Neurofunctional topography of the human hippocampus

Robinson, Barron, Kirby, Bottenhorn, Hill, Murphy, Katz, Salibi · Human Brain Mapping · 2015 · neuroscience · 10.1002/hbm.22987 · record Robinson2015-neurofunctional-topography-of-the-human-hipp
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Where this record's text came from. faceted 2026-08 by reading the locally held text (html); every evidence string verified as an exact substring of that text before merging. The supplied text begins with PMC site boilerplate and the full author/affiliation block; all quotes above are taken from the Abstract, Introduction, Methods, Results or Discussion, never from that header. The source uses U+2010 hyphens ('long‐axis', 'meta‐analytic', 'coactivation‐based') and these are preserved exactly. method is recorded as 'meta-analysis' because coactivation-based parcellation over BrainMap drives the parcellation, but the paper is genuinely multimodal - 7 T resting-state fMRI (n=23) and DTI (n=31) validate the clusters - and one method value cannot express that. The paper's partial DISagreement with the HERNET model ('we find less support for the notion that the anterior hippocampus recruits the dorsal attention network') was not recorded as a 'contradicts' relation because that sentence does not itself name the model or its author; the two 'extends' relations to Moser and Moser and to Kim cover the qualified-agreement stance. Replication status is 'untested' because the paper presents this as the first such model, notwithstanding its stated concordance with prior theories. 2026-08-13 schema-0.3 pass: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
This record’s own method is meta-analysis, and the tags below follow from that. A review’s findings, quantities and statistics are things stated IN this paper, and some of them report results obtained elsewhere. No tag on this page names a different author. Measured across every review in this corpus, 81% of a review’s tags carry no citation at all — most of them are the review speaking. The corpus does not adjudicate the rest: read an unmarked tag as a claim this paper makes, not necessarily one it made first.
How to read this page. The article itself is not reproduced here — this paper is not cleared for redistribution, so what follows is the tag layer alone. The evidence sentences are withheld with the article. The table at the foot lists every tag the record carries; each row names the facet it belongs to, and the whose words column says whether the tag records the paper's own wording or the tagger's sentence about the paper. Every tag links to each other paper in the corpus carrying it. The machine-readable edition of the same thing is the TEI file beside this one, where the tags live in standOff, and the article is at its publisher via the link below. When we have changed our mind. Some entries in the table begin with a word in capitals and the reason for it. EVIDENCE CORRECTED — the finding still stands, but we had quoted the wrong sentence from the paper, and the quotation has been replaced with the right one. RETRACTED — the entry itself was wrong; it stays on the page, marked, with the reason, rather than being deleted. WITHDRAWN AND REPLACED — the entry was wrong, and a corrected version of it appears in the entries below. Each mark carries its own reason, in brackets, because the reasons differ from one entry to the next. An entry we have WITHDRAWN is removed from this page and kept in the record, with its reason. A line reading Audit and a date is a later re-reading of the entry against its whole sentence: DOUBTFUL means it was kept, and the reason says what is loose about it. Quotation marks inside the tagger's sentence. Where a tag is the tagger's own sentence, a phrase in quotation marks inside it is borrowed from the paper — the tagger's wording around it is not. The paper's own sentence is the evidence quote for that row; on this page it is withheld with the article, and the article is at its publisher. Nothing inside quotation marks anywhere on this page is ours: if it is quoted, it is the paper's. Whose words a concept carries. A concept entry records a term the paper itself uses, so the term, the sense given for it, and its evidence are the paper's own words, quoted where the paper fixes them. This is the opposite of a sense entry in the tag table, which is the tagger's sentence about how the paper uses a term. Where a concept entry could not be grounded in the paper's words, the entry says so on its own row.
