Late maturation of backward masking in auditory cortex — TEI-tagged view

Mattingly, Donell, Rosen · 2018 · neuroscience · doi:10.1152/jn.00114.2018 · full text at the source · TEI xml · tagged edition · index · concepts · authors
Where this record's text came from. faceted 2026-08 by reading the locally held text (html); every evidence string verified as an exact substring of that text before merging. Claim type is 'mechanism' because the paper's stated result is what drives cortical masking (suppressed signal-evoked firing plus reduced dynamic range) and why juveniles are masked more; an 'existence' reading is also available from 'This study is the first to assess whether backward masking of tone detection occurs at the level of primary auditory cortex for standard, onset-responsive neurons'. The facets cannot capture the paper's methodological argument about analysis windows - it contrasts a narrow tone-only window (ToneWin) with a whole-trial window (TrialWin) and reports that the longer window better matches human psychophysical threshold shifts, which is a distinct secondary contribution about how to build a neurometric. The inhibition-timing account offered for the developmental difference is explicitly speculative in the text and so was not recorded as a claim. Citation parentheses carry internal spaces from the PMC extraction and are quoted exactly. 2026-08-13 and 2026-08-14 schema-0.3 passes: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
Other fields define these differently the same word, defined another way in another discipline
principal component analysis 5 fields · integration 3 fields · population 3 fields · perception 3 fields · threshold 2 fields · anesthesia 2 fields · and 6 more →
Tags on this paper every tag the record carries, whether or not the words occur in the text below — a number is how many papers in the corpus carry that tag; a tag with no number is unique to this paper
backward masking3 forward masking masker2 tone4 noise17 signal7 threshold21 detection8 dynamic range4 suppression4 firing4 baseline6 neurometric window ToneWin TrialWin psychophysical perception10 juvenile adult children6 development5 maturation2 ACx cortex9 inferior colliculus7 cochlear nucleus6 inhibition17 excitation7 latency19 population15 cell3 neuron13 pooling4 lower envelope variability2 anesthesia14 urethane6 awake7 temporal4 integration8 speech5 BF4 multiunit4 correlation108 spontaneous6 electrophysiology110

Our tag layer for this paper

Cross-disciplinary analysis
content-tags & facets: phenomenon · claim-type · cross-domain-transfer · mechanism · claim-relation · replication-status · limitation — grounded in the full text
phenomenonauditory backward masking— “Perceptually, auditory backward masking manifests as higher thresholds for detection of a short signal followed by a masker than for the same signal in silence.”
claim-typemechanism— “Cortical masking was driven by a combination of suppressed responses to the signal and a reduced dynamic range available for signal detection in the presence of the masker.”
method — evidence— “We thus recorded firing responses from auditory cortex (ACx) in response to masked and unmasked sounds in juveniles compared with adults.”
object of study — evidence— “Speech perception relies on the accurate resolution of brief, successive sounds that change rapidly over time. Deficits in the perception of such sounds, indicated by a reduced ability to detect signals during auditory backward masking, strongly relate to language processing difficulties in children. Backward masking during normal development…
research question — evidence— “This study is the first to assess whether backward masking of tone detection occurs at the level of primary auditory cortex for standard, onset-responsive neurons, how it manifests, and whether it mirrors the prolonged development seen in children. Backward masking is the neural “detection” of a masked signal compared with the masker alone…
contribution — evidence— “In this study we have demonstrated that the onset responses of ACx neurons to short tones were clearly modulated by a subsequent masker. Neurometric thresholds shifted to higher tone levels in the presence of this masker. The higher thresholds seen during masking were attributable to a combination of suppressed firing to the tone and a…
transferfrom psychophysics / behavioural psychoacoustics: The two-alternative forced-choice detection procedure and threshold-shift logic of human masking experiments is carried over to single-unit spike counts as a neurometric, so that neural thresholds can be compared directly with psychometric ones.— “We presented our stimuli and analyzed our data with methods analogous to those used during behavioral detection experiments to best understand the neural responses that could underlie the perceptual phenomenon.”transfers[0]
transferfrom human psychoacoustics: the masked-versus-unmasked threshold comparison, reproduced in the neurometric so the two can be put side by side— “Our neurometric comparison used Noise-Alone-evoked firing and spontaneous firing as the backgrounds against which each threshold was determined to match perceptual measures. In psychophysical detection, listeners choose between alternatives of a masker with and without a tone, to yield a masked detection threshold. A separate choice between…transfers[1]
transferfrom signal detection neurometrics: the encoding time window as an explicit parameter, and the requirement to choose one— “Neurometric analysis requires the choosing of an appropriate encoding time window, defined as the window containing the response patterns contributing to the signal to be detected ( Panzeri et al. 2010 ). For these neurometric analyses, we employed two windows to test different aspects of masking. First, a brief analysis window encompassed…transfers[2]
