Coding of auditory temporal and pitch information by hippocampal individual cells and cell assemblies in the rat

Sakurai · Neuroscience · 2002 · neuroscience · 10.1016/s0306-4522(02)00509-2 · record Sakurai2002-coding-of-auditory-temporal-and-pitch-inform
tag layer · index · concepts · authors · עברית
Where this record's text came from. faceted 2026-08 by reading the locally held text (pdftext); every evidence string verified as an exact substring of that text before merging. The source is pdftext with ligature corruption (¡ = ff, ¢ = fi, £ = fl, W = micro), so several verbatim quotes carry mangled characters - they are reproduced exactly as they appear in the file. Claim type is 'mechanism' because the headline claim is an account of how coding is divided between levels; a secondary, negative claim ('temporal information ... cannot be coded independently by speci¢c neurons') is close to a null-result and is not captured by the single claim type field. The Bergson relation is philosophical rather than empirical: the paper says its data 'support' Bergson's 1889 theory, recorded here as builds-on for lack of a closer relation type. 2026-08-14 and 2026-08-25 schema-0.3 passes: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
Some words in these quotes contain the wrong character. The PDF this text was extracted from substituted 23 characters inside a word — a currency sign or a stray accent where a letter pair belongs, as in signi¢cantly for significantly, or a single ligature glyph, as in confidence. They are valid characters in the wrong place, so they survive every encoding check. The quotes keep them for the same reason as above, and a search of this page will not find the affected words.
How to read this page. The article itself is not reproduced here — this paper is not cleared for redistribution, so what follows is the tag layer alone. The evidence sentences are withheld with the article. The table at the foot lists every tag the record carries; each row names the facet it belongs to, and the whose words column says whether the tag records the paper's own wording or the tagger's sentence about the paper. Every tag links to each other paper in the corpus carrying it. The machine-readable edition of the same thing is the TEI file beside this one, where the tags live in standOff, and the article is at its publisher via the link below. When we have changed our mind. Some entries in the table begin with a word in capitals and the reason for it. EVIDENCE CORRECTED — the finding still stands, but we had quoted the wrong sentence from the paper, and the quotation has been replaced with the right one. RETRACTED — the entry itself was wrong; it stays on the page, marked, with the reason, rather than being deleted. WITHDRAWN AND REPLACED — the entry was wrong, and a corrected version of it appears in the entries below. Each mark carries its own reason, in brackets, because the reasons differ from one entry to the next. An entry we have WITHDRAWN is removed from this page and kept in the record, with its reason. A line reading Audit and a date is a later re-reading of the entry against its whole sentence: DOUBTFUL means it was kept, and the reason says what is loose about it. Quotation marks inside the tagger's sentence. Where a tag is the tagger's own sentence, a phrase in quotation marks inside it is borrowed from the paper — the tagger's wording around it is not. The paper's own sentence is the evidence quote for that row; on this page it is withheld with the article, and the article is at its publisher. Nothing inside quotation marks anywhere on this page is ours: if it is quoted, it is the paper's. Whose words a concept carries. A concept entry records a term the paper itself uses, so the term, the sense given for it, and its evidence are the paper's own words, quoted where the paper fixes them. This is the opposite of a sense entry in the tag table, which is the tagger's sentence about how the paper uses a term. Where a concept entry could not be grounded in the paper's words, the entry says so on its own row.
Other fields define these differently the same word, defined another way in another discipline
confidence interval 2 fields

Tags on this paper

Every tag the record carries, each linking to every other paper in the corpus that carries it. A tag appears here whether or not its words occur in the article — the spans below are only the ones a sentence in this paper licenses. Of the 5 concept tags on this paper, all 5 are grounded in a quoted sentence.
cell assemblies single neurons dual coding Cross-correlation analysis philosophical argument Individual neurons belong to more than one cell assembly, so an assembly can distinguish two tasks that no single member neuron can distinguish - which is how the rat behaves differently while single-cell activity does not differentiate Coding a task consists in the neurons of the corresponding assembly becoming correlated in activity while that task is being performed single-neuron coding cell-assembly coding type of information discriminative stimulus activity correlation Wilcoxon signed-rank test Kruskal-Wallis test Kruskal^Wallis H Mann-Whitney U test Mann^Whitney U tests chi-squared confidence interval electrophysiology

