Brain activity during intra- and cross-modal priming: new empirical data and review of the literature — TEI-tagged view

Carlesimo, Turriziani, Paulesu, Gorini, Caltagirone, Fazio, Perani · 2004 · neuroscience · doi:10.1016/s0028-3932(03)00148-9 · full text at the source · TEI xml · tagged edition · index · concepts · authors
Where this record's text came from. faceted 2026-08 by reading the locally held text (pdftext); every evidence string verified as an exact substring of that text before merging. method is 'pet-imaging'; the vocabulary listed in the schema offers 'fmri' but no PET value, and calling an H2-15O PET study fMRI would misdescribe it, so I coined the hyphenated value and flag it here for the controlled-vocabulary pass. Claim type is 'existence' (a dissociation between two priming conditions occurs) rather than 'mechanism' - the mechanistic reading, 'more efficient access to output lexical representations and involuntary retrieval of the recent episode', is offered by the authors as a likely interpretation, not as a tested mechanism. Note the second claim_relation: the contradiction is with the authors' OWN earlier behavioural work (Carlesimo et al., 1996) as well as Graf et al., and they explain it away via the baseline anomaly recorded in the third limitation. The paper also reports a sub-threshold BA 19 deactivation close to Badgaiyan's peak, i.e. a partial recovery of the finding it otherwise contradicts; I did not encode that as a 'replicates' relation because the effect was below the conventional threshold and the authors present it as such. Replication status is 'untested' for this paper's own novel left-fusiform finding. 2026-08-19 schema-0.3 pass: every quote verified as an exact substring of the staged text and anchored at merge time; concept terms verified present; every edge endpoint an existing node.
Other fields define these differently the same word, defined another way in another discipline
meta-analysis 4 fields · repetition priming 2 fields
Tags on this paper every tag the record carries, whether or not the words occur in the text below — a number is how many papers in the corpus carry that tag; a tag with no number is unique to this paper
repetition priming20 implicit memory9 within-modality modality5 neuroimaging4
Method, as described: pet-imaging

Our tag layer for this paper

Cross-disciplinary analysis
content-tags & facets: phenomenon · claim-type · cross-domain-transfer · mechanism · claim-relation · replication-status · limitation — grounded in the full text
phenomenonrepetition priming— “Repetition priming is a form of implicit memory that typically manifests as a facilitation in re-processing recently experienced stimuli or as a bias in completing fragments with recently encountered items when test instructions do not make any reference to prior events.”
claim-typeexistence— “A straightforward result of the present study is that auditory-to-auditory within-modality and auditory-to-visual cross-modality stem completion priming are associated with distinct patterns of rCBF changes as detected by PET.”
method — evidence— “A positron emission tomography (PET) study was conducted to investigate the neurofunctional correlate of auditory within-modality and auditory-to-visual cross-modality stem completion priming.”
mechanismThe left inferior temporal/fusiform region mediates interaction between phonological and orthographic word codes, and this shared abstract code is what carries facilitation across modalities— “In particular, it suggests that this cortical region might be involved in the complex interactions between the phonological and orthographic codes of words which ultimately allow for the cross-modality facilitation in verbal stimulus re-processing.”mechanisms[0]
mechanismRight prefrontal increases arise from post-retrieval awareness that the generated word was recently encountered (involuntary conscious memory), not from deliberate episodic search driving the completions— “The substantially low level of the completion rate and the lack of an increase in priming magnitude across successive study-test blocks suggest that the contribution of such mechanisms is more in eliciting post-retrieval awareness of a recent encounter with the generated word than in actual support for active retrieval.”mechanisms[1]
mechanismLeft prefrontal increases reflect more efficient access to output lexical representations of recently encountered words rather than generic word-fluency demand— “Rather, rCBF changes in this region should be considered as the expression of more efficient access to output representations of recently encountered words prompted by either phonological or semantic cues.”mechanisms[2]
contradicts Badgaiyan et al. (1999); Badgaiyan et al. (2001)— “This is in contrast with previous reports in the literature which showed rCBF decreases in the lateral occipital cortex (BA 19) during auditory stem completion priming (Badgaiyan et al., 1999; Badgaiyan et al., 2001).”claim_relations[0]
contradicts Carlesimo, Marfia, Loasses, & Caltagirone (1996); Graf et al. (1985)— “Previous behavioural studies consistently reported significantly larger within-modality than cross-modality stem completion priming (e.g. Carlesimo, Marfia, Loasses, & Caltagirone, 1996; Graf et al., 1985).”claim_relations[1]
contradicts Badgaiyan et al. (1999); Schacter et al. (1999)— “However, the conclusion that cross-modality priming is more exposed to contamination by explicit retrieval strategies than within-modality priming is not supported by neuropsychological evidence.”claim_relations[2]
builds-on Buckner et al. (2000)— “Support for the view that regions in the left inferior temporal cortex can modulate their neural activity in response to verbal stimuli independent of stimulus-driven perceptual processes comes from an fMRI study by Buckner et al. (2000).”claim_relations[3]
