thresholds of the BEST neurons, suggesting juveniles and adults may not equivalently ACCESS the same sensory information
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senses[12]1.0the tagger's words
senseswith the developmental interpretation flagged as conditional - IF juveniles integrate over a longer window, they would experience larger dynamic range differences
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senses[13]1.0the tagger's words
sensesand the locus argued from where the phenomenon is and is not found - backward masking appears in the inferior colliculus but not the auditory nerve or cochlear nucleus, and cannot be peripheral because the signal precedes the masker
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senses[14]1.0the tagger's words
alternativesclaim_type: mechanism
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a second reading reaching the same value. Recorded: mechanism — note: a second reading reaching the same value from a different sentence. Not applied - a person decides.
alternatives.claim_typethe tagger's words
alternativesmethod: neurometric thresholds computed in two analysis windows - one containing only the tone response, one containing the masker response as well
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a second reading DIFFERING from the recorded value. Recorded: electrophysiology — note: a second reading, verbatim-verified, disagreeing with the value on the record. Not applied - a person decides.
alternatives.methodthe tagger's words
alternativesphenomenon: backward masking - a higher threshold for a short tone when a masker follows it than for the same tone in silence
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a second reading DIFFERING from the recorded value. Recorded: auditory backward masking — note: a second reading, verbatim-verified, disagreeing with the value on the record. Not applied - a person decides.
alternatives.phenomenonthe tagger's words
claim_relationsextends → Brosch et al. 1998 (backward masking in very-long-latency cortical cells)
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claim_relations[0]the tagger's words
claim_relationsbuilds-on → Hartley et al. 2000; Huyck and Wright 2018 (developmental psychophysics of backward masking)
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claim_relations[1]the tagger's words
claim_relationsbuilds-on → Rosen et al. 2010 (the authors' own gerbil ACx modulation-detection study)
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claim_relations[2]the tagger's words
claim_relationsextends → the one prior cortical report, which examined only cells with responses beyond 150 ms rather than standard onset responses
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claim_relations[3]1.0the tagger's words
claim_relationsconfirms → the human finding that backward masked thresholds remain immature into adolescence, now in cortical responses
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claim_relations[4]1.0the tagger's words
claim_relationsdistinguishes-from → forward masking, whose relationship between masker level and threshold shift is tight where this one is not
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differs in: THE AXIS IS MEASUREMENT VARIABILITY, AND THE CONSEQUENCE IS A SAMPLE-SIZE REQUIREMENT. 'Quotation withheld.' The two paradigms differ in how much data a conclusion costs - so a null in backward masking is weaker evidence than the same null in forward masking, at equal n.
claim_relations[5]1.0the tagger's words
claim_relationsbuilds-on → the inferior colliculus account in which inhibition arriving earlier than excitation lets a later masker suppress an earlier tone
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claim_relations[6]1.0the tagger's words
claim_relationsqualifies → its own population measure, which pools cells that a real downstream integrator would not receive in the same proportions
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differs in: THE AXIS IS WHICH CELLS THE POPULATION MEASURE POOLS. 'Quotation withheld.' The measure is not wrong - it describes a population no downstream neuron ever receives, because the recording selected for best frequency. A sampling decision that changes what the number is a number OF.
claim_relations[7]1.0the tagger's words
claim_relationsreconciles → an earlier null on the best neurons, by proposing that the difference lies in access to the information rather than its encoding
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claim_relations[8]1.0the tagger's words
concept_edgesforward masking —distinct-from→ backward masking
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strength of the relation: 1
concept_edges[5]1.0the tagger's words
concept_edgesbackward masking —part-of→ inferior colliculus
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strength of the relation: 1 · note: THE LOCUS ARGUED FROM WHERE IT IS AND IS NOT FOUND: present in the inferior colliculus, absent in the auditory nerve and cochlear nucleus, and impossible peripherally because the signal precedes the masker 2026-08-20 the project re-read worst chars/edge queue): WRONG-TYPE - the sentence says backward masking has been DEMONSTRATED IN the inferior colliculus. That is a location where a phenomenon was recorded, not a part-whole relation - backward masking is not part of a brain region. Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but backward masking 'HAS BEEN DEMONSTRATED IN' the inferior colliculus; part-of is loose.