transferfrom population coding theory: population coding, which assumes that all active neurons contribute to perception, against the lower envelope principle, which assumes that perception is driven by the most sensitive neurons— “A strength and limitation of the population neurometric used in the present study is that it pools information across all cells to make a decision for or against tone detection. In general, population coding assumes that all active neurons contribute to perception, whereas the lower envelope principle assumes that perception is driven by the…transfers[3]
transferfrom bat inferior colliculus physiology: the relative-timing-of-inhibition account of masking— “Mechanistically, forward masking is considered to involve a combination of synaptic depression, afterhyperpolarization, and inhibition ( Brosch and Schreiner 1997 ; Wehr and Zador 2005 ). A study of forward and backward masking in the bat inferior colliculus indicates that mechanisms involving the relative timing of inhibition and excitation…transfers[4]
mechanismInhibition evoked by the masker arrives with a shorter latency than excitation, so it can reach back and suppress the response to the tone that preceded it.— “Backward masking was attributable to fast inhibition, where a shorter latency for inhibition compared with excitation allowed inhibition evoked by the delayed masker to suppress the response to the earlier tone.”mechanisms[0]
mechanismIn immature cortex the inhibitory response to the masker is larger and slower to decay, so it truncates more of the preceding excitatory tone response and amplifies firing-rate suppression in juveniles.— “Thus a larger inhibitory response to the subsequent masker might differentially truncate a previous excitatory response to the tone in young neurons, magnifying tone-evoked firing rate suppression.”mechanisms[1]
mechanismJuveniles integrate over a longer listening window, which pulls more masker-driven firing into the comparison baseline, shrinking the dynamic range and raising masked thresholds.— “If juveniles integrate over a longer window than adults, they would experience larger dynamic range differences due to incorporating more firing activity from the masker.”mechanisms[2]
mechanismUnrefined inhibition in cortex or in presynaptic regions lets an off-frequency noise masker suppress juvenile responses more than adult ones.— “In juveniles, the differentially increased suppression in the presence of a noise masker that activates off-frequency neurons may be due to unrefined inhibition in cortex or in presynaptic regions.”mechanisms[3]
mechanismmasking arises from a reduction of the signal response together with a higher comparative baseline, which narrows the dynamic range available for detection— “This study is the first to assess whether backward masking of tone detection occurs at the level of primary auditory cortex for standard, onset-responsive neurons, how it manifests, and whether it mirrors the prolonged development seen in children. Backward masking is the neural “detection” of a masked signal compared with the masker alone…mechanisms[4]
mechanismand a shorter latency for inhibition than for excitation lets the later masker suppress the earlier tone, which also explains why a suppressed masker response masks less— “Mechanistically, forward masking is considered to involve a combination of synaptic depression, afterhyperpolarization, and inhibition ( Brosch and Schreiner 1997 ; Wehr and Zador 2005 ). A study of forward and backward masking in the bat inferior colliculus indicates that mechanisms involving the relative timing of inhibition and excitation…mechanisms[5]
mechanismso the cortical effect may be inherited from earlier regions, with cortex possibly adding to it by reducing rebound excitation— “Cortical masked responses, expressed as a reduction in tone-evoked firing, may thus be inherited from earlier brain regions. It remains possible that cortex further increases masking. In gerbil ACx, both tone-evoked afterhyperpolarizations and rebound firing were reduced in magnitude by a temporally overlapping masker ( Gay et al. 2014 ).…mechanisms[6]
mechanismand the immature version is attributed to inhibition that decays more slowly and summates more in young neurons— “An additional challenge to juvenile signal detection with backward maskers is the greater tone-evoked firing suppression shown in the present study. In addition to inefficient temporal integration, this differential signal suppression could contribute to the large age-related threshold differences seen in psychophysical backward masking…mechanisms[7]
extends Brosch et al. 1998 (backward masking in very-long-latency cortical cells)— “Both forward and backward masking are considered to involve central auditory regions, but backward masking has only been described in ACx for those cells with very long latency responses (>150 ms responses to a 100-ms tone; Brosch et al. 1998 ), distinct from the onset responsive neurons recorded in the present study.”claim_relations[0]
builds-on Hartley et al. 2000; Huyck and Wright 2018 (developmental psychophysics of backward masking)— “On the basis of psychophysical studies, children exhibit higher tone detection thresholds during backward masking than adults ( Hartley et al. 2000 ; Huyck and Wright 2018 ).”claim_relations[1]
builds-on Rosen et al. 2010 (the authors' own gerbil ACx modulation-detection study)— “In a previous study, we observed no age difference in the thresholds of the best neurons in gerbil ACx tuned to modulation detection, suggesting that juvenile and adult animals may not equivalently access the sensory information in these most sensitive neurons ( Rosen et al. 2010 ).”claim_relations[2]
extends the one prior cortical report, which examined only cells with responses beyond 150 ms rather than standard onset responses— “The neural mechanisms contributing to temporal masking, both backward and forward, have been attributed to central auditory regions, because temporal masking functions are not sufficiently explained by responses in the auditory periphery ( Plack and Oxenham 1998 ; Relkin and Turner 1988 ). Forward temporal masking, where the neural response…claim_relations[3]