Other fields define these differently the same word, defined another way in another discipline
memory 23 fields · meta-analysis 4 fields · clustering 3 fields · functional connectivity 2 fields

Tags on this paper

Every tag the record carries, each linking to every other paper in the corpus that carries it. A tag appears here whether or not its words occur in the article — the spans below are only the ones a sentence in this paper licenses. Of the 45 concept tags on this paper, none is grounded in a quoted sentence. All carry the tagger's gloss of what the term means in this paper, which is not something the article can license.
hippocampus topography segmentation gradient clusters clustering voxel ROI thresholded probability coactivation BrainMap experiments activation behavioral domain paradigm class taxonomic label forward inference reverse inference binomial test ALE CBP filters deviants cluster size resting state DTI seed masks target masks functional connectivity structural connectivity lateralization anterior posterior amygdala parahippocampal gyrus occipital precuneus emotional perceptual encoding memory case study H.M. subiculum each hippocampal segment inherits its functional repertoire from the set of regions it is structurally and functionally wired to, so a segment connected to limbic, prefrontal, temporal and parietal cortex can carry out a correspondingly diverse set of cognitive processes the parcellation inherits the composition of its input database, and because BrainMap over-represents cognition-based studies the right hippocampus is left without a clean cluster solution coactivation-based parcellation (CBP) meta-analytic connectivity mapping (MACM) number of experiments percentage of misclassified voxels anatomical connectivity using a binomial test chi-squared z-score converted the non‐parametric P ‐values to z ‐scores false discovery rate correction thresholded at FDR‐corrected P k-means clustering K ‐means clustering was then performed permutation / null-distribution test compared the ALE scores to a null‐distribution reflecting random spatial associations between experiments χ 2 FDR correction activation likelihood estimation z ‐scores meta-analysis

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second readingalternativesan independent re-reading of a facet, recorded whether or not it agrees
relation to other workclaim_relationshow this paper stands to another: agrees, contradicts, extends, qualifies
claim typeclaim_typethe shape of the claim: existence, mechanism, method, critique, prediction, null
concept edgeconcept_edgesan asserted relation between two concepts, with the sentence asserting it
content tagcontent_tagsa finding, definition, quantity, statistic or variable named in the paper
contributioncontributionwhat the paper claims to add
controlcontrolsan experiment run to eliminate a rival explanation
limitationlimitationswhat the paper says its evidence cannot support
mechanismmechanismshow the reported effect is said to come about
methodmethodhow the paper produced its evidence
object of studyobject_of_studywhat the paper is about — the thing it investigates
phenomenonphenomenonthe effect or regularity under study
research questionresearch_questionthe question the paper sets itself
sensesensesa distinct use of a term, quoted where the paper fixes it
transfertransfersa method or concept carried in from another field

The paper

The full text is not reproduced here. This article is not cleared for redistribution, so the page carries the tag layer only. Its evidence sentences are withheld; the grounding status remains with each tag, and the article itself is at https://doi.org/10.1002/hbm.22987. The reading view exists for the papers whose licence permits it.

Every tag on this page

alternatives 3 · claim_relations 9 · claim_type 1 · concept_edges 8 · content_tags 90 · contribution 1 · controls 1 · limitations 11 · mechanisms 6 · method 1 · object_of_study 1 · phenomenon 1 · research_question 1 · senses 10 · transfers 4

Relations on this page carry a quotation for the claim. Where a relation was separately evidenced — and so tested against the vocabulary for its type — the row says so; none of 8 relations here carry that mark. The rest are the tagger’s reading of the sentence quoted beside them.

facettagfieldconf.whose words
object_of_studyhow the human hippocampus divides into functionally distinct parts along its long axis, derived from what the published literature reports rather than from one paradigm
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object_of_studythe paper's words
research_questionwhether a comprehensive data-driven parcellation of the hippocampus can be recovered from the coactivation structure of the published record
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research_questionthe paper's words
contributiona three-cluster parcellation of the left hippocampus with emotional, cognitive and perceptual profiles, and an ambiguous right hippocampus for which both a five-cluster and a two-cluster solution are reported and analysed
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contributionthe paper's words
claim_typeexistence
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claim_typethe paper's words
phenomenonlong-axis functional topography of the hippocampus
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phenomenonthe paper's words
methodmeta-analysis
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also in: meta-analysis
methodthe paper's words
mechanismsmechanisms
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mechanisms[0]the tagger's words
mechanismsmechanisms
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mechanisms[1]the tagger's words
mechanismsthe anterior portion is proposed to handle limbic or hot processing and the posterior spatial navigation and learned associations, a division carried over from rodent dorsal and ventral axes
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mechanisms[2]1.0the tagger's words
mechanismsthe right hippocampus may be functionally heterogeneous, which is offered as the reason its cluster solution is less stable
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mechanisms[3]0.8the tagger's words
mechanismsor the right hippocampus may not be organised by behavioural or stimulus features at all, so that its topography is a gradient rather than a set of parts
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mechanisms[4]0.7the tagger's words
mechanismsposterior segments connect to the posterior cingulate, a default mode hub, which is read as support for an internal attention account
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mechanisms[5]0.7the tagger's words
limitationsThe right hippocampal parcellation is underdetermined and needs more data to settle between the 5- and 2-cluster solutions.