concept_edges[6]1.0the tagger's words
concept_edgescochlear nucleus —contrasted-with→ inferior colliculus
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strength of the relation: 1 · note: re-read worst chars/edge queue): SOUND - the sentence does contrast them: forward but NOT backward masking in the cochlear nucleus, BUT backward masking demonstrated in the inferior colliculus. Both endpoints named, contrast explicit, type correct. KEEP.
concept_edges[7]1.0the tagger's words
concept_edgesACx —causes→ perception
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status: the paper's own words: suggesting that · strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span says ACx activity relates to masked signal perception; causes is loose.
also in: ACx · perception
concept_edges[10]1.0the tagger's words
concept_edgesjuvenile —contrasted-with→ adult
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strength of the relation: 1 · note: greater tone-firing suppression AND larger threshold shifts, at both single-cell and population levels Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span is cut before the juvenile-adult contrast is stated.
also in: juvenile · adult
concept_edges[11]1.0the tagger's words
concept_edgesmasker —operationalised-as→ noise
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strength of the relation: 1 · note: a 500 ms noise at 30% bandwidth centerd on the neuron's own best frequency, immediately after a 10 ms tone
also in: masker · noise
concept_edges[17]1.0the tagger's words
concept_edgesbackward masking —part-of→ ACx
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strength of the relation: 1 · note: the first assessment for STANDARD, ONSET-RESPONSIVE neurons rather than the long-latency subset of the one prior study Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the study shows backward masking OCCURS AT the level of primary auditory cortex; part-of is loose.
also in: backward masking · ACx
concept_edges[19]1.0the tagger's words
concept_edgesanesthesia —distinct-from→ psychophysical
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strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span raises anesthesia as a concern for psychophysical comparison; distinct-from is loose.
concept_edges[24]1.0the tagger's words
concept_edgescortex —causes→ suppression
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strength of the relation: 0.8 · note: the cortical effect may be INHERITED from earlier regions, with cortex possibly magnifying it by reducing rebound excitation Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span says masked responses may be inherited from earlier regions; causes is loose.
also in: cortex · suppression
concept_edges[30]0.8the tagger's words
concept_edgesTrialWin —contrasted-with→ ToneWin
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strength of the relation: 1 · note: AND THE TWO WINDOWS GIVE DIFFERENT NUMBERS: 18-43 dB against 13-16 dB in adults, with human psychophysics at 20-35 dB
also in: TrialWin · ToneWin
concept_edges[36]1.0the tagger's words
concept_edgestone —contrasted-with→ masker
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strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its span and kept, but tone-alone and tone+noise functions were compared; contrasted-with is loose.
also in: tone · masker
concept_edges[48]1.0the tagger's words
content_tagsMann-Whitney U test
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content_tags.statistics[0]the tagger's words
content_tagsWilcoxon signed-rank test
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content_tags.statistics[1]the tagger's words
content_tagsSpearman rank correlation
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content_tags.statistics[2]the tagger's words
content_tagsFisher's exact test
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content_tags.statistics[3]the tagger's words
content_tagsANCOVA (nonparametric ranked mixed model)
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content_tags.statistics[4]the tagger's words
content_tagsbootstrap
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also in: bootstrap
content_tags.statistics[5]the tagger's words
content_tagsconfidence interval
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content_tags.statistics[6]the tagger's words
content_tagsprincipal component analysis
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content_tags.statistics[7]the tagger's words
content_tagsstandard error
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content_tags.statistics[8]the tagger's words
content_tagspercentiles / box plot summary
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about this quote: This quote ends with the stray word 'To', the first word of the next sentence. It is not trimmed, because the quote without it occurs more than once in the paper's text and could not be tied to one place. The claim is carried by the sentence before 'To'.
content_tags.statistics[9]the tagger's words
content_tagsprincipal component analysis
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content_tags.statistics[10]1.0the tagger's words
content_tagscorrelation
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also in: correlation
content_tags.statistics[11]1.0the tagger's words
content_tagsMost auditory cortex neurons required a louder tone to be detected when a noise masker immediately followed the tone, demonstrating backward masking in ordinary onset-responsive cortical cells.