confirms the human finding that backward masked thresholds remain immature into adolescence, now in cortical responses— “NEW & NOTEWORTHY In children, auditory detection of backward masked signals is immature well into adolescence, and…claim_relations[4]
distinguishes-from forward masking, whose relationship between masker level and threshold shift is tight where this one is not
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claim_relations[5]
builds-on the inferior colliculus account in which inhibition arriving earlier than excitation lets a later masker suppress an earlier tone
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claim_relations[6]
qualifies its own population measure, which pools cells that a real downstream integrator would not receive in the same proportions
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claim_relations[7]
reconciles an earlier null on the best neurons, by proposing that the difference lies in access to the information rather than its encoding
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claim_relations[8]
senseTHE ANALYSIS WINDOW IS A CHOICE, AND THE REASONS ARE GIVEN BEFORE THE RESULT: a brief window isolates backward masking uncontaminated by forward masking, a longer one includes the masker response because behavioral reaction times fall well after masker onset
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senses[0]
senseAND THE TWO WINDOWS GIVE DIFFERENT NUMBERS: about 18 to 43 dB of threshold shift in the longer window against 13 to 16 dB in the narrow one, with human psychophysics at 20 to 35 dB
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senses[1]
senseTHE CORRECT WINDOW CANNOT BE DETERMINED FROM THIS DATA: it would require trial-by-trial mapping of neural activity onto behavioral choice, and IN LIEU OF SUCH DATA the longer window is chosen for two stated reasons
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senses[2]
sensewith both reasons named - detection is measured against the masker alone, and the behavioral reaction time falls well after the masker begins
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senses[3]
senseA STRENGTH AND A LIMITATION IN ONE SENTENCE: the population neurometric pools every cell, which sits against the rival principle that perception is driven by the most sensitive neurons alone
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senses[4]
senseAND THE DIRECTION OF THE OWN BIAS IS SPELLED OUT: because every neuron was tested at its own best frequency, the pooled measure omits the poorly tuned cells a real integrator would receive, and would perform worse if they were included
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senses[5]
senseTHE VARIABILITY IS ITSELF A POINT OF CORRESPONDENCE: masked thresholds are quite variable IN CONCURRENCE WITH the psychophysical data, where more measures per participant are needed than for forward masking
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senses[6]
senseA CORRELATE THAT IS NOT THE CAUSE, SAID PLAINLY: masking correlated with tone-evoked suppression but could occur in its absence, and thus was not the sole driver
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senses[7]
senseTHE METHOD IS ALIGNED TO THE LITERATURE IT WILL BE COMPARED WITH: stimuli were delivered monaurally to parallel the majority of psychophysical backward masking studies
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senses[8]
senseand the inclusion rule is set by the perceptual phenomenon rather than by the recording - only units responding reliably to short tones, because backward masking is reliable only for short tones
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senses[9]
senseA POOLING DECISION JUSTIFIED BY THE COMPOSITION OF THE SAMPLE: single and multi-units were pooled BECAUSE multi-units dominated the data set
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senses[10]
senseTHE anesthetic IS JUSTIFIED BY MECHANISM RATHER THAN WAVED AWAY: urethane acts modestly on multiple receptor systems and allows desynchronised cortical activity, unlike ketamine or pentobarbital
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senses[11]
senseAND THE AUTHORS' OWN EARLIER NULL COMPLICATES THE STORY: no age difference in the thresholds of the BEST neurons, suggesting juveniles and adults may not equivalently ACCESS the same sensory information
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senses[12]
sensewith the developmental interpretation flagged as conditional - IF juveniles integrate over a longer window, they would experience larger dynamic range differences
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senses[13]
senseand the locus argued from where the phenomenon is and is not found - backward masking appears in the inferior colliculus but not the auditory nerve or cochlear nucleus, and cannot be peripheral because the signal precedes the masker
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senses[14]
controla SECOND analysis window spanning the entire trial, beside the assumption-bearing one — held — rules out the choice of time window as the driver of the result - a window chosen to capture an expected effect will find it
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controls[0]
differs inforward masking, whose relationship between masker level and threshold shift is tight where this one is not — THE AXIS IS MEASUREMENT VARIABILITY, AND THE CONSEQUENCE IS A SAMPLE-SIZE REQUIREMENT. 'masked thresholds are quite variable, in concurrence with psychophysical data: behaviorally, backward masking thresholds are highly variable, both within and across subjects; more threshold measures need to be gathered per participant than in forward masking to yield clear data.' The two paradigms differ in how much data a conclusion costs - so a null in backward masking is weaker evidence than the same null in forward masking, at equal n.