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what this limits: the right hippocampal segmentation specifically: THE NEED FOR ADDITIONAL DATA TO FULLY PARSE THE SEGMENTATION OF THE RIGHT HIPPOCAMPUS
limitations[0]the tagger's words
limitationsThe right-hemisphere behavioural associations did not survive FDR correction.
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what this limits: the right-hemisphere behavioural associations only: THESE FUNCTIONS DID NOT SURVIVE FDR CORRECTION, THUS THE RIGHT BEHAVIORAL SUBSTRATES ARE INTERPRETED WITH CAUTION
limitations[1]the tagger's words
limitationsThe parcellation inherits the BrainMap database's bias toward cognition-based studies.
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what this limits: the functional coverage of the parcellation: THE DATA ARE RELIANT ON THE BRAINMAP DATABASE, WHICH HEAVILY FAVORS COGNITION-BASED FUNCTIONAL NEUROIMAGING STUDIES
limitations[2]the tagger's words
limitationsThe 7 T sample is small and more subjects would strengthen the connectivity results.
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what this limits: the connectivity results: ADDITIONAL SUBJECTS MAY HELP TO STRENGTHEN OUR UNDERSTANDING OF THE CONNECTIVITY OF THE TOPOGRAPHICAL SEGMENTS
limitations[3]the tagger's words
limitationsThe method forces discrete clusters and cannot represent a gradient organisation.
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what this limits: any claim that the organisation is discrete: THERE IS A GRADIENT COMPONENT TO PROCESSING WITHIN THE HIPPOCAMPUS THAT OUR CURRENT METHOD CANNOT ACCOUNT FOR
limitations[4]the tagger's words
limitationssegmentation is defined in terms of distinct clusters, and a gradient component is called plausible and likely and beyond what the current method can account for
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what this limits: the same scope as limitations[4] - the segmentation is DEFINED IN TERMS OF DISTINCT CLUSTERS, and a gradient is called PLAUSIBLE, AND LIKELY
limitations[5]1.0the tagger's words
limitationsthe right hippocampal behavioural associations did not survive correction and are explicitly interpreted with caution
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duplicate of: limitations[1] · what this limits: the same scope as limitations[1] - the right behavioural substrates, uncorrected
limitations[6]1.0the tagger's words
limitationsthe database heavily favours cognition studies, which is representative of the field but may itself be why no obvious right hippocampal solution emerged
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what this limits: the same scope as limitations[2], with the paper's own defence: WHILE THIS IS REPRESENTATIVE OF THE FIELD AS A WHOLE, HAVING A MORE BALANCED database would change what can be found
limitations[7]1.0the tagger's words
limitationsuncovering the right hemisphere's ambiguous results is said to need increasing the number of papers in the BrainMap database, and submillimeter fMRI specifically targeting the hippocampus
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what this limits: the right hemisphere's ambiguous results, and the subiculum finding in particular: TWO AVENUES OF ADDITIONAL WORK ARE NECESSARY TO UNCOVER THE RIGHT HEMISPHERE'S AMBIGUOUS RESULTS, PARTICULARLY IN LIGHT OF THE SUBFIELD (I.E., SUBICULUM) FINDING
limitations[8]1.0the tagger's words
limitationswhich of the two right hippocampal solutions is correct is left open until the database grows
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what this limits: the choice between the two right-hippocampus solutions: WE PRESENTED BOTH A 5-CLUSTER AND A 2-CLUSTER SOLUTION, AS THE 5-CLUSTER SOLUTION WAS DEEMED TO BE MARGINALLY BETTER
limitations[9]1.0the tagger's words
limitationsthe imaging validation rests on 23 resting-state and 31 diffusion participants
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what this limits: the imaging validation: TWENTY-THREE HEALTHY INDIVIDUALS were scanned for resting state, with a separate diffusion sample
limitations[10]1.0the tagger's words
transfersactivation likelihood estimation against a null of random spatial association, used here to characterise each cluster rather than to test a hypothesis
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transfers[0]1.0the tagger's words
transfersbehavioral domain, paradigm class and subject population coded alongside the stereotactic coordinates of every archived study
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transfers[1]1.0the tagger's words
transfersclustering that separates the voxels in the ROI into k clusters by minimizing the variance within clusters and maximizing the variance between clusters