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content_tags.findings[0]the tagger's words
content_tagsCortical backward masking arises from two things at once: the masker suppresses the tone-evoked response, and it raises the baseline so that the dynamic range available for detecting the tone shrinks.
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content_tags.findings[1]the tagger's words
content_tagsJuvenile units showed significantly larger masked threshold shifts than adult units under both analysis windows.
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content_tags.findings[2]the tagger's words
content_tagsTone-evoked firing was suppressed by the masker more strongly in juveniles than in adults under both analysis windows.
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content_tags.findings[3]the tagger's words
content_tagsThe masker-induced reduction of dynamic range was the same size in juveniles and adults, so the age difference in masking was not driven by dynamic range.
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content_tags.findings[4]the tagger's words
content_tagsUnits that gave no response at all to the noise alone still showed significant masked threshold shifts, so a response to the masker is not required for backward masking.
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content_tags.findings[5]the tagger's words
content_tagsPopulation threshold shifts computed over the whole trial (~18-43 dB in adults) matched human psychophysical backward-masking shifts far better than shifts computed over the narrow tone window (~13-16 dB).
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content_tags.findings[6]the tagger's words
content_tagsIn units that did respond to the noise alone, the preceding tone significantly suppressed the noise-evoked firing, i.e. forward masking occurred alongside backward masking in both age groups.
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content_tags.findings[7]the tagger's words
content_tagsPooling all units into a population neurometric also produced larger threshold shifts for juveniles than for adults under both windows.
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content_tags.findings[8]the tagger's words
content_tagsWithin the narrow tone window, the loss of dynamic range predicted the masked threshold shift only in juveniles, suggesting juveniles rely more on dynamic range for detection.
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content_tags.findings[9]the tagger's words
content_tagsThe masker caused only a small delay in first-spike latency in both age groups.
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content_tags.findings[10]the tagger's words
content_tagsbackward masking has a longer maturational trajectory than many other auditory percepts, and its neural correlates are not well described at any developmental stage
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content_tags.findings[11]1.0the tagger's words
content_tagsAND THE TWO WINDOWS GIVE DIFFERENT ANSWERS: neural threshold shifts match human psychophysics better when the longer window is used
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content_tags.findings[12]1.0the tagger's words
content_tagsTHE ANALYSIS WINDOW IS A CHOICE, WITH THE REASONS GIVEN BEFORE THE RESULT: one isolates backward masking uncontaminated by forward masking, the other includes the masker response
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content_tags.findings[13]1.0the tagger's words
content_tagsTHE LOCUS ARGUED FROM WHERE IT IS AND IS NOT FOUND: present in inferior colliculus, absent in auditory nerve and cochlear nucleus, impossible peripherally because the signal precedes the masker
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content_tags.findings[14]1.0the tagger's words
content_tagswith variability itself taken as INDICATIVE of central contributions, being greater in backward than forward masking
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content_tags.findings[15]1.0the tagger's words
content_tagsthe area was chosen because inactivating it impairs temporal discrimination and because human imaging ties it to conscious masked detection
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content_tags.findings[16]1.0the tagger's words
content_tagsjuvenile neurons showed both greater tone-firing suppression and larger threshold shifts, at single-cell and population levels
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content_tags.findings[17]1.0the tagger's words
content_tagsA POOLING DECISION JUSTIFIED BY THE COMPOSITION OF THE SAMPLE: single and multi-units pooled BECAUSE the multi-units dominated
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content_tags.findings[18]1.0the tagger's words
content_tagsTHE METHOD IS ALIGNED TO THE LITERATURE IT WILL BE COMPARED WITH: monaural delivery, to parallel the majority of psychophysical studies
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content_tags.findings[19]1.0the tagger's words
content_tagsAND THE INCLUSION RULE IS SET BY THE PERCEPT: only units responding reliably to short tones, because backward masking is reliable only for short tones