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claim_relations[5]
differs inits own population measure, which pools cells that a real downstream integrator would not receive in the same proportions — THE AXIS IS WHICH CELLS THE POPULATION MEASURE POOLS. 'Because all neurons in this study were presented with stimuli at BF, our neurometric does not reflect the situation where a downstream integrator neuron would also receive input from cells that were poorly tuned to the stimulus.' The measure is not wrong - it describes a population no downstream neuron ever receives, because the recording selected for best frequency. A sampling decision that changes what the number is a number OF.
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claim_relations[7]
edgeforward masking —distinct-from→ backward masking
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concept_edges[5]
auditbackward masking —part-of→ inferior colliculus — Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but backward masking 'HAS BEEN DEMONSTRATED IN' the inferior colliculus; part-of is loose.
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concept_edges[6]
notebackward masking —part-of→ inferior colliculus — THE LOCUS ARGUED FROM WHERE IT IS AND IS NOT FOUND: present in the inferior colliculus, absent in the auditory nerve and cochlear nucleus, and impossible peripherally because the signal precedes the masker 2026-08-20 the project re-read worst chars/edge queue): WRONG-TYPE - the sentence says backward masking has been DEMONSTRATED IN the inferior colliculus. That is a location where a phenomenon was recorded, not a part-whole relation - backward masking is not part of a brain region.
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concept_edges[6]
notecochlear nucleus —contrasted-with→ inferior colliculus — re-read worst chars/edge queue): SOUND - the sentence does contrast them: forward but NOT backward masking in the cochlear nucleus, BUT backward masking demonstrated in the inferior colliculus. Both endpoints named, contrast explicit, type correct. KEEP.
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concept_edges[7]
auditACx —causes→ perception — Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span says ACx activity relates to masked signal perception; causes is loose.
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concept_edges[10]
evidential statusACx —causes→ perception — the paper's own words: suggesting that
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concept_edges[10]
auditjuvenile —contrasted-with→ adult — Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span is cut before the juvenile-adult contrast is stated.
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concept_edges[11]
notejuvenile —contrasted-with→ adult — greater tone-firing suppression AND larger threshold shifts, at both single-cell and population levels
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concept_edges[11]
notemasker —operationalised-as→ noise — a 500 ms noise at 30% bandwidth centerd on the neuron's own best frequency, immediately after a 10 ms tone
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concept_edges[17]
auditbackward masking —part-of→ ACx — Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the study shows backward masking OCCURS AT the level of primary auditory cortex; part-of is loose.
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concept_edges[19]
notebackward masking —part-of→ ACx — the first assessment for STANDARD, ONSET-RESPONSIVE neurons rather than the long-latency subset of the one prior study
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concept_edges[19]
auditanesthesia —distinct-from→ psychophysical — Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span raises anesthesia as a concern for psychophysical comparison; distinct-from is loose.
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concept_edges[24]
auditcortex —causes→ suppression — Audit 2026-09-28: DOUBTFUL - read against its span and kept, but the span says masked responses may be inherited from earlier regions; causes is loose.
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concept_edges[30]
notecortex —causes→ suppression — the cortical effect may be INHERITED from earlier regions, with cortex possibly magnifying it by reducing rebound excitation
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concept_edges[30]
weightcortex —causes→ suppression — 0.8
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concept_edges[30]
noteTrialWin —contrasted-with→ ToneWin — AND THE TWO WINDOWS GIVE DIFFERENT NUMBERS: 18-43 dB against 13-16 dB in adults, with human psychophysics at 20-35 dB
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concept_edges[36]
audittone —contrasted-with→ masker — Audit 2026-09-28: DOUBTFUL - read against its span and kept, but tone-alone and tone+noise functions were compared; contrasted-with is loose.