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transfers[2]1.0the tagger's words
transfersthe dorsal to ventral axis and its hot and cold processing division, mapped onto the human posterior to anterior axis
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transfers[3]1.0the tagger's words
controlsthe resting-state and DTI analyses run twice, with and without the left-handed participants
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eliminates: handedness driving a lateralised functional or structural result · outcome (stated by the tagger, no quotation): held
controls[0]0.85the tagger's words
sensesTHE NUMBER OF PARTS IS A CHOICE, AND THE CRITERIA DISAGREE: misclassified voxels favour 2 to 4 on the left and 2, 3 or 5 on the right; minimum-to-mean cluster size favours 2 and 3 for both; intercluster distance favours 3 on the left and 2 or 5 on the right
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senses[0]1.0the tagger's words
sensesand the reported answer is a combination of them - three parts on the left, five on the right - so how many objects the hippocampus contains is a product of how the criteria were weighed
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senses[1]1.0the tagger's words
sensesTWO PARCELLATIONS OF THE SAME STRUCTURE ARE CARRIED THROUGH THE WHOLE PAPER: the five-cluster right solution is called marginally better than the two-cluster one, and both get their own connectivity analyses
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senses[2]1.0the tagger's words
sensesTHE METHOD CAN ONLY RETURN PARTS: k-means assigns every voxel to one of k non-overlapping clusters, so a structure organised as a gradient would still come back as clusters
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senses[3]1.0the tagger's words
sensesand the paper says exactly that - segmentation into distinct clusters is a definitional choice, a gradient is plausible and likely, and the method cannot account for it
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senses[4]1.0the tagger's words
sensesTHE OBJECT IS DEFINED BY A THRESHOLD ON A PROBABILITY MAP: the region of interest is an atlas thresholded at 75 percent, chosen to be conservative and to be easy to describe to other researchers
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senses[5]1.0the tagger's words
sensesTHE SAME TAGS ARE READ IN BOTH DIRECTIONS: forward inference asks whether a label is more likely to activate this cluster than the database at large, reverse inference asks which label is most likely given activation here
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senses[6]1.0the tagger's words
sensesAND THE CORPUS'S SKEW BECOMES THE ANSWER'S SKEW: the database favours cognition studies, which the paper says is representative of the field, and offers that imbalance as a reason the right hippocampus yielded no clean solution
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senses[7]1.0the tagger's words
sensesTHE FOUNDATIONAL RECORD WAS WRONG: half a century of assumptions rest on one patient whose lesion, when finally imaged, did not match the surgical account of it
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senses[8]1.0the tagger's words
sensesa result that did not survive correction is reported anyway, labelled, and interpreted with caution rather than dropped
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senses[9]1.0the tagger's words
alternativesclaim_type: existence
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a second reading reaching the same value. Recorded: existence — note: a second reading reaching the same value from a different sentence. Not applied - a person decides.
alternatives.claim_typethe tagger's words
alternativesmethod: coactivation-based parcellation of every voxel in the hippocampal region of interest using the BrainMap database, k-means over the coactivation profiles, then activation likelihood estimation, forward and reverse functional decoding, resting-state connectivity and diffusion tractography
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a second reading DIFFERING from the recorded value. Recorded: meta-analysis — note: a second reading, verbatim-verified, disagreeing with the value on the record. Not applied - a person decides.
alternatives.methodthe tagger's words
alternativesphenomenon: a functional gradient along the long axis of the hippocampus, with limbic processing anteriorly and perceptual or spatial processing posteriorly
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a second reading DIFFERING from the recorded value. Recorded: long-axis functional topography of the hippocampus — note: a second reading, verbatim-verified, disagreeing with the value on the record. Not applied - a person decides.