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content_tags.findings[20]1.0the tagger's words
content_tagsthe masker was a 500 ms noise at 30% bandwidth centerd on each neuron's own best frequency
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content_tags.findings[21]1.0the tagger's words
content_tagsthis is the first assessment of backward masking in STANDARD onset-responsive cortical neurons, and both coding elements contribute
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content_tags.findings[22]1.0the tagger's words
content_tagswith the two elements dissociating across development - larger suppression in juveniles but no difference in dynamic range reduction
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content_tags.findings[23]1.0the tagger's words
content_tagsTHE anesthetic IS JUSTIFIED BY MECHANISM: urethane acts modestly on several receptor systems and allows desynchronised activity closer to the awake state
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content_tags.findings[24]1.0the tagger's words
content_tagsTHE VARIABILITY IS ITSELF A POINT OF CORRESPONDENCE with the psychophysics, unlike the tight relationship seen for forward masking
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content_tags.findings[25]1.0the tagger's words
content_tagsA CORRELATE THAT IS NOT THE CAUSE, SAID PLAINLY: suppression correlated with masking but could occur in its absence
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content_tags.findings[26]1.0the tagger's words
content_tagsa shorter latency for inhibition than excitation lets the later masker suppress the earlier tone, and predicts the negative correlation observed
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content_tags.findings[27]1.0the tagger's words
content_tagsso the cortical effect may be inherited from earlier regions, with cortex possibly magnifying it
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content_tags.findings[28]1.0the tagger's words
content_tagsthe backgrounds were chosen deliberately to match how a listener's two thresholds are compared
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content_tags.findings[29]1.0the tagger's words
content_tagsand the dynamic range correlates with masking ONLY in juveniles and ONLY in the narrow window
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content_tags.findings[30]1.0the tagger's words
content_tagsTHE CORRECT WINDOW CANNOT BE DETERMINED FROM THIS DATA: it would need trial-by-trial mapping of activity onto behavioral choice
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content_tags.findings[31]1.0the tagger's words
content_tagsIN LIEU OF SUCH DATA the longer window is chosen for two named reasons - the comparison is against the masker alone, and the reaction time falls after masker onset
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content_tags.findings[32]1.0the tagger's words
content_tags18-43 dB of shift in the longer window against 13-16 dB in the narrow one, with human psychophysics at 20-35 dB
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content_tags.findings[33]1.0the tagger's words
content_tagsA STRENGTH AND A LIMITATION IN ONE SENTENCE, with the rival lower-envelope principle named
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content_tags.findings[34]1.0the tagger's words
content_tagsAND THE DIRECTION OF THE OWN BIAS SPELLED OUT: testing every neuron at its own best frequency makes the pooled measure optimistic
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content_tags.findings[35]1.0the tagger's words
content_tagsAND THE AUTHORS' OWN EARLIER NULL COMPLICATES IT: no age difference in the best neurons, so the difference may be in ACCESS rather than encoding
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content_tags.findings[36]1.0the tagger's words
content_tagschildren LISTEN LATE with respect to a signal, and may be integrating over a longer window than adults
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content_tags.findings[37]1.0the tagger's words
content_tagswith the developmental interpretation flagged as conditional - IF juveniles integrate longer, they WOULD see larger dynamic range differences
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content_tags.findings[38]1.0the tagger's words
content_tagsand the slow maturation attributed to inhibition, which decays more slowly and summates more in young neurons
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content_tags.findings[39]1.0the tagger's words
content_tagsthe differential signal suppression could contribute to the large age-related threshold differences seen in psychophysical backward masking, about 25-dB differences around age 9 and still about 10-dB differences by age 15
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content_tags.findings[40]1.0the tagger's words
content_tagsand the whole point is stated plainly - detection deficits correlate with problems in speech processing
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content_tags.findings[41]1.0the tagger's words
content_tagsToneWin and TrialWin analysis windows
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content_tags.definitions[2]the tagger's words
content_tagsdynamic range