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concept_edges[48]
outcome (stated by the tagger, no quotation)control — heldcontrols[0]
for which uselimitation — the comparison with psychophysics only: ANESTHESIA IS ONE CONCERN IN EXTENDING OUR NEURAL RESPONSES TO PSYCHOPHYSICAL COMPARISONS
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limitations[0]
for which uselimitation — the readout assumption behind every ToneWin result: IT IS UNKNOWN WHETHER THE NERVOUS SYSTEM IS ANALYZING ACTIVITY ONLY WITHIN THIS WINDOW
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limitations[1]
for which uselimitation — every population-neurometric result: IT POOLS INFORMATION ACROSS ALL CELLS TO MAKE A DECISION FOR OR AGAINST TONE DETECTION - stated by the authors as strength and limitation
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limitations[2]
for which uselimitation — the absolute level of the neurometric, and the age comparison it feeds: PERFORMANCE ... SHOULD BE REDUCED BY INCORPORATING RESPONSES FROM NONRESPONSIVE NEURONS, BUT WHETHER THIS EFFECT WOULD VARY ACROSS AGE is unknown
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limitations[3]
for which uselimitation — any claim resting on single-unit resolution: BECAUSE MUS DOMINATED THE DATA SET, ALL SUS AND MUS WERE POOLED FOR ANALYSIS
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limitations[4]
for which uselimitation — the same scope as limitations[1] - the analysis window is the experimenter's, not shown to be the nervous system's
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limitations[5]
for which uselimitation — the same scope as limitations[2] - the pooled neurometric
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limitations[6]
for which uselimitation — the absolute performance of the neurometric, which is optimistic by construction: BECAUSE ALL NEURONS ... WERE PRESENTED WITH STIMULI AT BF, OUR NEUROMETRIC DOES NOT REFLECT THE SITUATION WHERE A DOWNSTREAM INTEGRATOR NEURON WOULD ALSO RECEIVE INPUT FROM other cells
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limitations[7]
for which uselimitation — the same scope as limitations[0] - the psychophysical comparison, with urethane chosen deliberately
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limitations[8]
for which uselimitation — the interpretation of the age effect: the authors' own earlier study OBSERVED NO AGE DIFFERENCE IN THE THRESHOLDS OF THE BEST NEURONS, so the difference may be in pooling rather than in single-neuron sensitivity
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limitations[9]
replicationuntested
no type for thisMUs → analysis — AN ANALYST DECISION WITH ITS REASON GIVEN: because multiunits dominated the data set, all single units and multiunits were POOLED for analysis. The composition is 15 SU / 27 MU in adults and 10 SU / 30 MU in juveniles, so the pooling decision is load-bearing for every comparison that follows. No edge type records a choice the analysts made.
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unhoused_relations[0]
limitationRecordings were made under anesthesia, which complicates extrapolation to psychophysics.
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limitations[0]
limitationIt is unknown whether the nervous system actually reads out only the narrow tone-response window the analysis assumes.
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limitations[1]
limitationThe population neurometric pools every recorded cell, which is both its strength and its weakness.
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limitations[2]
limitationIncluding non-responsive neurons should degrade the pooled neurometric, and whether that degradation is age-dependent is unknown.
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limitations[3]
limitationSingle units and multiunits were pooled because multiunits dominated the dataset.
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limitations[4]
limitationit is unknown whether the nervous system analyses only the narrow window, and finding out would require trial-by-trial mapping of activity onto behavioral choice
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limitations[5]
limitationthe population neurometric pools every cell, which is both its strength and its limitation, and sits against the rival principle that only the most sensitive neurons matter
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limitations[6]
limitationand because every neuron was tested at its own best frequency, the pooled measure is optimistic in a way the paper spells out
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limitations[7]
limitationanesthesia is named as a concern for the comparison with psychophysics, with urethane chosen to keep the cortex closest to the awake state
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limitations[8]
limitationand the authors' own earlier null on the best neurons suggests the difference may lie in how the information is used rather than in how it is encoded
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limitations[9]
Content tags
content-observations: finding · quantity · variable · definition · key-term — grounded in the full text
findingMost auditory cortex neurons required a louder tone to be detected when a noise masker immediately followed the tone, demonstrating backward masking in ordinary onset-responsive cortical cells.
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content_tags.findings[0]
findingCortical backward masking arises from two things at once: the masker suppresses the tone-evoked response, and it raises the baseline so that the dynamic range available for detecting the tone shrinks.
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content_tags.findings[1]
findingJuvenile units showed significantly larger masked threshold shifts than adult units under both analysis windows.
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content_tags.findings[2]
findingTone-evoked firing was suppressed by the masker more strongly in juveniles than in adults under both analysis windows.