alternatives.phenomenonthe tagger's words
claim_relationsreplicates → Fanselow and Dong (2010); King et al. (2008)
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claim_relations[0]the tagger's words
claim_relationsextends → Moser and Moser (1998) model and the HERNET model
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claim_relations[1]the tagger's words
claim_relationsextends → Kim (2015) HERNET model
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claim_relations[2]the tagger's words
claim_relationsextends → Moser and Moser's dorsal to ventral hippocampal gradient, imported from rodent connectivity and behaviour
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claim_relations[3]1.0the tagger's words
claim_relationsqualifies → that same model, by finding hot and cold processing along the axis but also cold processing anteriorly on the right
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claim_relations[4]1.0the tagger's words
claim_relationsqualifies → Kim's hippocampal encoding and retrieval network model, supporting its posterior default mode claim and not its anterior dorsal attention claim
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claim_relations[5]1.0the tagger's words
claim_relationscritiques → the single-paradigm designs that dominate the field, which cannot say whether other neurocognitive processes use the same subregions
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differs in: THE AXIS IS THE NUMBER OF TASKS PER STUDY. 'these results support the fundamental argument that the hippocampus maintains a neurofunctional topographical organization, but Quotation withheld [task].' The topography is granted and the specificity is not - and no accumulation of single-task studies can supply it, so the missing result is not a matter of more evidence.
claim_relations[6]1.0the tagger's words
claim_relationscritiques → the inferential base of the field itself - non-human data, case studies, and narrowly focused cognitive experiments
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claim_relations[7]1.0the tagger's words
claim_relationssupports → Chase and colleagues' five-cluster parcellation of the subiculum by nearly identical methodology
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claim_relations[8]1.0the tagger's words
concept_edgesclusters —distinct-from→ gradient
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strength of the relation: 1 · note: THE OUTPUT TYPE IS A PROPERTY OF THE METHOD: defining the topography as distinct clusters is called a theoretical choice, and a gradient is called plausible and likely and beyond what the method can represent Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but a gradient component is 'plausible, and likely' beside the clusters; distinct-from is loose.
also in: clusters · gradient
concept_edges[0]1.0the tagger's words
concept_edgesbehavioral domain —distinct-from→ paradigm class
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strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the two are listed as separate metadata fields; distinct-from is loose.
concept_edges[11]1.0the tagger's words
concept_edgesforward inference —operationalised-as→ taxonomic label
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strength of the relation: 1 · note: THE SAME TAG READ IN ONE DIRECTION: is activation more probable for this label inside the cluster than across the whole database Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the forward-inference profile is computed from activation probabilities per taxonomic label; operationalised-as is loose.
concept_edges[13]1.0the tagger's words
concept_edgesforward inference —operationalised-as→ binomial test
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strength of the relation: 1 Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but a binomial test was USED WITHIN the forward-inference approach to judge significance; operationalised-as is loose.
concept_edges[14]1.0the tagger's words
concept_edgesreverse inference —operationalised-as→ behavioral domain
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strength of the relation: 1 · note: AND IN THE OTHER: which label is most likely given activation here - the two questions are not the same and both are reported Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the reverse-inference profile identifies the most likely behavioral domain; operationalised-as is loose.
concept_edges[15]1.0the tagger's words
concept_edgesseed masks —distinct-from→ target masks
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strength of the relation: 1 · note: each cluster against 110 atlas regions, themselves thresholded at 50 percent - a second layer of cuts underneath the first
concept_edges[19]1.0the tagger's words
concept_edgesanterior —contrasted-with→ posterior
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strength of the relation: 1 · note: the hot and cold division, carried across from the rodent ventral and dorsal poles Audit 2026-09-28: DOUBTFUL - read against its full span and kept, but the contrast is what earlier authors 'speculated' about ventral and dorsal portions; attributed and hedged.
also in: anterior · posterior
concept_edges[26]1.0the tagger's words
concept_edgesH.M. —is-a→ case study
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strength of the relation: 1 · note: THE FOUNDATIONAL RECORD WAS WRONG: imaging in the 1990s revealed discrepancies in the neurosurgical account of the lesion, confirmed after death
also in: H.M. · case study
concept_edges[32]1.0the tagger's words
content_tagsbinomial test
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also in: binomial test
content_tags.statistics[0]the tagger's words
content_tagschi-squared
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also in: chi-squared
content_tags.statistics[1]the tagger's words
content_tagsz-score
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also in: z-score
content_tags.statistics[2]the tagger's words
content_tagsfalse discovery rate correction
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content_tags.statistics[3]the tagger's words
content_tagsk-means clustering
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content_tags.statistics[4]the tagger's words
content_tagspermutation / null-distribution test
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content_tags.statistics[5]the tagger's words
content_tagsbinomial test
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also in: binomial test
content_tags.statistics[6]1.0the tagger's words
content_tagsχ 2
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also in: χ 2
content_tags.statistics[7]1.0the tagger's words
content_tagsFDR correction
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content_tags.statistics[8]1.0the tagger's words
content_tagsactivation likelihood estimation
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content_tags.statistics[9]1.0the tagger's words
content_tagsz ‐scores
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also in: z ‐scores
content_tags.statistics[10]1.0the tagger's words
content_tagsThe left hippocampus divides into three anterior-to-posterior clusters: an emotional cluster tied to amygdala and parahippocampal gyrus, a cognitive cluster tied to anterior cingulate and inferior frontal gyrus, and a posterior perceptual cluster tied to occipital lobe, precuneus and angular gyrus.