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relation to other workclaim_relationshow this paper stands to another: agrees, contradicts, extends, qualifies
claim typeclaim_typethe shape of the claim: existence, mechanism, method, critique, prediction, null
concept edgeconcept_edgesan asserted relation between two concepts, with the sentence asserting it
conceptconceptsan idea the paper works with, quoted where the paper uses it
content tagcontent_tagsa finding, definition, quantity, statistic or variable named in the paper
controlcontrolsan experiment run to eliminate a rival explanation
limitationlimitationswhat the paper says its evidence cannot support
mechanismmechanismshow the reported effect is said to come about
methodmethodhow the paper produced its evidence
phenomenonphenomenonthe effect or regularity under study
sensesensesa distinct use of a term, quoted where the paper fixes it
transfertransfersa method or concept carried in from another field

The paper

The full text is not reproduced here. This article is not cleared for redistribution, so the page carries the tag layer only. Its evidence sentences are withheld; the grounding status remains with each tag, and the article itself is at https://doi.org/10.1016/s0306-4522(02)00509-2. The reading view exists for the papers whose licence permits it.

Every tag on this page

claim_relations 3 · claim_type 1 · concept_edges 1 · concepts 5 · content_tags 25 · controls 1 · limitations 6 · mechanisms 2 · method 1 · phenomenon 1 · senses 3 · transfers 1

Relations on this page carry a quotation for the claim. Where a relation was separately evidenced — and so tested against the vocabulary for its type — the row says so; none of 1 relation here carry that mark. The rest are the tagger’s reading of the sentence quoted beside them.