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content_tags.findings[3]
findingThe masker-induced reduction of dynamic range was the same size in juveniles and adults, so the age difference in masking was not driven by dynamic range.
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content_tags.findings[4]
findingUnits that gave no response at all to the noise alone still showed significant masked threshold shifts, so a response to the masker is not required for backward masking.
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content_tags.findings[5]
findingPopulation threshold shifts computed over the whole trial (~18-43 dB in adults) matched human psychophysical backward-masking shifts far better than shifts computed over the narrow tone window (~13-16 dB).
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content_tags.findings[6]
findingIn units that did respond to the noise alone, the preceding tone significantly suppressed the noise-evoked firing, i.e. forward masking occurred alongside backward masking in both age groups.
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content_tags.findings[7]
findingPooling all units into a population neurometric also produced larger threshold shifts for juveniles than for adults under both windows.
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content_tags.findings[8]
findingWithin the narrow tone window, the loss of dynamic range predicted the masked threshold shift only in juveniles, suggesting juveniles rely more on dynamic range for detection.
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content_tags.findings[9]
findingThe masker caused only a small delay in first-spike latency in both age groups.
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content_tags.findings[10]
findingbackward masking has a longer maturational trajectory than many other auditory percepts, and its neural correlates are not well described at any developmental stage
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content_tags.findings[11]
findingAND THE TWO WINDOWS GIVE DIFFERENT ANSWERS: neural threshold shifts match human psychophysics better when the longer window is used
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content_tags.findings[12]
findingTHE ANALYSIS WINDOW IS A CHOICE, WITH THE REASONS GIVEN BEFORE THE RESULT: one isolates backward masking uncontaminated by forward masking, the other includes the masker response
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content_tags.findings[13]
findingTHE LOCUS ARGUED FROM WHERE IT IS AND IS NOT FOUND: present in inferior colliculus, absent in auditory nerve and cochlear nucleus, impossible peripherally because the signal precedes the masker
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content_tags.findings[14]
findingwith variability itself taken as INDICATIVE of central contributions, being greater in backward than forward masking
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content_tags.findings[15]
findingthe area was chosen because inactivating it impairs temporal discrimination and because human imaging ties it to conscious masked detection
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content_tags.findings[16]
findingjuvenile neurons showed both greater tone-firing suppression and larger threshold shifts, at single-cell and population levels
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content_tags.findings[17]
findingA POOLING DECISION JUSTIFIED BY THE COMPOSITION OF THE SAMPLE: single and multi-units pooled BECAUSE the multi-units dominated
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content_tags.findings[18]
findingTHE METHOD IS ALIGNED TO THE LITERATURE IT WILL BE COMPARED WITH: monaural delivery, to parallel the majority of psychophysical studies
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content_tags.findings[19]
findingAND THE INCLUSION RULE IS SET BY THE PERCEPT: only units responding reliably to short tones, because backward masking is reliable only for short tones
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content_tags.findings[20]
findingthe masker was a 500 ms noise at 30% bandwidth centerd on each neuron's own best frequency
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content_tags.findings[21]
findingthis is the first assessment of backward masking in STANDARD onset-responsive cortical neurons, and both coding elements contribute
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content_tags.findings[22]
findingwith the two elements dissociating across development - larger suppression in juveniles but no difference in dynamic range reduction
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content_tags.findings[23]
findingTHE anesthetic IS JUSTIFIED BY MECHANISM: urethane acts modestly on several receptor systems and allows desynchronised activity closer to the awake state
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content_tags.findings[24]
findingTHE VARIABILITY IS ITSELF A POINT OF CORRESPONDENCE with the psychophysics, unlike the tight relationship seen for forward masking
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content_tags.findings[25]
findingA CORRELATE THAT IS NOT THE CAUSE, SAID PLAINLY: suppression correlated with masking but could occur in its absence
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content_tags.findings[26]
findinga shorter latency for inhibition than excitation lets the later masker suppress the earlier tone, and predicts the negative correlation observed
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content_tags.findings[27]
findingso the cortical effect may be inherited from earlier regions, with cortex possibly magnifying it
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content_tags.findings[28]
findingthe backgrounds were chosen deliberately to match how a listener's two thresholds are compared
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content_tags.findings[29]
findingand the dynamic range correlates with masking ONLY in juveniles and ONLY in the narrow window
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content_tags.findings[30]
findingTHE CORRECT WINDOW CANNOT BE DETERMINED FROM THIS DATA: it would need trial-by-trial mapping of activity onto behavioral choice
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content_tags.findings[31]
findingIN LIEU OF SUCH DATA the longer window is chosen for two named reasons - the comparison is against the masker alone, and the reaction time falls after masker onset
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content_tags.findings[32]
finding18-43 dB of shift in the longer window against 13-16 dB in the narrow one, with human psychophysics at 20-35 dB
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content_tags.findings[33]
findingA STRENGTH AND A LIMITATION IN ONE SENTENCE, with the rival lower-envelope principle named