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content_tags.findings[0]the tagger's words
content_tagsThe right hippocampus does not yield one clear parcellation: both a 2-cluster and a 5-cluster solution remain plausible.
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content_tags.findings[1]the tagger's words
content_tagsThe anterior-most left cluster was behaviourally characterised by face monitoring/discrimination, cued explicit recall and encoding.
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content_tags.findings[2]the tagger's words
content_tagsThe middle left cluster was characterised by paired associate recall, cued explicit recognition and encoding.
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content_tags.findings[3]the tagger's words
content_tagsThe behavioural labels attached to the right-hippocampal clusters failed FDR correction, so they are reported only with caution.
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content_tags.findings[4]the tagger's words
content_tagsDiffusion tractography showed the posterior left cluster connecting to the occipital lobe, specifically lingual gyrus and occipital pole, alongside parahippocampal, posterior cingulate and amygdala connections.
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content_tags.findings[5]the tagger's words
content_tagsInterhemispheric structural connections increase toward the posterior end of both left and right hippocampus.
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content_tags.findings[6]the tagger's words
content_tagsLeft and right hippocampus produce different clustering profiles, which the authors read as evidence of hemispheric lateralization.
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content_tags.findings[7]the tagger's words
content_tagsThe data support a hot-to-cold anterior-posterior gradient but depart from it in one respect: anterior right-hemisphere portions are also engaged in "cold" processing.
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content_tags.findings[8]the tagger's words
content_tagsthe left hippocampus divided into three segments running anterior to posterior, associated with faces and recall, with paired associate recall and recognition, and with perception
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content_tags.findings[9]1.0the tagger's words
content_tagsthe right hippocampus divided into five regions, less well defined behaviourally than the left
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content_tags.findings[10]1.0the tagger's words
content_tagsAND THOSE RIGHT-SIDE LABELS DID NOT SURVIVE CORRECTION, which the paper states and then interprets with caution rather than dropping them
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content_tags.findings[11]1.0the tagger's words
content_tagsan alternative to the 5‐cluster model is a 2‐cluster solution, found to be slightly less favorable, with an anterior and a posterior segment
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content_tags.findings[12]1.0the tagger's words
content_tagsBOTH SOLUTIONS ARE PRESENTED: the 5‐cluster solution was deemed marginally better than the 2‐cluster solution, and which is ideal may become clearer as more data is added to the database
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content_tags.findings[13]1.0the tagger's words
content_tagsTHE CRITERIA FOR HOW MANY CLUSTERS DISAGREE WITH EACH OTHER: deviant percentage, minimum-to-mean cluster size and intercluster distance each favour a different set of solutions
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content_tags.findings[14]1.0the tagger's words
content_tagsand the reported answer is their combination - three on the left, five on the right
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content_tags.findings[15]1.0the tagger's words
content_tagsthe criteria are stated as rules in advance: the percentage of deviants not significantly increased compared with the k − 1 solution, the minimum cluster size more than half of the average cluster size, and no significantly larger increase in intercluster to intracluster distance
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content_tags.findings[16]1.0the tagger's words
content_tagsclustering separates the voxels in the ROI into k non‐overlapping clusters, minimizing the variance within clusters and maximizing the variance between clusters, with centroids chosen at random for each new iteration
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content_tags.findings[17]1.0the tagger's words
content_tagsk values from 2 to 7 were computed for each region before any selection
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content_tags.findings[18]1.0the tagger's words
content_tagsTHE METHOD CANNOT REPRESENT A GRADIENT, and the paper says a gradient is plausible and likely
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content_tags.findings[19]1.0the tagger's words
content_tagsand offers the same ambiguity a second reading - the right hippocampus may simply not be organised by behavioural or stimulus features
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content_tags.findings[20]1.0the tagger's words
content_tagsthe region of interest is an atlas thresholded at 75 percent, described as conservative and as easy to communicate