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also in: dynamic range
content_tags.definitions[3]the tagger's words
content_tagsencoding time window
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content_tags.definitions[4]the tagger's words
content_tagsthreshold shift
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content_tags.definitions[5]the tagger's words
content_tagspooling neurometric
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content_tags.definitions[6]the tagger's words
content_tagslower envelope principle
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content_tags.definitions[7]the tagger's words
content_tagsbackward masking
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content_tags.definitions[8]1.0the tagger's words
content_tagswindow
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also in: window
content_tags.definitions[9]1.0the tagger's words
content_tagslower envelope
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content_tags.definitions[10]1.0the tagger's words
content_tagsToneWin
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also in: ToneWin
content_tags.definitions[11]1.0the tagger's words
content_tagsBF
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also in: BF
content_tags.definitions[12]0.8the tagger's words
content_tagsmasker level
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also in: masker level
content_tags.variables[0]the tagger's words
content_tagstone level
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also in: tone level
content_tags.variables[1]the tagger's words
content_tagsage group
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also in: age group
content_tags.variables[2]the tagger's words
content_tagsmasked tone threshold shift
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content_tags.variables[3]the tagger's words
content_tagstone-evoked firing rate suppression
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content_tags.variables[4]the tagger's words
content_tagsthreshold
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also in: threshold
content_tags.variables[9]1.0the tagger's words
content_tagsdynamic range
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also in: dynamic range
content_tags.variables[10]1.0the tagger's words
content_tagssuppression
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also in: suppression
content_tags.variables[11]1.0the tagger's words
content_tagswindow
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also in: window
content_tags.variables[12]1.0the tagger's words
content_tagsn = 16 adults, n = 18 juveniles — gerbils in each age group and their postnatal-day ranges
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content_tags.quantities[0]the tagger's words
content_tagsn = 42 / n = 40 — cortical units recorded in adults and in juveniles
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content_tags.quantities[1]the tagger's words
content_tagsToneWin: P = 0.003; TrialWin: P = 0.013 — Fisher's exact test of elevation showing greater masking in juveniles than adults
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content_tags.quantities[2]the tagger's words
content_tagsToneWin: adult, 15, 13, and 16 dB; juvenile, 21, 19, and 15 dB; TrialWin: adult, 18, 43, and 43 dB; juvenile, 28, 48, and 48 dB — population neurometric threshold shifts at low, mid and high masker levels for each age group and window
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content_tags.quantities[3]the tagger's words
content_tags~20–35 dB — human psychophysical backward-masked threshold shifts under comparable masking parameters, the benchmark for the neural shifts
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content_tags.quantities[4]the tagger's words
content_tags65% — detection criterion on the neurometric function used to define a unit's tone detection threshold
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content_tags.quantities[5]the tagger's words
content_tags>50% — share of units showing masked threshold shifts of about 12-15 dB even under the narrow tone window
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content_tags.quantities[6]the tagger's words
content_tags1,000 — bootstrap resamples drawn per tone level to compute percent-correct detection
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content_tags.quantities[7]the tagger's words
content_tags13–16 dB — the adult threshold shift measured in the narrow window against 18-43 dB in the longer one - the same neurons, two windows, and only the second matches the 20-35 dB of human psychophysics
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content_tags.quantities[8]1.0the tagger's words
content_tags50% of trials — the response reliability a unit had to reach to be recorded at all, a selection set by the perceptual phenomenon rather than by the recording
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content_tags.quantities[9]1.0the tagger's words
content_tags~25-dB — the human age difference in backward masked thresholds around age nine, still about 10 dB by fifteen
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content_tags.quantities[10]1.0the tagger's words

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