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content_tags.findings[34]
findingAND THE DIRECTION OF THE OWN BIAS SPELLED OUT: testing every neuron at its own best frequency makes the pooled measure optimistic
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content_tags.findings[35]
findingAND THE AUTHORS' OWN EARLIER NULL COMPLICATES IT: no age difference in the best neurons, so the difference may be in ACCESS rather than encoding
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content_tags.findings[36]
findingchildren LISTEN LATE with respect to a signal, and may be integrating over a longer window than adults
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content_tags.findings[37]
findingwith the developmental interpretation flagged as conditional - IF juveniles integrate longer, they WOULD see larger dynamic range differences
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content_tags.findings[38]
findingand the slow maturation attributed to inhibition, which decays more slowly and summates more in young neurons
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content_tags.findings[39]
findingthe differential signal suppression could contribute to the large age-related threshold differences seen in psychophysical backward masking, about 25-dB differences around age 9 and still about 10-dB differences by age 15
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content_tags.findings[40]
findingand the whole point is stated plainly - detection deficits correlate with problems in speech processing
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content_tags.findings[41]
quantityn = 16 adults, n = 18 juveniles — gerbils in each age group and their postnatal-day ranges
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content_tags.quantities[0]
quantityn = 42 / n = 40 — cortical units recorded in adults and in juveniles
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content_tags.quantities[1]
quantityToneWin: P = 0.003; TrialWin: P = 0.013 — Fisher's exact test of elevation showing greater masking in juveniles than adults
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content_tags.quantities[2]
quantityToneWin: adult, 15, 13, and 16 dB; juvenile, 21, 19, and 15 dB; TrialWin: adult, 18, 43, and 43 dB; juvenile, 28, 48, and 48 dB — population neurometric threshold shifts at low, mid and high masker levels for each age group and window
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content_tags.quantities[3]
quantity~20–35 dB — human psychophysical backward-masked threshold shifts under comparable masking parameters, the benchmark for the neural shifts
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content_tags.quantities[4]
quantity65% — detection criterion on the neurometric function used to define a unit's tone detection threshold
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content_tags.quantities[5]
quantity>50% — share of units showing masked threshold shifts of about 12-15 dB even under the narrow tone window
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content_tags.quantities[6]
quantity1,000 — bootstrap resamples drawn per tone level to compute percent-correct detection
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content_tags.quantities[7]
quantity13–16 dB — the adult threshold shift measured in the narrow window against 18-43 dB in the longer one - the same neurons, two windows, and only the second matches the 20-35 dB of human psychophysics
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content_tags.quantities[8]
quantity50% of trials — the response reliability a unit had to reach to be recorded at all, a selection set by the perceptual phenomenon rather than by the recording
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content_tags.quantities[9]
quantity~25-dB — the human age difference in backward masked thresholds around age nine, still about 10 dB by fifteen
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content_tags.quantities[10]
variablemasker level (independent)
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content_tags.variables[0]
variabletone level (independent)
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content_tags.variables[1]
variableage group (independent)
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content_tags.variables[2]
variablemasked tone threshold shift (dependent)
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content_tags.variables[3]
variabletone-evoked firing rate suppression (dependent)
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content_tags.variables[4]
variablethreshold
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content_tags.variables[9]
variabledynamic range
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content_tags.variables[10]
variablesuppression
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content_tags.variables[11]
variablewindow
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content_tags.variables[12]
definitionToneWin and TrialWin analysis windows
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content_tags.definitions[2]
definitiondynamic range
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content_tags.definitions[3]
definitionencoding time window
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content_tags.definitions[4]
definitionthreshold shift
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content_tags.definitions[5]
definitionpooling neurometric
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content_tags.definitions[6]
definitionlower envelope principle
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content_tags.definitions[7]
definitionbackward masking
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content_tags.definitions[8]
definitionwindow
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content_tags.definitions[9]
definitionlower envelope
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content_tags.definitions[10]
definitionToneWin
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content_tags.definitions[11]
definitionBF
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content_tags.definitions[12]
key-termsbackward masking, forward masking, masker, tone, noise, signal, threshold, detection, dynamic range, suppression, firing, baseline, neurometric, window, ToneWin, TrialWin, psychophysical, perception, juvenile, adult, children, development, maturation, ACx, cortex, inferior colliculus, cochlear nucleus, inhibition, excitation, latency, population, cell, neuron, pooling, lower envelope, variability, anesthesia, urethane, awake, temporal, integration, speech, BF, multiunit, correlation, spontaneous
Concepts
terms this paper carries, each with the sentence it was cut from — the layer that joins one paper to another. Terms with no quote yet are on CONCEPTS.html.