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content_tags.findings[21]1.0the tagger's words
content_tagswith mean membership probability of 86 to 88 percent and centroids above 97 percent
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content_tags.findings[22]1.0the tagger's words
content_tagsthe database holds 2,630 papers, 12,623 experiments, 100 paradigm classes and 52,289 subjects
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content_tags.findings[23]1.0the tagger's words
content_tagsand stores each paper as significant coordinates plus coded metadata - behavioral domain, paradigm class and subject population
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content_tags.findings[24]1.0the tagger's words
content_tagsonly healthy normal-mapping experiments were used, with no restriction by domain or paradigm, to keep the model unconstrained
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content_tags.findings[25]1.0the tagger's words
content_tagsNO SINGLE VOXEL HAS ENOUGH STUDIES, so each borrows the nearest reported activations by Euclidian distance and its profile is a neighbourhood rather than a measurement
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content_tags.findings[26]1.0the tagger's words
content_tagsthe number of nearest experiments was swept from 20 to 200 in steps of 5, and stable ranges chosen by fewest deviant voxels
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content_tags.findings[27]1.0the tagger's words
content_tagsFORWARD INFERENCE asks whether a label is more likely to activate inside the cluster than across the database, tested binomially
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content_tags.findings[28]1.0the tagger's words
content_tagsREVERSE INFERENCE asks which label is most likely given activation in the cluster, tested by chi square
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content_tags.findings[29]1.0the tagger's words
content_tagscluster profiles were built by activation likelihood estimation against a null of random spatial association, corrected family-wise
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content_tags.findings[30]1.0the tagger's words
content_tagsTHE DATABASE'S SKEW IS OFFERED AS AN EXPLANATION OF THE RESULT: it heavily favours cognition studies, which is representative of the field, and may be why no obvious right hippocampal solution emerged
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content_tags.findings[31]1.0the tagger's words
content_tagsand the two avenues named are increasing the number of papers in the BrainMap database, and submillimeter fMRI specifically targeting the hippocampus
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content_tags.findings[32]1.0the tagger's words
content_tagsTHE FIELD'S FOUNDATIONAL RECORD WAS WRONG: imaging decades later revealed discrepancies in the surgical account of H.M.'s lesion, confirmed after his death
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content_tags.findings[33]1.0the tagger's words
content_tagsand the field's inferences are said to rest on non-human data, case studies, and single-process experiments
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content_tags.findings[34]1.0the tagger's words
content_tagsprior parcellation work used one paradigm at a time, so it could not say whether other processes use the same subregions
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content_tags.findings[35]1.0the tagger's words
content_tagsleft anterior clusters connected structurally to the amygdala, thalamus and parahippocampal gyrus, with brainstem connections in most of the sample
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content_tags.findings[36]1.0the tagger's words
content_tagsthe posterior left cluster reached the lingual gyrus and occipital pole and lacked the sub-lobar connections of the others
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content_tags.findings[37]1.0the tagger's words
content_tagsthe fourth right cluster had the most diverse connectivity of all, which is used to argue for adding studies rather than for a functional claim
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content_tags.findings[38]1.0the tagger's words
content_tagsinterhemispheric connections increased toward the posterior end on both sides
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content_tags.findings[39]1.0the tagger's words
content_tagstracts were kept only where present in more than 15 percent of the sample with connection probability above 10 percent
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content_tags.findings[40]1.0the tagger's words
content_tagseach cluster was scored against 110 atlas target masks thresholded at 50 percent
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content_tags.findings[41]1.0the tagger's words
content_tagsanatomical labels come from the Talairach Demon applied to the coordinates
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about this quote: This quote ends with the stray word 'For', the first word of the next sentence. It is not trimmed, because the quote without it occurs more than once in the paper's text and could not be tied to one place. The claim is carried by the sentence before 'For'.