facettagfieldconf.whose words
claim_typemechanism
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claim_typethe paper's words
phenomenonhippocampal cell-assembly coding of auditory pitch and duration
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phenomenonthe paper's words
methodelectrophysiology
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methodthe paper's words
mechanismsmechanisms
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mechanisms[0]the tagger's words
mechanismsmechanisms
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mechanisms[1]the tagger's words
limitationsThe pitch and duration information may in fact be coded first in sensory cortex and only reflected in hippocampus.
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what this limits: the claim that the hippocampus codes this information: THE SENSORY INFORMATION OF INPUTS (DURATION AND PITCH) AND/OR THE TASKS WITH THEM MIGHT BE CODED AND PROCESSED FIRST IN SENSORY AREAS AND THEN PASSED ONTO AND REFLECTED IN THE HIPPOCAMPAL FORMATION
limitations[0]the tagger's words
limitationsRecording within one region cannot capture assemblies that are distributed across regions.
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what this limits: the assemblies this design can detect: INVESTIGATION OF A GLOBAL CELL ASSEMBLY AMONG PLURAL REGIONS IS NECESSARY, BECAUSE ENSEMBLE CODING BY CELL ASSEMBLIES CAN BE DIFFUSE
limitations[1]the tagger's words
limitationsWhether the dual-coding scheme generalises beyond hippocampus is untested here.
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what this limits: the generality of the dual-coding scheme: OTHER BRAIN REGIONS SHOULD ALSO BE STUDIED, AS DUAL CODING WITH CELL ASSEMBLY MIGHT BE COMMON ACROSS MANY DIFFERENT BRAIN REGIONS
limitations[2]the tagger's words
limitationsNeuron pairs with fewer than 2000 combined discharges were excluded from the cross-correlation analysis.
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what this limits: every cross-correlation result, which describes the more active pairs: NEURON PAIRS WHOSE COMBINED TOTAL NUMBERS OF DISCHARGES WERE LESS THAN 2000 DURING A TASK WERE NOT INCLUDED
limitations[3]the tagger's words
limitationsThe cell-assembly model is described as supported by the correlation analysis, not established by it.
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what this limits: the cell-assembly account offered here: the authors state that cross-correlation analysis among simultaneously recorded neurons supported the suggested model
limitations[4]1.0the tagger's words
limitationsThe interpretation of temporal coding rests on an imported philosophical argument.
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what this limits: the claim that time is coded together with other stimulus attributes: the authors invoke a philosophical argument that we tend to perceive time not as independent information but as information concomitant with other physical attributes of stimuli
limitations[5]1.0the tagger's words
transfersBergson's philosophical account of time perception is imported as the interpretive model for why duration is never coded on its own but always alongside another stimulus attribute
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transfers[0]the tagger's words
controlsone of the four discriminative stimuli presented in random order at the start of every trial, in both tasks
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eliminates: the animal anticipating which stimulus is coming - a predictable sequence would let it prepare the response before the stimulus arrives, which is the thing the neurons are being read for · outcome (stated by the tagger, no quotation): held
controls[0]0.85the tagger's words
conceptscell assemblies
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concepts[0]the paper's words
conceptssingle neurons
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concepts[1]the paper's words
conceptsdual coding
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also in: dual coding
concepts[2]the paper's words
conceptsCross-correlation analysis
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concepts[3]the paper's words
conceptsphilosophical argument
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concepts[4]the paper's words
sensesthe division of labour - TWO LEVELS, TWO OBJECTS, IN ONE SENTENCE: single neurons encode the auditory pitches and temporal lengths themselves, while cell assemblies encode the TYPE OF TASK - the context in which that information is processed - so 'the hippocampus codes pitch' is true at one level and beside the point at the other
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senses[0]1.0the tagger's words
sensesdual coding - A BORROWED NAME, ATTRIBUTED: the paper states the phenomenon HAS BEEN CALLED dual coding and cites the source, then reports it demonstrated in several brain regions, so the term arrives with a history rather than being coined here; the citation itself is cut from the span because the staged text mangles the author name
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senses[1]1.0the tagger's words
sensesthe cell-assembly model's standing - SUPPORTED BY A CORRELATION: the verification is that cross-correlation analysis among simultaneously recorded neurons supported the suggested model, which is a consistency check rather than an independent measurement of an assembly
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senses[2]1.0the tagger's words
claim_relationsextends → Sakurai (1996a) cell-assembly coding model of stimulus-discrimination tasks
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claim_relations[0]the tagger's words
claim_relationsbuilds-on → dual-coding hypothesis (Arieli et al., 1996; Riehle et al., 1997; de Oliveira et al., 1997)
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claim_relations[1]the tagger's words
claim_relationsbuilds-on → Henri Bergson's theory of the perception of time (Bergson, 1889)
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claim_relations[2]the tagger's words
concept_edgescell assemblies —contrasted-with→ single neurons
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differs in: what each level encodes: the stimulus attributes themselves, or the type of task in which they are processed · strength of the relation: 1
concept_edges[0]the tagger's words
content_tagsWilcoxon signed-rank test
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content_tags.statistics[0]the tagger's words
content_tagsKruskal-Wallis test
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content_tags.statistics[1]the tagger's words
content_tagsMann-Whitney U test
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content_tags.statistics[2]the tagger's words
content_tagschi-squared
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also in: chi-squared
content_tags.statistics[3]the tagger's words
content_tagsconfidence interval
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content_tags.statistics[4]the tagger's words
content_tagsEvery hippocampal neuron that discriminated long from short tones in the duration task was also task-related in the pitch task, without exception.
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content_tags.findings[0]the tagger's words
content_tagsNeurons related only to the pitch task were the most numerous class, and not a single neuron was related to the duration task alone.
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content_tags.findings[1]the tagger's words
content_tagsThe author infers that temporal information cannot be coded independently by dedicated neurons, whereas pitch information can.
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content_tags.findings[2]the tagger's words
content_tagsThe cell assembly encoding the duration task is not separate but sits entirely inside the assembly encoding the pitch task.
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content_tags.findings[3]the tagger's words
content_tags37 neuron pairs supported the nested cell-assembly hypothesis against 11 that did not.
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content_tags.findings[4]the tagger's words
content_tagsThe study concludes for dual coding: single neurons carry both the pitch and the duration of the tones, while cell assemblies carry which task (context) the animal is performing.
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content_tags.findings[5]the tagger's words
content_tagsdual coding
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also in: dual coding
content_tags.definitions[0]the tagger's words
content_tagscross-correlation analysis
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content_tags.definitions[2]the tagger's words
content_tagssingle-neuron coding
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content_tags.definitions[4]the tagger's words
content_tagscell-assembly coding
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content_tags.definitions[5]the tagger's words
content_tagstype of information
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content_tags.variables[0]the tagger's words
content_tagsdiscriminative stimulus
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content_tags.variables[1]the tagger's words
content_tagsactivity correlation
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content_tags.variables[2]the tagger's words
content_tags113 — total hippocampal neurons recorded, split 68 in CA1 and 45 in CA3
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content_tags.quantities[0]the tagger's words
content_tags48 — neuron pairs that entered the cross-correlation analysis, 28 from CA1 and 20 from CA3
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content_tags.quantities[1]the tagger's words
content_tags37 ... 11 — neuron pairs supporting versus contradicting the nested cell-assembly model
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content_tags.quantities[2]the tagger's words
content_tagsX2(2) = 48.1, P 6 .001 — chi-squared test showing the three classes of task-related neurons differ in proportion
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content_tags.quantities[3]the tagger's words
content_tags12 — number of 5-month-old male albino rats used
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content_tags.quantities[4]the tagger's words
content_tags85 dB ... 10 kHz ... 2 kHz — intensity and the high/low frequencies of the four discriminative tones, presented at 3 s or 1 s
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content_tags.quantities[5]the tagger's words
content_tags85% — correct-trial criterion each rat had to reach in a session before moving on in training
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content_tags.quantities[6]the tagger's words

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