senseTHE ASYMMETRY IS STATED AS SETTLED BACKGROUND, AND THREE YEARS LATER IT IS AN ARTEFACT. `In most cases, the magnitude of the priming effect is LARGER when the same modality of stimulus presentation is used for study and testing than when it differs (Graf, Mandler, & Haden, 1982).` Written as review, not as a claim under test - which is what makes it worth tagging. lukatela2007 minimised study-test asymmetries across five experiments and found EQUAL magnitudes, with the conventional advantage returning only in a within-subjects design. Kirsner1986 reasons from the asymmetry; this record goes looking for its brain basis; lukatela2007 dissolves it. Three records, one day, none citing the others— “In most cases, the magnitude of the priming effect is larger when the same modality of stimulus presentation is used for study and testing than when it differs (Graf, Mandler, & Haden, 1982).”senses[0]
senseAND THE NEURAL RESULT IS A DISSOCIATION IN DIRECTION, NOT JUST IN LOCATION: cross-modal priming gave a larger rCBF DECREASE in left inferior temporal and fusiform cortex - regions tied to modality-independent lexical retrieval - while `within-modality auditory priming was associated with a bilateral pattern of prefrontal rCBF increase.` Different regions and opposite signs. Whatever the behavioural asymmetry turns out to be, these two conditions are not one process running at two strengths in this data - which is a constraint that survives even if lukatela2007 is right that the behavioural difference is a design artefact— “Instead, within-modality auditory priming was associated with a bilateral pattern of prefrontal rCBF increase.”senses[1]
senseTHE DEFINITION PUTS THE CRITERION IN THE INSTRUCTIONS, WHICH IS EASY TO READ PAST: repetition priming manifests as facilitation or a completion bias `when test instructions do not make any reference to prior events.` Not `when the subject is unaware`, not `when memory is not consciously used` - when the experimenter did not mention it. The construct is operationalised by what was said to the participant, and the 90%% discussion of this same paper concedes that `involuntary conscious memory` may occur anyway when the study context is reinstated. The definition and the caveat are in the same paper— “Repetition priming is a form of implicit memory that typically manifests as a facilitation in re-processing recently experienced stimuli or as a bias in completing fragments with recently encountered items when test instructions do not make any reference to prior events.”senses[2]
controlthe 30-word stimulus sets were counterbalanced across subjects so each occurred equally often in the within- and cross-modality conditions and in the priming and baseline scans — held — rules out that a condition difference is a difference between the word sets— “The stimuli were counterbalanced across subjects so that each 30-word set occurred equally often in the within and cross-modality condition, priming and baseline scans.”controls[0]
controlcondition and scan order counterbalanced across blocks and subjects in a LATIN SQUARE design — held — rules out that the effect is an order effect across the scanning session— “The order of within and cross-modality conditions as well as priming and baseline scans was also counterbalanced across blocks and subjects (Latin square design).”controls[1]
controla postscan debriefing asked whether subjects had noticed that some stems came from the study list - and NEARLY ALL OF THEM HAD — failed — rules out that the priming is implicit - the control was run to establish that subjects were unaware, and it established the opposite— “Moreover, informal assessment of subjects during postscan debriefing revealed that nearly all subjects in both withinand cross-modality conditions were aware of the fact that some of the stems came from the study list.”controls[2]
noterepetition priming —is-a→ implicit memory — THE CLEANEST 'is-a' I HAVE CUT THIS SESSION, AND THEY ARE RARE. 'Repetition priming is a form of implicit memory' - the relation is the sentence's main verb, both endpoints are named as words, and there is no hedge to preserve. Weight 0.95. Most taxonomy in this literature has to be inferred from how terms are used together; here it is asserted directly, in an introduction, as the thing the reader is expected to already accept.— “Repetition priming is a form of implicit memory that typically manifests as a facilitation in re-processing recently experienced stimuli or as a bias in completing fragments with recently encountered items when test instructions do not make any reference to prior events.”concept_edges[0]
weightrepetition priming —is-a→ implicit memory — 0.95— “Repetition priming is a form of implicit memory that typically manifests as a facilitation in re-processing recently experienced stimuli or as a bias in completing…concept_edges[0]
outcome (stated by the tagger, no quotation)control — heldcontrols[0]
outcome (stated by the tagger, no quotation)control — heldcontrols[1]
outcome (stated by the tagger, no quotation)control — failedcontrols[2]
replicationuntested
limitationThe cross-modality parietal and temporal activations cannot be attributed a specific role because the interaction contrasts were not significant.limitations[0]
limitationThe left prefrontal activation specific to within-modality priming is only suggestive, again because the interaction failed.limitations[1]
limitationThe comparability of the two priming effects may be an artefact of a chance difference in the auditory baseline completion rate.
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
limitations[2]
Content tags
content-observations: finding · quantity · variable · definition · key-term — grounded in the full text
findingAuditory-to-visual cross-modality priming produced a significantly larger blood-flow decrease at the left inferior temporal/fusiform boundary than within-modality auditory priming.
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.findings[0]
findingThe interaction analysis confirmed the deactivation difference was specific to the cross-modality condition in left BA 37/20.