content_tags.findings[42]0.85the tagger's words
content_tagstwenty-three healthy individuals were scanned with a resting-state EPI sequence optimised for the hippocampus
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content_tags.findings[43]1.0the tagger's words
content_tagspartial concordance with the hot and cold model: the axis holds, but anterior right clusters also carry cold processes
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content_tags.findings[44]1.0the tagger's words
content_tagsposterior clusters connect to the posterior cingulate, supporting the default mode half of the encoding-retrieval model and not its anterior half
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content_tags.findings[45]1.0the tagger's words
content_tagsa companion study parcellating only the subiculum with nearly identical methods also found five clusters
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content_tags.findings[46]1.0the tagger's words
content_tagsvery few studies address lateralization in this literature, though most have theorized that the right hippocampus is engaged in spatial processing and the left attuned to verbal information
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content_tags.findings[47]1.0the tagger's words
content_tagscoactivation-based parcellation (CBP)
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content_tags.definitions[0]the tagger's words
content_tagsmeta-analytic connectivity mapping (MACM)
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.definitions[2]the tagger's words
content_tagsforward inference
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.definitions[3]the tagger's words
content_tagsreverse inference
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.definitions[4]the tagger's words
content_tagsclustering
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
also in: clustering
content_tags.definitions[7]1.0the tagger's words
content_tagsBrainMap
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also in: BrainMap
content_tags.definitions[8]1.0the tagger's words
content_tagsforward inference
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.definitions[9]1.0the tagger's words
content_tagsreverse inference
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.definitions[10]1.0the tagger's words
content_tagsALE
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also in: ALE
content_tags.definitions[11]1.0the tagger's words
content_tagsdeviants
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
also in: deviants
content_tags.definitions[12]1.0the tagger's words
content_tagsnumber of experiments
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content_tags.variables[1]the tagger's words
content_tagspercentage of misclassified voxels
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.variables[2]the tagger's words
content_tagsanatomical connectivity
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.variables[4]the tagger's words
content_tagsdeviants
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
also in: deviants
content_tags.variables[7]1.0the tagger's words
content_tagscluster size
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
also in: cluster size
content_tags.variables[8]1.0the tagger's words
content_tagsprobability
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
also in: probability
content_tags.variables[9]1.0the tagger's words
content_tagsfunctional connectivity
Quotation withheld — this record is not cleared for redistribution. The sentence is in the paper at the link above.
content_tags.variables[10]1.0the tagger's words
content_tagsstructural connectivity
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content_tags.variables[11]1.0the tagger's words
content_tags2,630 papers, 12,623 experiments, 100 paradigm classes, 52,289 subjects — size of the BrainMap database at the time of the analysis
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content_tags.quantities[0]the tagger's words
content_tags1,880 mm 3 / 2,072 mm 3 — volumes of the left and right hippocampal regions of interest
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content_tags.quantities[1]the tagger's words
content_tagsTwenty-three — number of healthy participants scanned for the 7T resting-state fMRI
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content_tags.quantities[2]the tagger's words
content_tags31 — number of healthy participants scanned for the diffusion tensor imaging
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content_tags.quantities[3]the tagger's words
content_tags1,000 iterations — number of K-means restarts used to search for the optimal clustering solution
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content_tags.quantities[4]the tagger's words
content_tags15% / 10% — tractography thresholds: paths present in more than 15% of the sample and tracts with connection probability above 10%
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content_tags.quantities[5]the tagger's words
content_tags75% — the atlas probability at which the hippocampal region of interest was cut out, which is what fixes the object's boundary
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content_tags.quantities[6]1.0the tagger's words
content_tags2,630 papers — the database behind every data point here: 12,623 experiments, 100 paradigm classes and 52,289 subjects
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content_tags.quantities[7]1.0the tagger's words
content_tags20 through 200 — nearest experiments per voxel, swept in steps of 5, with the stable range chosen by fewest deviant voxels
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content_tags.quantities[8]1.0the tagger's words
content_tags2 through 7 — the cluster counts computed for each region before any criterion was applied
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content_tags.quantities[9]1.0the tagger's words
content_tags3, and for the right, 5 — the cluster counts finally reported, arrived at by combining criteria that individually favoured different numbers
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content_tags.quantities[10]1.0the tagger's words
content_tags15% — the share of the sample in which a tract had to be present to be kept, alongside a 10 percent connection probability
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content_tags.quantities[11]1.0the tagger's words
content_tags110 total masks — atlas targets, themselves thresholded at 50 percent, that the tractography is sorted into
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content_tags.quantities[12]1.0the tagger's words

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