conceptmasker — not defined in this paper's own words; the sound that follows
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concepts[2]
conceptthreshold — not defined in this paper's own words; the quantity compared with psychophysics
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concepts[6]
conceptdynamic range — not defined in this paper's own words; the second coding element, narrowed by the masker
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concepts[8]
conceptjuvenile — not defined in this paper's own words; the young animals
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concepts[18]
Statistics — cross-field join keys
field-invariant statistical terms, used in their statistical sense (gated on a number / symbol / test). A p-value or a standard deviation means the SAME thing in physics, biology, psychology and sociology — so these are the strongest cross-field join keys. Grounded verbatim.
Mann-Whitney U test z as written: Mann-Whitney U -tests for across-unit comparisons
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content_tags.statistics[0]
Wilcoxon signed-rank test z as written: The Wilcoxon signed-rank test
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content_tags.statistics[1]
Spearman rank correlation ρ as written: Spearman’s nonparametric rank correlation
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content_tags.statistics[2]
Fisher's exact test as written: Fisher’s exact tests of elevation differences
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content_tags.statistics[3]
ANCOVA (nonparametric ranked mixed model) F as written: nonparametric ranked mixed-model analysis of covariance (ANCOVA; Conover and Iman 1982 )
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content_tags.statistics[4]
bootstrap as written: repeated (bootstrapped) 1,000 times, drawing with replacement
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content_tags.statistics[5]
confidence interval 95% CI as written: 95% confidence intervals were calculated by bootstrapping
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content_tags.statistics[6]
principal component analysis PCA as written: sorted into single (SU) or multiunits (MU) on the basis of spike shape and principal component analysis
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content_tags.statistics[7]
standard error SE as written: variances are reported as SE
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content_tags.statistics[8]
percentiles / box plot summary as written: box edges are 25th and 75th percentiles
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content_tags.statistics[9]
evidence status notepercentiles / box plot summary — This quote ends with the stray word 'To', the first word of the next sentence. It is not trimmed, because the quote without it occurs more than once in the paper's text and could not be tied to one place. The claim is carried by the sentence before 'To'.content_tags.statistics[9]
principal component analysis
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.statistics[10]
correlation
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.statistics[11]
Second readings
a facet read a second time, independently, from its own sentence — and whether the two readings agree
claim typemechanism — a second reading reaching the same value; recorded: mechanism
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
alternatives.claim_type
methodneurometric thresholds computed in two analysis windows - one containing only the tone response, one containing the masker response as well — a second reading DIFFERING from the recorded value; recorded: electrophysiology
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
alternatives.method
phenomenonbackward masking - a higher threshold for a short tone when a masker follows it than for the same tone in silence — a second reading DIFFERING from the recorded value; recorded: auditory backward masking
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
alternatives.phenomenon

When we have changed our mind. Some entries in the table begin with a word in capitals and the reason for it. EVIDENCE CORRECTED — the finding still stands, but we had quoted the wrong sentence from the paper, and the quotation has been replaced with the right one. RETRACTED — the entry itself was wrong; it stays on the page, marked, with the reason, rather than being deleted. WITHDRAWN AND REPLACED — the entry was wrong, and a corrected version of it appears in the entries below. Each mark carries its own reason, in brackets, because the reasons differ from one entry to the next. An entry we have WITHDRAWN is removed from this page and kept in the record, with its reason. A line reading Audit and a date is a later re-reading of the entry against its whole sentence: DOUBTFUL means it was kept, and the reason says what is loose about it. Quotation marks inside the tagger's sentence. Where a tag is the tagger's own sentence, a phrase in quotation marks inside it is borrowed from the paper — the tagger's wording around it is not. The paper's own sentence is the evidence quote for that row; on this page it is withheld with the article, and the article is at its publisher. Nothing inside quotation marks anywhere on this page is ours: if it is quoted, it is the paper's. Whose words a concept carries. A concept entry records a term the paper itself uses, so the term, the sense given for it, and its evidence are the paper's own words, quoted where the paper fixes them. This is the opposite of a sense entry in the tag table, which is the tagger's sentence about how the paper uses a term. Where a concept entry could not be grounded in the paper's words, the entry says so on its own row.

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