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content_tags.findings[1]
findingWithin-modality auditory priming was accompanied by bilateral prefrontal blood-flow increases.
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.findings[2]
findingRight middle frontal activation was significantly greater for within-modality than for cross-modality priming.
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content_tags.findings[3]
findingWithin- and cross-modality priming effects were of comparable size behaviourally (4.4 and 3.9).
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.findings[4]
findingThe magnitude of the left inferior temporal deactivation tracked each subject's behavioural cross-modality priming, tying the imaging effect to behaviour.
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.findings[5]
findingNo blood-flow decrease related to within-modality priming reached the threshold used.
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.findings[6]
findingPriming size did not change across successive study-test blocks.
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content_tags.findings[7]
quantityEight — number of participants scanned (male college students aged 20-27)
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content_tags.quantities[0]
quantity12 scans — number of PET scans per subject, three in each of the four conditions
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
content_tags.quantities[1]
quantity360 — number of common Italian target words making up the stem-completion materials
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content_tags.quantities[2]
quantity6.51 per million — mean lexical frequency of the target words in Italian
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content_tags.quantities[3]
quantity7.7 versus 3.5 — mean number of stems completed with target words in priming versus baseline scans
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content_tags.quantities[4]
quantity4.4 and 3.9 — size of the within-modality and cross-modality priming effects, which did not differ reliably
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content_tags.quantities[5]
quantityF = 42.2; P < 0.001 — main effect of condition (priming versus baseline) on stem completion
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content_tags.quantities[6]
quantityZ = 2.59 — sub-threshold deactivation peak in right BA 19 for within-modality auditory priming, found only in an exploratory analysis
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content_tags.quantities[7]
quantityZ = 2.0; P = 0.02 — strength of the correlation between left BA 37/20 deactivation and behavioural cross-modality priming
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content_tags.quantities[8]
variablemodality of stem presentation (auditory versus visual) (independent)
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content_tags.variables[0]
variableregional cerebral blood flow (rCBF) (dependent)
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content_tags.variables[2]
variablepercentage of target words (dependent)
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content_tags.variables[3]
variablefoil lists (control)
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content_tags.variables[4]
definitionrepetition priming
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content_tags.definitions[0]
definitioncross-modality priming
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content_tags.definitions[1]
definitionstem completion paradigm
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content_tags.definitions[2]
definitionwithin-modality priming effect
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content_tags.definitions[3]
definitionbasal temporal language area
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content_tags.definitions[4]
definitioninvoluntary conscious memory
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content_tags.definitions[5]
Concepts
terms this paper carries, each with the sentence it was cut from — the layer that joins one paper to another. Terms with no quote yet are on CONCEPTS.html.
conceptrepetition priming — not defined in this paper's own words; DEFINED HERE IN ONE SENTENCE AND THE DEFINITION IS DOING REAL WORK: 'a facilitation in re-processing recently experienced stimuli or as a bias in completing fragments with recently encountered items when test instructions do not make any reference to prior events.' That final clause is the whole operational content - it is what separates this from recall, and it is a fact about the INSTRUCTIONS, not about the subject
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concepts[0]
conceptimplicit memory — not defined in this paper's own words; the category repetition priming belongs to. Its evidence in this literature is dissociation from episodic memory in amnesia - patients with mesio-temporal or diencephalic damage show normal priming and severely impaired episodic performance - which is a claim about populations, not about a mechanism
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
concepts[1]
conceptwithin-modality — not defined in this paper's own words; study and test in the same modality. The condition with a bilateral PREFRONTAL rCBF INCREASE - increase, where the priming literature's standard neural signature is a decrease. That inversion is the finding
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concepts[2]
conceptmodality — not defined in this paper's own words; whether study and test used the same sense. Stated here as established that priming is 'larger when the same modality ... is used for study and testing than when it differs' - and lukatela2007, three years later, shows the difference disappears once study-test asymmetries are equalised. This record inherits the asymmetry as background
Quotation withheld — this paper is not ours to reproduce, and the page has already quoted as much of it as the rights layer allows. The tag, its field and its confidence stand; the sentence is at the publisher.
concepts[3]
Statistics — cross-field join keys
field-invariant statistical terms, used in their statistical sense (gated on a number / symbol / test). A p-value or a standard deviation means the SAME thing in physics, biology, psychology and sociology — so these are the strongest cross-field join keys. Grounded verbatim.
ANOVA F as written: three-way ANOVA
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content_tags.statistics[0]
F-test F as written: F = 16.8; P < 0.01 with d.f. = 1, 7
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content_tags.statistics[1]
t-test t as written: the t statistic
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content_tags.statistics[2]
z-score Z as written: Z score maps (SPM{Z})
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content_tags.statistics[3]
general linear model as written: the general linear model
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content_tags.statistics[4]
random effects analysis as written: random effect analysis
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content_tags.statistics[5]
p-value P as written: statistical threshold one-tailed, P < 0.001 uncorrected
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content_tags.statistics[6]
correlation as written: significant negative correlation
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content_tags.statistics[7]
meta-analysis as written: a meta-analysis of the activation and de-activation patterns
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content_tags.statistics[8]

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